March 5, 2021
Member/Center Highlights
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Cancer Disparities Virtual Symposium continues today, Thursday recordings available
Today is day two of the 5th Annual Cancer Disparities Symposium, Navigating Cancer Disparities: Lessons Learned and How to Move Forward, presented by the Case Comprehensive Cancer Center's Office of Community Outreach and Engagement.

Yesterday's event kick-off had fantastic presentations, intriguing panel discussions, and thought-provoking questions from the audience. Recordings of yesterday's sessions on COVID-19 and cancer disparities and improving the participation of minority and underserved populations in cancer clinical trials are now available in the Whova app for all registered attendees, along with access to the poster session.
Today's session topics include the interplay of biology and social determinants of cancer disparities and the many pains of cancer: physical, emotional and financial, beginning at 8:15 am ET. Day two attendees also have the opportunity to participate in an in-depth discussion of the book Just Medicine: A Cure for Racial Inequality in American Health Care by Dayna Bowen Matthew.
Otis Brawley
Today's Distinguished Scientific Keynote

Otis W. Brawley, MD, an internationally-recognized expert in cancer prevention and control, will present the symposium's Scientific Keynote today at noon ET. After 20+ years as Chief Medical Officer at the American Cancer Society, he leads a broad interdisciplinary research effort on cancer health disparities at the Johns Hopkins Bloomberg School of Public Health and Kimmel Cancer Center.
About the Symposium
This multi-disciplinary event is open to all researchers, clinicians, health professionals, community outreach groups, community-based organizations, patient advocates and trainees. Though the symposium is happening virtually, attendees will experience the conference using Whova, our official web-based conference app, to view presentations and ask questions in real-time, as well as network with others behind the scenes. We invite you to view the updated symposium agenda and secure your access to today's presentations and yesterday's session recordings!
Case CCC researchers to lead Northeast Ohio initiative to increase prostate cancer screening in African American men
African American men in Cuyahoga County have a 60% increased risk of being diagnosed with prostate cancer and an 80% increased risk of dying from prostate cancer compared to white men, according to data from the Case Comprehensive Cancer Center.

With a new $2.75 million, three-year grant from the Bristol Myers Squibb Foundation, researchers at the Case Comprehensive Cancer Center at Case Western Reserve University will collaborate with a team of community partners in a different approach to fight this health disparity.

The Cleveland African American Prostate Cancer Project, directed by Erika Trapl, PhD, director of the Office of Community Outreach and Engagement at the Case Comprehensive Cancer Center, will develop and implement a comprehensive, sustainable, community-based program to increase the number of African Americans screened for prostate cancer.
Cleveland Clinic celebrates 100 years of care
On February 26, 1921, four physicians hosted a ceremony in Cleveland, Ohio to celebrate the opening of their group practice, unveiling a new model of care based on cooperation between clinicians. Throughout the year, Cleveland Clinic is celebrating its 100-year history with virtual events, digital experiences and community initiatives to honor their past and celebrate what is to come.

The centennial celebration kicked off this past Friday, February 26, with a virtual Founders Day presentation featuring remarks from Cleveland Clinic CEO and President Tom Mihaljevic, MD, special musical performances, the world premiere of a branded docuseries, "A Century of Care" and a discussion of healthcare in the next 100 years by Cleveland Clinic leaders from around the world.
Trailer for "A Century of Care" Docuseries
MetroHealth forms its Center for Cancer Research, dedicated to delivering cutting-edge care to everyone
From MetroHealth: Bingcheng Wang, PhD (pictured), Director of the Division of Cancer Biology in the Department of Medicine and Director of Basic Sciences in the MetroHealth Research Institute, has assembled an impressive team of cancer researchers who are bringing cutting-edge care to The MetroHealth System and its hundreds of thousands of patients.

William Tse, MD, is training blood cells to become cancer-killing CAR T cells so patients can beat cancer without the toxic side effects of chemotherapy and radiation. Khalid Sossey-Alaoui, PhD, is working to understand why triple-negative breast cancer occurs much more often in African-American women so he can help end the dreaded disease. Zhisan Wang, MD, PhD, is searching for the biological signal in patients’ bodies that tell doctors lung cancer is there – long before it becomes deadly.

They are four of eight nationally and internationally recognized researchers forming a new cancer research team in Cleveland focused on more than curing one of the most feared diseases. The team, which is backed by millions of dollars in support and grants and dozens of research assistants, will also focus on ending the racial, ethnic, social and economic inequities that impact cancer diagnosis and treatment.
University Hospitals Seidman Cancer Center Earns National Pancreas Foundation Center Designation
University Hospitals Seidman Cancer Center, part of the NCI-designated Case Comprehensive Cancer Center, has been nationally recognized as an approved NPF Center by the National Pancreas Foundation. NPF Centers are awarded after a rigorous audit review to determine that an institution’s focus is on multidisciplinary treatment of pancreatic cancer, treating the “whole patient” with a focus on the best possible outcomes and an improved quality of life.

“We are honored that UH Seidman Cancer Center has been designated as NPF Center for treatment of pancreatic cancer,” said Theodoros N. Teknos, MD President and Scientific Director of Seidman Cancer Center and Deputy Director of Case Comprehensive Cancer Center. “Having the NPF Center designation will help distinguish University Hospitals as an institution whose focus is on providing the best and most innovative care possible.”

The news follows last month's announcement that the UH Seidman Cancer Center is also expanding to Lorain County, constructing a new cancer center in Avon, OH. “Our intent was to create a brand new, state-of-the-art facility, which will provide the residents of Lorain County and surrounding communities leading-edge cancer care close to home,” said Dr. Teknos.
Federal grant writing workshop to be held weekly this summer, submit applications for participation by March 15
The Case Comprehensive Cancer Center invites applications to participate in a summer-long, weekly federal grant writing workshop. The longitudinal workshop will occur Wednesday afternoons from 3:00 to 4:30 pm, beginning April 28, 2021 and ending August 4, 2021 (note: the first two sessions on April 28 and May 5 will be 3:00-5:00 pm).

The program will be capped at 10 individuals, necessitating a competitive application process. The review committee will prioritize Early Career Faculty but will consider applications from more Senior Faculty. The program will focus on writing a successful grant application for cancer-related NIH R01 grants. Those accepted to the program will be notified in early April 2021. The deadline for submissions is Monday, March 15, 2021.
What's Coming Up
Mark Your Calendar
Cancer Center Seminar Series
TODAY, March 5, 2021, 12p via Live Stream
Today's Cancer Center Seminar will stream live from the 5th Annual Cancer Disparities Symposium and features internationally-recognized expert in cancer prevention and control, Otis W. Brawley, MD.

Brawley’s research focuses on developing cancer screening strategies and ensuring their effectiveness. He has championed efforts to decrease smoking and implement other lifestyle risk reduction programs, as well as to provide critical support to cancer patients and concentrate cancer control efforts in areas where they could be most effective. Brawley currently leads a broad interdisciplinary research effort on cancer health disparities at the Bloomberg School of Public Health and the Johns Hopkins Kimmel Cancer Center, striving to close racial, economic, and social disparities in the prevention, detection, and treatment of cancer in the United States and worldwide. He also directs community outreach programs for underserved populations throughout Maryland.
Cancer Center Seminar Series
Friday, March 12, 2021, 12p via Zoom
Next week's Cancer Center Seminar features Thomas Gajewski, MD, PhD, presenting on behalf of the Hematopoietic and Immune Cancer Biology Program.

Dr. Gajewski is the AbbVie Foundation Professor of Pathology and a professor of the Ben May Department of Cancer Research at the University of Chicago.

He investigates and develops new treatments for patients with melanoma and has a special interest in the development of immunotherapies against this disease. Dr. Gajewski also leads development of immune-based therapies for other cancers, using new laboratory data on how the immune system is regulated to develop novel clinical trials.

Dr. Gajewski serves as an editor for Cancer Research and Journal for Immunotherapy of Cancer. In addition, he is immediate past president of the Society for Immunotherapy of Cancer and has served on the program committees for the American Society for Clinical Oncology (ASCO) and the American Association for Cancer Research (AACR).
Additional Upcoming Events
Management of Checkpoint Inhibitor-Related Toxicity Virtual Updates
March 5, 2021
The goal of the program is to bring together a multidisciplinary group of clinicians to share expertise and improve the care of patients receiving immune checkpoint inhibitor therapies.

Specialists in dermatology, endocrinology, gastroenterology, oncology, internal medicine, rheumatology/ immunology, nurses, nurse practitioners, physician assistants and residents/ fellows are invited to attend.
4th Annual International PTEN Symposium
Monday, March 15, 2021
The Genomic Medicine Institute and Center for Personalized Genetic Healthcare at Cleveland Clinic invite you to join the virtual 4th Annual International PTEN Symposium: From Patient-Centered Research to Clinical Care. They are planning an engaging day with an emphasis on advances in the diagnosis, management and treatment of patients with PTEN Hamartoma Tumor Syndrome (PHTS).

Pier Paolo Pandolfi, MD, PhD, FRCP, senior scientist at the Renown Institute for Cancer and honorary professor of molecular biology at the University of Turin, will deliver the morning keynote address. Neil Friedman, MBChB, pediatric neurologist and director of quality, outcomes, and innovation at Barrow Neurological Institute at Phoenix Children’s Hospital, will deliver the afternoon keynote address on the neurological spectrum of PHTS. Other topics include hormone use and high-risk patients, gynecological cancer risks, updates on PTEN clinical trials, and autism. Please refer to the symposium agenda for more details about this year’s speakers and topics.
NCCN Virtual Annual Conference
March 18-20, 2021
In response to the ongoing COVID-19 pandemic, the National Comprehensive Cancer Network (NCCN) has transitioned the NCCN 2021 Annual Conference to a to a live virtual format.

Designed to meet the needs and improve the competence and performance of the interprofessional oncology care team, including physicians, nurse practitioners, nurses, physician assistants, pharmacists, and other relevant health care professionals who manage the care of patients with cancer, this three-day virtual event will offer more than 35 educational sessions covering a range of topics such as:

  • Updates to NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) 
  • New and emerging therapies, controversies in treatment, and best practices in the delivery of oncology care  
  • Issues surrounding HPV vaccination  
  • Racial disparities in guideline-adherent cancer care  
  • Effects of the pandemic on cancer care  
  • Best practices for incorporating patient-reported outcomes into oncology care

Throughout this three-day virtual event, educational sessions will include a mix of challenging case reviews, interactive polling, and moderated Q&A providing participants the opportunity to reinforce knowledge and develop strategies for the management of a variety of cancers.
AACR Annual Meeting 2021
April 10-15 and May 17-21, 2021 | Virtual
The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.
Cell-Based Therapies and Tissue Engineering Short Course
May 19-20, 2021

The Skeletal Research Center and the Department of Biology of Case Western Reserve University are pleased to present the twentieth annual short course entitled: “Cell-Based Therapies and Tissue Engineering”, running from May 19 through May 20, 2021.

Registration is now open. The 2021 program is here. To download a flyer, please click here.

Who Should Attend:
This course is intended for graduate students, post-graduate students and health science professionals who are interested in tissue engineering and regenerative medicine approaches with emphasis on translational research principles and protocols used or being modeled for direct clinical use.
AACI Clinical Research Innovation 13th Annual Meeting
July 13-15, 2021
Save the date! The 13th Annual AACI Clinical Research Innovation (CRI) Meeting will be held July 13-15, 2021. Information about the meeting format, abstract submissions, and registration will be made available in early 2021.
VeloSano logo
VeloSano 8 Bike to Cure Weekend
Date Change: September 10-12, 2021

We are looking ahead with optimism to VeloSano 8 (2021), with a goal of providing opportunities to reunite our VeloSano community in a variety of safe and meaningful ways!

VeloSano's hope is to offer options for anyone to participate in any way they are most comfortable - whether riding with us during "Bike to Cure" weekend September 10-12; riding virtually, or by choosing your own activity to participate anytime, anywhere as a Virtual Fundraiser.
Funding Opportunities
Available award: Up to $40,000
LOI Deadline: March 26, 2021
Full Application Deadline: April 23, 2021
Available award: $75,000 for one year
LOI Deadline: April 2, 2021
Full Invited Application Deadline: April 16, 2021
Available award: Up to $120,000 for one year
Deadline: April 16, 2021
Available award: $75,000 for 18 months
Deadline: April 16, 2021
Available award: $180,000 for 18 months
Deadline: April 16, 2021
Available award: $25,000 for one year
Applications accepted and awarded on a rolling basis

Internal LOI deadline: March 17, 2021
The BCA Exceptional Project Grants provide $100,000 of support for one year. Two Case CCC applicants will be selected for submission. If selected, the full application deadline is July 23, 2021.

Internal LOI deadline: April 14, 2021
The BCA Young Investigator Grants provide $125,000 of support for two years. Two Case CCC applicants will be selected for submission. If selected, the full application deadline is July 23, 2021.
Internal LOI Deadline: March 17, 2021

One Case CCC applicant will be selected to apply for either the V Scholar Program or the Translational Research Program.

The V Scholar Program provides $200,000 of support for two years and the Translational Research Program provides $600,000 of support for three years.
Pew Charitable Trusts
Internal LOI Deadline: April 14, 2021

The Pew-Stewart Scholars for Cancer Research Program provides $75,000 of support per year for four years. One Case CCC applicant will be selected for submission. If selected, the full application deadline is September 9, 2021.
In The News
Cure Today - March 2, 2021
"I think physicians, oncologists in particular, have a lot of concerns about potential drug-drug interactions — and, of course, that also relates to herbs and supplements,” said lead study author Richard T. Lee, MD, director of the Supportive and Integrative Oncology Program at University Hospitals Seidman Cancer Center. Dr. Lee is a member of the Case CCC.
Boston Globe - February 25, 2021
Mark Cameron, PhD, associate professor at the School of Medicine and a member of the Case CCC, noted that some cruise companies are mandating that guests be vaccinated—and discussed whether airlines could be next.
From The NIH
NCI supports NIH Effort to End Structural Racism in Biomedical Research
On March 1, Francis S. Collins, MD, PhD director of the National Institutes of Health, launched a new initiative designed to end structural racism in biomedical research called UNITE. In his statement, Dr. Collins committed NIH to instituting new ways to support diversity, equity, and inclusion, and identifying and dismantling any policies and practices that may harm our workforce and our science.

As part of this initiative NIH has issued a Request for Information seeking input on practical and effective approaches to improve and strengthen racial equity, diversity, and inclusion across all facets of the biomedical research enterprise, both within NIH and the external community, and expand research to eliminate or lessen health disparities and inequities.

On behalf of NIH, we invite you to share your perspective and recommendations as we thoughtfully consider our proactive approach to address racial and health inequities in biomedical research. Comments can be submitted through the submission website and must be received by April 9, 2021.

Please read NCI’s statement, in support of ending structural racism in biomedical research in its entirety.

As we continue to support NIH with the UNITE initiative and further develop our own initiatives to help combat this systemic issue at NCI, we will continue to update you and invite the communities’ input and recommendations.
Weekly NIH Funding Opportunities and Notices
COVID-19 Funding Opportunities and Notices
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