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May 6, 2018
Sharifi Elected to AAP
Nima Sharifi Nima Sharifi, MD, was elected to the prestigious Association of American Physicians (AAP), an honorary society for leading physician-scientists. He was honored at the annual AAP meeting in Chicago. New members are nominated by AAP-member peers and undergo a competitive selection process. In November, Dr. Sharifi was appointed a fellow of the American Association for the Advancement of Science. He is a staff member in the Lerner Research Institute Department of Cancer Biology and holds joint appointments in the Glickman Urological and Kidney Institute and Taussig Cancer Institute.
We've Moved! Case CCC Open House
May 8, 4:45-6p | WRB 1422
The Case Comprehensive Cancer Center Office of the Director and Administration has moved! We are now located on the first floor of the Wolstein Research Building in a newly renovated space. We invite you to come view the new suite, say hello to staff, and enjoy a small reception of food and drinks this Tuesday, May 8 at 4:45p. No RSVP necessary. 
VeloSano 5: Get Involved! 
VeloSano logo Spring is here, and it's time to start building momentum for VeloSano 5! Remember, a ll of the funds raised through VeloSano support cancer research right here in Cleveland. 

Getting involved is easy. Your help and support is appreciated:
  • Join Team Case CCC as a rider from the 12 to 200-mile level. Case CCC Director, Dr. Stan Gerson, will be on the 100-mile route, and looks  forward to riding with you!
  • Raise funds as a virtual rider  on Team Case CCC by signing up and supporting all of us!
  • Join as a volunteer to help before and during the ride to keep us on track, hydrated and cheered on!
  • Come to team events and show your support: Happy Hours scheduled for the following times: 
    Thur, May 10, 4-6p, Washington Place
    Thurs, May 24, 4-6p, TOLI
    Thurs, June 7, 4-6p, Washington Place 
    Fri, June 29, 5-8p, TOLI
Special Cancer Center Seminar Series 
May 11, 12-1p | BRB 105
Kroeger Join us Friday, May 11 at noon in the Biomedical Research Building Frohring Auditorium (BRB 105) for a special  Cancer Center Seminar Series , to hear Nicolaus Kröger, MD, Professor of Medicine and Medical Director of the Department of Stem Cell Transplantation at the University Medical Center Hamburg-Eppendorf , discuss " Role of Allogeneic Stem Cell Transplantation in Multiple Myeloma in 2018 ."

Dr. Kröger's research interest is on stem cell biology and stem cell transplantation, the detection and treatment of minimal residual disease by adoptive immunotherapy or novel drugs, the impact of NK-cell allo-reactivity, optimizing outcome with HLA-mismatched donor, and prevention and treatment of chronic graft-versus-host disease.

From 2006 to 2012, Dr. Kröger served as chairman of the MDS subcommittee of the European Group for Blood and Marrow Transplantation (EBMT), and since 2012 he has been chairman of the Chronic Malignancies Working Party and board member of EBMT, and since 2014 also the chairman of the Scientific Council of EBMT. In 2018 he was elected as President of EBMT (2018-2022).

Dr. Kröger is also chairman of the German Stem Cell Working Group (DAG-KBT) and member of several editorial boards such as Blood, Haematologica and Bone Marrow Transplantation. He is also a member of the Scientific Program Committee and the Editorial Board of the European Hematology Association (EHA) and member of the Scientific Committee of the European School for Hematology (ESH). Additional memberships include societies such as the American Society of
Hematology (ASH), European Hematology Association (EHA), European Society of Medical Oncology (ESMO), the American Society of Clinical Oncology (ASCO) , the International Working Group for Myelofibrosis Research and Treatment (IWG-MRT) and the International Myeloma Working Group (IMWG).

CSC 2018 - web banner
The Case Comprehensive Cancer Center (Case CCC) and National Center for Regenerative Medicine (NCRM) invite you to Cancer Stem Cell Conference (CSC 2018)! Now in it's third year, CSC 2018 will feature renowned thought leaders in the field of cancer stem cell research. This conference is guaranteed to offer cutting-edge keynote presentations from a variety of niches within the field. Join world-class investigators for this 3-day summit and network with scientists and clinicians advancing cancer stem cell research and therapeutic applications.

Conference Highlights
  • The agenda will integrate invited talks from thought leaders in the CSC field with short talks from early-stage investigators and trainees selected from submitted abstracts.
  • Pre-conference career development workshop for junior faculty and trainees
    • Meet the Editors: Natalie Cain, PhD (CellReports), Mark Landis, PhD (CancerDiscovery) and Teodoro Pulvirenti, PhD(JEM)
    • Discussion of NIH grants: Michael Espey, PhD (NCI) and Michelle McGuirl, PhD (NIH)
  • Young Investigator Awards available to support travel for senior trainees or junior faculty (less than 5 years from their first independent position). Submit your abstracts by May 15 to be eligible. 
  • Opportunity to share ideas with world-class investigators in stem cell research. 2016 CSC was attended by over 300 from 20 countries and 25 U.S. states. This year's conference is on track to attract a similar crowd of colleagues.
Keynote Speakers
  • Norman E. 'Ned' Sharpless, MD (NCI)
  • John S. Condeelis, PhD (Einstein)
  • Irving Weissman, MD (Stanford)
  • Zena Werb, PhD (UCSF)
Call for Abstracts Deadline: May 15

Discounts for early registration through May 31

Gerson Participates in Biden Cancer Initiative Colloquium
AACI Update - May 2018
AACI President Stanton L. Gerson, MD, director of the Case Comprehensive Cancer Center, in Cleveland, was a panelist at the Biden Cancer Initiative Colloquium, held April 17 at the American Association for Cancer Research Annual Meeting 2018, in Chicago. Dr. Gerson detailed a collaboration between Case and the GW Cancer Center, in Washington, DC, to launch a smoking cessation program. "Public interest in cancer discovery has incredible traction, and many across the country are helping to both expand the impact of our discoveries and to instill a sense of urgency that we include every household in the benefits of cancer research," Dr. Gerson said after the event. 
6th Annual Harrington Prize for Innovation in Medicine
Deadline: Aug 28, 2018
National and international nominations are being sought for the 
2019 Harrington Prize for Innovation in Medicine , which honors a physician-scientist who has moved science forward with achievements notable for innovation, creativity and the potential for clinical application. 

The Harrington Prize, which carries a $20,000 honorarium, is a collaboration between The American Society for Clinical Investigation (ASCI), one of the nation's oldest and most respected medical honor societies, and the Harrington Discovery Institute at University Hospitals in Cleveland, Ohio-part of The Harrington Project for Discovery & Development. The Harrington Discovery Institute is a nonprofit institute dedicated to supporting physician-scientists, and all scientists in areas of unmet therapeutic need, in their work to transform discoveries into medicines for the benefit of society.
Department of Defense FY18 Lung Cancer Research Program (LCRP)
CDMRP logo
Concept Award supports the exploration of a highly innovative new concept or untested theory that addresses an important problem relevant to lung cancer. All investigators at or above the level of postdoctoral fellow (or equivalent) are eligible. An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by, or affiliated with, an eligible organization.
LOI Deadline: Jul 26, 2018
Application: Aug 9, 2018

Career Development Award: supports early-career, independent investigators to conduct impactful research under the mentorship of an experienced lung cancer researcher as an opportunity to obtain the funding, mentoring, and experience necessary for productive, independent careers at the forefront of lung cancer research. This award is intended to support impactful research projects with an emphasis on discovery. 
LOI Deadline: Sep 6, 2018
Application: Sep 26, 2018

Idea Development Award: promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress toward eradicating deaths and suffering from lung cancer. 
LOI Deadline: Jun 26, 2018
Application: Sep 26, 2018

Investigator Initiated Translational Research Award: Investigator-Initiated Translational Research Award mechanism supports translational research that will develop promising ideas in lung cancer into clinical applications. Translational research may be defined as an integration of basic science and clinical observations. Observations that drive a research idea may originate from a laboratory discovery, population-based studies, or a clinician's firsthand knowledge of patient care. The ultimate goal of translational research is to move a concept or observation forward into clinical application. However, Principal Investigators (PIs) should not view translational research as a one-way continuum from bench to bedside. The research plan must involve a reciprocal flow of ideas and information between basic and clinical science. 
LOI Deadline: Sep 6, 2018
Application: Sep 26, 2018

Translational Research Partnership Award:  supports partnerships between clinicians and research scientists that will accelerate the movement of promising ideas in lung cancer into clinical applications. This award supports the development of translational research collaborations between two independent, faculty level (or equivalent) investigators to address a central problem or question in lung cancer in a manner that would be less readily achievable through separate efforts. One partner in the collaboration must be a research scientist and the other must be a clinician. In addition, one partner in the collaboration is strongly encouraged to be an active duty Service member or Federal employee from a Department of Defense (DoD) military treatment facility or laboratory, or a Department of Veterans Affairs (VA) medical center or research laboratory. 
LOI Deadline: Sep 6, 2018
Application: Sep 26, 2018
NIH BULLETIN- Notices and Funding Opportunities
NCI Participation in PA-18-141, Mechanisms, Models, Measurement, & Management in Pain Research (R01 Clinical Trial Optional)(NOT-CA-18-068)

Program Announcements
Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (Collaborative U54 Clinical Trial Optional)(PAR-18-767)
Deadline: Jan 9, 2019; Jan 9, 2020

Novel Nucleic Acid Sequencing Technology Development (R01 Clinical Trial Not Allowed)(RFA-HG-18-001)
 Deadline: Jun 27, 2018; Jun 27, 2019; Jun 26, 2020

Novel Nucleic Acid Sequencing Technology Development (R21 Clinical Trial Not Allowed)(RFA-HG-18-002)
Deadline: Jun 27, 2018; Jun 27, 2019; Jun 26, 2020

Novel Nucleic Acid Sequencing Technology Development (R43/R44 Clinical Trial Not Allowed)(RFA-HG-18-003)
Deadline: Jun 27, 2018; Jun 27, 2019; Jun 26, 2020

Harnessing Big Data to Halt HIV (R01 Clinical Trial Optional)(PAR-18-764)
Deadline: Standard dates apply

Mon, May 7
Genomic Medicine Institute 
Angela Ting, PhD
Associate Professor, Genomic Medicine Institute, Cleveland Clinic
"The role of DNA methylation in modulating transcriptome diversity"
12p NE1-205 Cleveland Clinic

Pathology Research Seminar Series
Alex Gooding 
Schiemann Lab, Oncology, CWRU
"Elucidating the role of the lncRNA BORG during beast cancer metastasis"
12p WRB 1-413

Cancer Center Research Chalk Talk
Vinay Varadan, PhD
Assistant Professor, Oncology, CWRU
1p WRB 3-136

Tumor Immunology and Immunotherapy Meeting
4p CA5-124 Cleveland Clinic
Tues, May 8
Cancer Center Research in Progress Seminar
3p WRB 3-136

2018 Adamczyk Lecture
Maryellen Giger, PhD 
A.N. Pritzker Professor of Radiology, University of Chicago; President, SPIE, The International Society for Optics and Photonics; Inaugural Editor-in-Chief, Journal of Medical Imaging; Co-founder and Scientific Advisor, Quantitative Insights "Radiomics and machine learning in breast cancer image analysis"
4p Tinkham Ballroom C
Reception to follow

Case CCC Office Suite Open House/Reception
WRB 1422
Wed, May 9
PRCHN Seminar
Anna Thornton, MPH
REACH Project Manager; Shari Bolen, MD, and Jonathan Lever, MPH, Better Health Partnership; and Samantha Smith, MA, Cuyahoga County Board of Health 
"Chronic disease self-management program: Innovations and partnerships to make a difference in self-reported outcomes"
12p PRCHN conference room
Thurs, May 10
Developmental Therapeutics Journal Club
9a R4-013 Cleveland Clinic

Molecular Biology and Microbiology Seminar
1p SOM W203

Team Case CCC Velosano Happy Hour 
4-6p Washington Place Inn and Bistro
Fri, May 11
Taussig Cancer Institute Grand Rounds
Daniel Stover, MD
Ohio State University
"Cell-free DNA in breast cancer: Hype, hope, and reality"
8a CA5-120 Cleveland Clinic

Special Cancer Center Seminar Series
Nicolaus Kröger, MD
Professor, Medicine; Medical Director, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf 
"Role of allogeneic stem cell transplantation in multiple myeloma in 2018"
12p BRB 105
Mon, May 14
Genomic Medicine Institute
Hippokratis Kiaris, PhD Associate Professor, Director of the Peromyscus Genetic Stock Center, University of South Carolina
"Stressing the deer mice: Modeling the unfolding protein response in genetically diverse animals"
12p NE1-205 Cleveland Clinic
Thurs, May 17
Developmental Therapeutics Journal Club
9a R4-013 Cleveland Clinic

Molecular Biology and Microbiology Seminar
1p SOM W203

Cowden Craft Series: Flight Night - Event to benefit the Meredith A. Cowden Foundation
6-10p Masthead Brewing
Fri, May 18
Taussig Cancer Institute Grand Rounds
David Palma, MD
London Health Sciences Center 
"The Oligometastatic State: Real Entity, or Fake News?"
8a CA5-120 Cleveland Clinic

Case Gastrointestinal Cancers SPORE Retreat
8:15a Tinkham Veale University Center 
Tues, May 22
Pharmacology Spring Seminar
Karen Knudsen, PhD
Director, Sidney Kimmel Cancer Center;  Hilary Koprowski Endowed Professor and Chair, Department of Cancer Biology;  Professor, Cancer Biology, Urology, Radiation Oncology, and Medical Oncology; Thomas Jefferson University
"Targeting DNA repair dysfunction in prostate cancer"
12p Wood Bldg, SOM331


Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center 
2103 Cornell Road, Ste 1422
Cleveland, OH 44106-7285