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November 21, 2018
MEMBER/CENTER HIGHLIGHTS
Lathia and Tiwari Named in Crain's Cleveland's Forty Under 40
The Case Comprehensive Cancer Center (Case CCC) congratulates Justin D. Lathia, PhD and Pallavi Tiwari, PhD for being named in Crain's Cleveland Business' 2018 issue of "Forty Under 40."
Researcher in the department of cellular and molecular medicine of the Lerner Research Institute at Cleveland Clinic, Lathia is also associate professor of molecular medicine in the school of medicine at Case Western Reserve University (CWRU).  Tiwari   is  assistant professor 
of biomedical engineering at  
CWRU Both are  members  of the Case  CCC's  Molecular Oncology Program . Chosen under-40s are recognized for their contributions to Northeast Ohio and dedication to its future. more>
Khalil Awarded $1.85M from NIH, Seeks to Learn How Noncoding Genes Work in Progression of Colorectal Cancer
The National Institutes of Health have granted Ahmad Ahmed Khalil Khalil, PhD $1.85 million to build on a recent discovery that non-coding genes contribute to cancer's development and spread. Khalil is professor of genetics and genome sciences at Case Western Reserve University School of Medicine and member of the Case CCC's Molecular Oncology Program.
"M y colleagues and I have shown that some lincRNAs seem to also help colon cancer cells avoid cell death, and grow at a much faster rate than their normal counterparts. This finding opens up a parallel cancer-fighting track that can significantly increase the chances of overcoming this invidious disease," said Khalil. The emerging findings could result in leveraging technologys to target RNA molecules rather than proteins, what Khalil calls a "new dimension in the fight against cancer." more>
Mining Properties of Gold to Treat Cancer
Professor of physics and medicine at Case Western Reserve University,  Giuseppe Strangi, PhD
Strange-Giuseppe PhD
and his team are working on ch emical ways to "zipcode" gold nanoparticles to specific cancer cells. Strangi is a member of the GU Malignancies Program Case Comprehensive Cancer Center . The research involves the interaction of the free electrons at gold's surface with light that could be manipulated to kill cancer cells. "We have different strategies here, not using drugs, but using the physical properties of nanoparticles," he said. more>
MARK YOUR CALENDARS
American Society of Hematology 60th Annual Meeting & Exposition
December 1-4, 2018 | San Diego, CA

ASH logo The American Society of Hematology will host its 60th Annual Meeting & Exposition the first weekend of December, 2018.

View chairs, presenters and papers from Cleveland-based institutions here.
Cancer Center Seminar Series: "Discovery and characterization of cell active inhibitors of Lactate Dehydrogenase (LDH) using structure-based design"
Nov 30, 12p | WRB Auditorium

Alex Waterson PhD Join us Friday, November 30 at 12p in the WRB Auditorium to hear Alex G. Waterson, PhD  present "Discovery and characterization of cell active inhibitors of Lactate Dehydrogenase (LDH) using structure-based design. Dr. Waterson is director and scientific coordinator at the Vanderbilt Center for Cancer Drug Discovery and research associate professor of pharmacology and chemistry at Vanderbilt University.

A synthetic organic chemist by training, Dr. Alex Waterson joined GlaxoSmithKline as a medicinal  chemist in 2001, contributing to covalently modifying ErbB inhibitors and the B-Raf drug  Dabrafenib. On moving to Vanderbilt in 2008, he helped establish a Vanderbilt center in the  National Cancer Institute (NCI) Chemical Biology Consortium (CBC) and joined Professor Fesik's  fragment-based group. There, he has led primarily oncology drug discovery projects aimed at  direct and indirect inhibition of K-Ras, as well as protease, epigenetic, and cancer metabolism  targets.   more>
3rd Annual Cancer Disparities Symposium
Mar 1, 2019 | Tinkham Veale University Center
Disparities Banner 2019-final
The 3rd Annual Cancer Disparities Symposium will be held Friday, Mar 1, 2019. 

Registration

Registration is now OPEN for this symposium.  
Click here for registration information.

2019 Symposium Highlights
  • Eliseo J. Pérez-Stable, MD, Director, National Institute on Minority Health and Health Disparities (NIMHD), National Institutes of Health (NIH), will discuss cancer disparities research trends and funding opportunities. 
  • Rick Kittles, PhD, Associate Director of Health Equities at City of Hope, will give a research-focused presentation on cancer disparities research. 
  • An entire afternoon session is devoted to research aligned with abstract submissions; this includes oral presentations from selected abstracts, plus a poster session. Students who submit an abstract can attend this symposium free of charge. 
  • The audience for this symposium is diverse in background and field, allowing attendees to interact, network, and expand their knowledge and opportunities for collaboration.
Call for Abstracts

The Case Comprehensive Cancer Center invites multidisciplinary researchers, community agencies and organizations to submit abstracts for presentation at the 3rd Annual Cancer Disparities Symposium. Abstracts will be divided into two tracks: Scientific Research and Community Programs. Meritorious abstracts will be selected for oral presentations. 

**Students who submit an abstract are able to register for FREE! Submit your abstract to  caseccc-ocdr@case.edu   BEFORE  registering. You will be emailed a discount code to be entered on the registration form so that you receive the discount. 

Deadline

Abstracts must be submitted via email ( caseccc-ocdr@case.edu ) by 5pm EST on December 21, 2018.
FUNDING OPPORTUNITIES
Request for Proposals: Endowed Young Investigator Award (YIA) in Mantle Cell Lymphoma (MCL)
Deadline: Dec 13, 2018

The Conquer Cancer Foundation
of ASCO has released a request for proposals for their 2019 Endowed Young Investigator Award (YIA) in Mantle Cell Lymphoma (MCL) provides funding to promising investigators to encourage and promote quality clinical research in MCL. The purpose of this award is to fund physicians during the transition from a fellowship program to a faculty appointment. The Conquer Cancer Foundation welcomes application submissions only from investigators who are committed to conducting clinical and translational MCL research.

The Young Investigator Award is a one-year grant totaling $50,000. This endowed grant allows Conquer Cancer to award a YIA in MCL each year.
Request for Applications: Barrett's Esophagus Translational Research Network (BETRNet) Pilot Project Award Program
Deadline: Jan 31, 2019

Faculty at participating institutions are invited to submit applications for BETRNet pilot projects of up to $40,000 to be funded by NIH/NCI U54CA163060: Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma by 11:59pm on January 31, 2019 with funding expected to begin May 1, 2019.

The specific aims of the pilot project award program are as follows:
  • To award pilot projects to enhance and extend the research goals and improve utilization of resources generated by BETRNet primary projects
  • To encourage innovative transdisciplinary approaches to increase understanding and develop intervention strategies focused on improving outcomes in patients with BE and EAC; and
  • To obtain preliminary data to enable generation of proposals to be successfully complete for funding at the national level.
A BETRNet Project must be directed toward translational research  related to Barrett's Esophagus. At least one specific aim should involve either direct patient contact or the study of patient-derived tissue samples. Questions about this request for applications can be directed to BETRNetAdmin@case.edu.
IN THE NEWS
Cleveland.com - Oct 24, 2018
Virtual and mixed reality are being used for simulation training that enhances traditional medical school training. A virtual reality anatomy lab, outfitted with laptops, joysticks and headsets for high-tech learning, will be inside the Sheila and Eric Samson Pavilion, the centerpiece of a new $515 million health education campus shared by the Cleveland Clinic and Case Western Reserve University when it opens in 2019.

NIH BULLETIN - Notices and Funding Opportunities
Notices
NIH to Host Second Informational Webinar on Proposed Key Provisions for a Future Draft Data Management and Sharing Policy

NCI Request for Information (RFI): Input to Advance Computational Approaches in Cancer Prevention Science

Request for Proposals (RFP) N01CN87006-18 "PREVENT Cancer Preclinical Drug Development Program: cGMP Production of Vaccines and Biologicals for Cancer Prevention"

Request for Applications
 
Program Announcements
IN THIS ISSUE
EVENTSevents
Fri, Nov 23
Case Western Reserve University Closed
Mon, Nov 26
Cleveland Clinic Genomic Medicine Institute
Madhav Sankunny, PhD
"Identification of potential NLS and NES on KLLN suggests nuclear and cytoplasmic functions"
12p NE1-205

Cancer Center Research Chalk Talk
1p WRB 3-136
Tues, Nov 27
Thurs, Nov 29
Developmental Therapeutics Journal Club
9a R4-013

Molecular Biology and Microbiology Seminar
Emma Schroder and Hyunkeun Kim
Rietsch Lab, CWRU
1p SOM W203
Fri, Nov 30
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series Guest Speaker
Alex G. Waterson, PhD Director, Scientific Coordinator, Vanderbilt Center for Cancer Drug Discovery Research Associate Professor, Pharmacology Research Associate Professor, Chemistry 
Vanderbilt University
"Discovery and characterization of cell active inhibitors of Lactate Dehydrogenase (LDH) using structure-based design"
12p WRB Auditorium
Mon, Dec 3
Tumor Immunology and Immunotherapy Meeting:  Defne Batik Watson
4p WRB 1422D
Tues, Dec 4
Cancer Center Research in Progress Seminar
3p WRB 3136
Thurs, Dec 5
Developmental Therapeutics Journal Club
9a R4-013

Molecular Biology and Microbiology Seminar
Marie McCausland and Braulio Llorens
Levine lab, CWRU
1p SOM W203

Prostate Cancer Working Group Seminar Series & Journal Club
"Prostate cancer - a translational pathology approach"
Michael Haffner, MD, PhD
3p NE1-205
Fri, Dec 6
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series
Mohamed Abazeed, MD, PhD
Director, Center for Precision Radiotherapy
Department of Radiation Oncology
Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine
"On prediction in complex systems"
12p WRB Auditorium
ADDITIONAL UPCOMING SYMPOSIUMS & EVENTS
prev-funding
PREVIOUSLY ANNOUNCED OPPORTUNITIES

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center