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November 9, 2018
MEMBER/CENTER HIGHLIGHTS
Newly Created Training Program Aims to Spark Undergraduate Interest in Cancer Research
The  Case Comprehensive Cancer Center (Case CCC has been awarded a five-year,  $1.6 million grant  from the National Cancer Institute to fund a newly created program that will  engage undergraduate scholars in cancer research. The Cancer-focused Summer Undergraduate Research program  (CanSUR ) will be led by  Mark Jackson, PhD , associate director for training and education for the Case CCC.  

As a comprehensive cancer center, one of the Case
Mark Jackson, PhD CCC's main objectives is to educate the next generation of cancer researchers. The Center has recognized an opportunity to leverage our membership to facilitate a formal mentoring experience specifically focused on undergraduates.  "With CanSUR we have the opportunity to better connect with highly-motivated undergraduates and actively foster their excitement about a career in cancer research," said Jackson who is also professor of pathology, Case Western Reserve University. Jackson said CanSUR plans to welcome 32 undergraduates per year for a 10-week experience, with a goal to increase undergraduate involvement to 160 over five years.

The program's structure will be very hands-on, offering a unique and immersive experience for program participants, said Damian Junk, PhD, assistant director of cancer training and education for the Case CCC. CanSUR will begin with a week-long "cancer research bootcamp ," which will include lectures on cancer biology, seminars about cancer career paths, facility tours, laboratory safety training, and social events. Mentored research, scientific enrichment and career path programming will take place over the remaining 9 weeks.

Selected scholars will receive a $4000 stipend for the summer and additional housing and travel allowances are available for up to 12 participants.  Undergraduates from across the country are encouraged to apply. Applications for the program are expected to open early December 2018. more>
Cross-Disciplinary Team Led by Sharifi Secures $1M Prostate Cancer Foundation (PCF) VAlor Challenge Award 
A team of investigators led by Nima Sharifi, MD,   GU Malignancies Program Leader,  Case
Dr. Nima Sharifi
Comprehensive  Cancer Center, h ave  been awarded the 2018  Mizel Family Foundation PCF VAlor Challenge Award  for their project " Therapeutic reversal of a metabolic mechanism that drives prostate cancer resistance to AR antagonists." This is the second time in four years that he has received the highly competitive grant.  The group is developing novel treatments to target androgen & glucocorticoid receptors to prevent castration-resistant prostate cancer.  Also from the Case Comprehensive Cancer Center were co-investigators  Eric Klein, MD and Jorge Garcia, MD . more>
Zhao Awarded $200K to Investigate the MALAT1 Gene's Potential to Treat/Prevent Multiple Myeloma
Case Comprehensive Cancer Center member Jianjun Zhao, MD, PhD  has received a  2-year, 
Jianjun Zhao 2
$200K  grant to fund his studies of  the  viabi lity of targeting the the metastasis-associated lung adenocarcinoma transcript 1  (MALAT1) gene for prevention or treatment of multiple myeloma. The grant is awarded by the V Foundation, founded by ESPN and the late Jim Valvano, famous basketball coach and commentator.
"My team is working to investigate how this mechanism contributes to the onset and progression of the disease, as we believe MALAT1 levels may serve as a predictor of multiple myeloma," said Zhao. more>
Cancer Disparities Pilot Awardees Announced
The Office of Cancer Disparities Research of the Case Comprehensive Cancer Center 
Monica Webb Hooper has made pilot award selections following a recent RFA. The awards are an effort to stimulate research designed to both improve understanding of contributing factors to cancer disparities as well as develop and test interventions for reducing and ultimately eliminating them. Selected disparities-focused projects were recognized as highly innovative and impactful, and likely to generate key data for larger, nationally competitive grants. Each project will be granted $50,000 in seed funding.

A team led by  Monica Webb Hooper,
PhD was chosen to investigate 
Stefanie Avril
" Innovations to Prevent Relapse among Low-Income African American Smokers."  Also selected to receive funding was  " Functional Immune-Phenotypes underlying Racial Disparities in Endometrial Cancer" to be examined by Stefanie Avril, MD. more>
Post-doc Scholar: Department Surgery UH
A highly translational lab led by the Chief of Surgical Oncology, with NCI funding in place for the next 7 years, is inviting applications for a post-doc scholar. Focused on helping  to solve pancreatic cancer, the post-doc will work closely with the PI plan and execute experiments.   The lab works closely with other PIs at the Case Comprehensive Cancer Center , as well as clinical departments at University Hospitals including collaborations with a multidisciplinary team of biologists, statisticians, and clinicians. more>
MARK YOUR CALENDARS
Cancer Center Seminar Series: "Cancer research in an integrated health care setting"
Nov 9, 12p | WRB Auditorium

Lawrence Kushi Join us Friday, November 9 at 12p in the WRB Auditorium to hear Dr. Lawrence Kushi, ScD present " Cancer research in an integrated health care setting. Dr. Kushi is Director of Scientific Policy, Division of Research at Kaiser Permanente .

Larry is a nutritional epidemiologist whose research projects include the Pathways Study,
examining multiple factors in breast cancer outcomes; the Be-Well Study, examining diet and bladder
cancer recurrence; and the Cancer Research Network, supporting cancer research in a consortium of health  care systems.

A graduate of Amherst College and the Harvard School of Public Health, Dr. Kushi was on the faculty at the
University of Minnesota and Columbia University before joining Kaiser Permanente in 2002.
3rd Annual Cancer Disparities Symposium
Mar 1, 2019 | Tinkham Veale University Center
Disparities Banner 2019-final
The 3rd Annual Cancer Disparities Symposium will be held Friday, Mar 1, 2019. 

2019 Symposium Highlights
  • Keynote presentations by renowned disparities researchers and community leaders
    • Opening Keynote by Eliseo J. Pérez-Stable, MD, Director of the National Institute on Minority Health and Health Disparities (NIMHD), National Institutes of Health (NIH)
    • Scientific Keynote presentation by Rick Kittles, PhDAssociate Director of Health Equities, Comprehensive Cancer Center; Professor and Director, Division of Health Equities, Department of Population Sciences, City of Hope
  • Oral and Lightning presentations from selected abstracts
  • Poster session highlighting academic research and community programs
  • Networking session
  • All attendee forum
Call for Abstracts

The Case Comprehensive Cancer Center invites multidisciplinary researchers, community agencies and organizations to submit abstracts for presentation at the 3rd Annual Cancer Disparities Symposium. Abstracts will be divided into two tracks: Scientific Research and Community Programs. Meritorious abstracts will be selected for oral presentations. 

**Students who submit an abstract are able to register for FREE! Submit your abstract to  caseccc-ocdr@case.edu   BEFORE  registering. You will be emailed a discount code to be entered on the registration form so that you receive the discount. 

Abstracts must be submitted via email ( caseccc-ocdr@case.edu) by 5pm EST on December 21, 2018.

Registration

Registration is now OPEN for this symposium.  
Click here for registration information.
FUNDING OPPORTUNITIES
2019 Cancer Prevention Laurels Awards
Deadline: Dec 17, 2018

Prevent Cancer Foundation
The Prevent Cancer Foundation has opened nominations for the  2019 Cancer Prevention Laurels Awards. Since 2003, the Laurels Awards have recognized and celebrated innovators and leaders in the fight against cancer.

Nominations are accepted for people who have made exceptional contributions in the following categories:
  • National Leadership
  • Increasing Health Equity
  • Dedication to Community Service
IN THE NEWS
CWRU's The Daily - Sep 20, 2018
Among six projects selected were those led by  Case Comprehensive Cancer Center members: Drs. Anant Madabhushi, Susann Brady-Kalnay, James Basilion, Mark Griswold, Brian Grimberg, and David Wilson.

Researchers Build "Mini-Colon" to Study Inflammatory Bowel Disease, Cancer
Lerner Research Institute - Oct 12, 2018
Embedding epithelial cells from biopsied patient colons in a gel matrix, Emina Huang, MD, Case Comprehensive Cancer Center, and her team cultivated them to create a three-dimensional organoid, or "mini-colon." The model can be used to study processes related to ulcerative colitis and colorectal cancer.

Genomic Breakthroughs Offer Hope for New Strategies in AML
OncLive - Oct 23, 2018
A study shows mutations in 8 high-risk genes are associated with an acute myeloid leukemia diagnosis. Hetty Carraway, MD, Case Comprehensive Cancer Center, provided insight on the prevalence of actionable mutations as well as the research and therapies surrounding ALM.
NIH BULLETIN - Notices and Funding Opportunities
Request for Applications

Program Announcements

 
IN THIS ISSUE
EVENTSevents
Fri, Nov 9
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series Guest Speaker
Lawrence H. Kushi, ScD Director of Scientific Policy Division of Research Kaiser Permanente
"Cancer research in an integrated health care setting"
12p WRB Auditorium
Mon, Nov 12
Shared Resources Directors Meeting
12p WRB 1422D
Tues, Nov 13
Cancer Impact Lecture
Stanley Adoro, PhD Assistant Professor of Pathology, CWRU
1p NE1-205 Cleveland Clinic
Weds, Nov 14
PRCHN Seminar
Dana Prince, PhD, MPH
Assistant Professor, Jack, Joseph, and Morton Mandel School of Applied Social Sciences, CWRU
"Community-grounded research to address mental health disparities of sexual and gender minority youth touched by foster care"
Thurs, Nov 15
Developmental Therapeutics Journal Club
9a R4-013

Molecular Biology and Microbiology Seminar
1p SOM W203

Cell Therapy Translational Seminar
Drs. James Chmiel and Tracey Bonfield  will discuss the journey which led to utilizing hMSCs in patients with cystic fibrosis for the "First in CF" trial. 
3p WRB 2-136
Fri, Nov 16
Taussig Cancer Institute Grand Rounds
8a CA5-120

Cancer Center Seminar Series 
Khalid Sossey-Alaoui, PhD
Assistant Professor, Molecular Medicine, Cleveland Clinic Lerner College of Medicine
Researcher, Molecular Cardiology Cleveland Clinic
Member, Molecular Oncology Program, Case CCC
"Regulation of the tumor microenvironment by Kindlin-2 in breast cancer"
12p WRB Auditorium
Mon, Nov 19
Genomic Medicine Institute & Quantitative Health Sciences
Aarno Palotie, MD, PhD
Professor, Research Director, Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Finland
Massachusetts General Hospital and Broad Institute of MIT and Harvard, Boston
"Using population isolates and nordic health care data in disease"

Cancer Center Research Chalk Talk
1p WRB 3-136

Cancer Center Junior Faculty Meeting
2p WRB 1422D

Wolstein Research Building Faculty Meetings with Stan Gerson
3:30p WRB

Tumor Immunology and Immunotherapy Meeting: Sharma and Distelhorst
4p CA5-124
Tues, Nov 20
Cancer Impact Lecture
Robin Parihar, MD, PhD Assistant Professor of Pediatrics, Baylor College of Medicine

ADDITIONAL UPCOMING SYMPOSIUMS & EVENTS
prev-funding
PREVIOUSLY ANNOUNCED OPPORTUNITIES

Deadline: Open

Deadline: Open

Deadline: Open
Case Comprehensive Cancer Center