OCTOBER 18, 2019
Message from the Director
Stan Gerson, MD
Director, Case Comprehensive Cancer Center
Administration Leadership Update
Dear members of the Case Comprehensive Cancer Center community:

I am happy to announce that John Pounardjian, MBA has been appointed Associate Director of Administration at our exceptional center.

This appointment comes after an extensive national search following the departure of former Associate Director for Administration Megan Kilbane this past March. John served as Acting Associate Director of Administration in the interim, from his role as Deputy Associate Director.

John was an integral part of our last renewal, and has quickly risen as an exceptional CCSG administrator, serving on national cancer center administrator committees and advising other designated cancer center administrative teams. He already coordinates many pilot grant awards, shared resources, and all of our meetings with his administrative team.
John Pounardjian
John has been a member of the Case CCC Admin team since 2012, previously serving as GI SPORE Administrator. 

Please join me in wishing John continued success in his new role.
Member/Center Highlights
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Alumni of YES Program at Case CCC Earns Medal for Gene Mutation Research
For the past three years, the National Cancer Institute has funded the Youth Engaged in Science (YES) program at Case Western Reserve University (CWRU), introducing and training underrepresented minorities to cancer care and research professions. The program is led by Nathan Berger, MD.

Program alumni Connor Harris, earned a bronze medal this past summer at the NAACP Afro-Academic, Cultural, Technological and Scientific Olympics for his project with CWRU scientists studying the mutation of the EPHA6 gene protein.Throughout the project, Connor was mentored by Kishore Guda, DVM, PhD. Congratulations, Connor!
Shuttle Service between CWRU and the HEC, Cleveland Clinic
As temperatures in Cleveland drop and meetings are held in various locations across our institutions, we want you to be aware of two free shuttle routes to and from Case Western Reserve University and the Health Education Campus (HEC), steps away from Cleveland Clinic.

Headed to our weekly seminar series? The Wolstein Research Building is only a 6 minute shuttle ride from the Health Education Campus (HEC) to the Cornell stop on the HEC Main Shuttle!

Making your way to the Immuno-Oncology Seminar in the NE Building at Cleveland Clinic? Both HEC shuttles drop off at the HEC on E 100th St. Walk south on E 100th St, crossing Euclid and Carnegie Aves, and turn right on Carnegie (heading east) toward East 96th St. Make a left on 96th, walking straight to the main door of the NE Building. The conference room is to the right inside the entrance. Note: this main entrance is locked, but someone will be at the door to let you in for this meeting.
"Co-evolution of Malignant and Immune Cells in High Grade Serous Ovarian Cancer"
Don't miss your chance to hear from Sohrab Shah, PhD, Chief of Computational Oncology at Memorial Sloan Kettering Cancer Center at the Artificial Intelligence in Oncology Symposium next Thursday, October 24!
What's Coming Up
Mark Your Calendar
Cancer Center Seminar Series
October 18, 12p
WRB 3-136

Today's seminar will feature Amar Desai, PhD presenting, "15-PDGH Mediated Regeneration Following Hematopoietic Stem Cell Transplantation" at noon in WRB conference room 3-136.

Amar Desai is an assistant professor in the Case Comprehensive Cancer Center at Case Western Reserve University where his lab is interested in elucidating mechanisms of tissue regeneration within the bone marrow microenvironment. In 2017, Dr. Desai received the prestigious NIH K99/R00 Pathway to Independence Award and in July 2019, started his independent research group within the Case CCC. His lab continues to characterize the efficacy of 15-PGDH inhibitors in promoting hematopoietic recovery in preclinical models of transplantation, in addition to exploring mechanisms of pathogenesis for additional hematopoietic malignancies including graft versus host disease and bone marrow failure disorders. The overall goal of the Desai lab is to develop novel therapeutics capable of reducing morbidity, mortality, and expense of human hematopoietic stem cell transplantation - making the procedure safer, faster and more affordable.
Artificial Intelligence in Oncology Symposium
October 24, 2019
Tinkham Veale University Center

The Case Comprehensive Cancer Center and Center for Computational Imaging and Personalized Diagnostics at Case Western Reserve University (CWRU) will host the inaugural  Artificial Intelligence in Oncology Symposium : Advancements in Policy at CWRU on Thursday, October 24, 2019.

We're bringing together experts in AI and machine learning as well as clinical, industry and federal agency experts in pathology, radiology, oncology and immuno-oncology to speak on research developments, regulatory policy, reimbursement and ethics surrounding AI.

Symposium Highlights:
  • Focused panel discussions
  • Networking opportunities
  • Exhibitions available throughout the day

  • Sohrab Shah, PhD, Chief, Computational Oncology, Memorial Sloan Kettering Cancer Center

Seats are filling quickly, so don't wait!  A discount for students and trainees who wish to attend is available. We look forward to seeing you there!
Cancer Center Seminar Series
October 25, 12p
WRB Auditorium

Next week's seminar will return to the WRB Auditorium and feature Alok Khorana, MD presenting, "Cancer-Associated Thrombosis: Mechanisms, Prevention and Treatment " at noon.

Alok Khorana is Vice-Chair, Clinical Services at Taussig Cancer Institute, Director of the GI Malignancies Program, and professor of medicine at the Lerner College of Medicine, Cleveland Clinic. Dr. Khorana is also a member of the Case CCC's Developmental Therapeutics Program.

His clinical and translational research program focuses on predictive factors and drug development in cancer-associated thrombosis and gastrointestinal cancers.
NCRM logo
NCRM Special Seminar
November 5, 12p
WRB 3-136

The National Center for Regenerative Medicine (NCRM) is hosting a special seminar on Tuesday, November 5 at 12p in WRB conference room 3-136 featuring David Dean, PhD.

Dr. Dean is associate professor of plastic surgery at The Ohio State University and Member of The Center for Regenerative Medicine and Cell-Based Therapies.

Dr. Dean's research has led to the development of computer-aided design software for the additive manufacture, also referred to as 3D printing, of tissue-engineered bone implants. His research program currently includes the seeding of bone marrow-derived mesenchymal stem cells in 3D printed bone tissue engineering scaffolds. These scaffolds are bioreactor pre-cultured prior to implantation. Much of this research has focused on the repair of critical size and larger cranial defects.
CWRU SOM logo - png
Dale H. Cowan, MD-Ruth Goodman Blum Cancer Research Professorship Program and Reception
November 5, 4:30p
Wolstein Research Building
A program and reception celebrating the appointment of Zhenghe John Wang, PhD as the Dale H. Cowan, MD-Ruth Goodman Blum Professor of Cancer Research will be held on Tuesday, November 5 at 4:30 pm in the Wolstein Research Building.

Complementary valet parking will be available on Circle drive between Mayfield and Cornell Roads.

Please RSVP to Barbara Nicol Waltermire by Tuesday, October 29, 2019 if you wish to attend.
Innovators in AYA Cancer Symposium
November 14-15, 2019
Tinkham Veale University Center

The Angie Fowler Adolescent and Young Adult (AYA) Cancer Research Initiative of the Case Comprehensive Cancer Center invites you to attend Innovators in AYA Cancer: Driving Science and Policy toward a Brighter Future for Teens and Young Adults with Cancer this November at Case Western Reserve University.

Call for Abstracts Deadline Extended
The Symposium will feature a poster session and Rising Star oral presentations. All students, postdocs, residents, fellows and faculty conducting research in AYA cancer are invited to submit abstracts. Monetary prizes will be awarded. Abstracts must be submitted electronically by Friday, November 1, 2019 at 5pm ET. Learn more>

Register today to save your seat!  A discount for students and trainees who wish to attend is available. We look forward to seeing you in November!
2019 Clinical Research Retreat
November 21, 5-7p
Taussig Cancer Center CA5-120

The Case Comprehensive Cancer Center will host the Clinical Research Retreat, a semi-annual showcase of clinical cancer research across our institutions from 5-7 pm on Thursday, November 21 at Cleveland Clinic Taussig Cancer Institute, CA5-120.

The evening's agenda is focused on two timely and exciting areas of cancer clinical research. First, attendees will hear from current NCI K12 Paul Calabresi Scholars, Molly Gallogly, Roberto Vargas, Kristen VanHeyst and Haider Mahdi who will discuss their innovative investigator initiated treatment (IIT) protocol that is based on preclinical models. Since development of an exciting IIT protocol takes a village, your feedback will be important.

Secondly, Charles Kunos, MD, PhD, a clinical investigator and protocol reviewer at CTEP, NCI will deliver his keynote address, "Engaging CTEP in early phase radiopharmaceutical trials" updating us on innovative approaches to evaluate this drug class. Dr. Kunos is a graduate of our long-standing K12 program and was a member of the Case CCC before moving on to the NCI.

Validated parking is available at 2101 East 100th St, Cleveland, OH 44106.
4th Annual Cancer Disparities Symposium
March 6, 2020
Tinkham Veale University Center

The Case Comprehensive Cancer Center Office of Cancer Disparities Research will present the   4th Annual Cancer Disparities Symposium : Cultivating Science and Community Engagement to Address Cancer Health Disparities on March 6, 2020. 

The symposium will feature keynote presentations by renowned disparities researchers and community leaders, a poster session highlighting academic research and community programs, networking opportunities and an interactive panel discussion.

Call for Abstracts
The   4th Annual Cancer Disparities Symposium is a premier event for presenting cutting-edge cancer disparities science and related community programs and services. The Office of Cancer Disparities Research will divide abstracts into two tracks:   Scientific Research   and   Community Programs and Services . Scientific Research abstracts are encouraged from multidisciplinary researchers that are focused on various aspects of health disparities and/or community-focused science. Community programs and service abstracts are encouraged from organizations that provide programs and services that benefit the community. Meritorious abstracts will be selected for oral presentation.  Abstracts must be submitted electronically by 5p EST on Tuesday, December 3, 2019. Students who submit an abstract prior to registration are able to register for free!   Learn more>
Additional Upcoming Events
Cleveland Clinic Best of Radiation Oncology 2019
November 9, 2019
Independence, OH
Cleveland Clinic Breast Cancer Update: From Detection Through Treatment to Survivorship
November 13, 2019
Independence, OH
Cleveland Clinic Children's Pediatric Lecture Series
November 25, 8a
Cleveland Clinic R3-002/003
Join Cleveland Clinic Children's for "The Science of Pediatric Blood & Cancer" Lecture Series featuring Gregory H. Reaman, MD presenting, "Pediatric Cancer Drug Development: The Road Well Traveled by the Therapeutic Orphans - Construction Ahead."
NCCN 2020 Annual Conference
March 20-22, 2020
Orlando, FL
Abstract submission for the General Poster Session is open through Wednesday, October 23, 2019.
Funding Opportunities
Case Comprehensive Cancer Center Funding Opportunities - Deadlines Extended

Please note the Case CCC has extended deadlines for the following awards:

Deadline: Friday, Nov 8, 2019

Deadline: Friday, Nov 8, 2019

Deadline: Friday, Nov 8, 2019
LOI Deadline: November 18

The Case Comprehensive Cancer Center, with funds from its Outstanding-rated American Cancer Society Institutional Research Grant, will provide seed money to foster cancer research by junior faculty who have no current national grant support of their own. Investigators in the CWRU School of Medicine, University Hospitals of Cleveland and Cleveland Clinic Lerner College of Medicine as well as in other schools and colleges affiliated with Case Western Reserve University are eligible. Grants for cancer-related research, not to exceed $30,000, will be awarded to investigators who intend to gather preliminary data to be used in seeking future and independently funded programs. A portion of ACS IRG funds is set aside for special interest awards in adolescent and young adult (AYA) cancers.
In The News
ASCO Daily News - Sept 25, 2019
Check out this Q & A with Anant Madabhushi, PhD prior to his keynote lecture at ASCO's Breakthrough Summit in Bangkok last week where he shares the value of Artificial Intelligence in Oncology.
Cleveland Clinic Catalyst - Oct 2019
Charis Eng, MD, PhD, Chair and inaugural Director of Cleveland Clinic’s Genomic Medicine Institute, has been a pioneer in her field for decades.
HemOnc Today - Oct 10, 2019
The social media landscape is changing constantly and influencing all realms of society - and health care is no exception. Cleveland Clinic Hematologist-Oncologist and Case CCC member Aaron Gerds, MD, MS, comments on Twitter's popularity among medical professionals.
ABC News 5 Cleveland - October 16, 2019
As of October 17, the legal age to purchase tobacco products in Ohio has raised from 18 to 21. Tobacco research expert and Co-Leader of the Case CCC's Cancer Prevention, Control & Population Research Program, Erika Trapl, PhD, weighs in.
From The NIH
Weekly NIH Funding Opportunities and Notices
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