Message from the Director
Dr. Stan Gerson
Stan Gerson, MD
Director, Case Comprehensive Cancer Center
Something for Everyone
The National Cancer Institute's annual plan and budget proposal was recently released and it has something for everyone - that is, everyone interested in better cancer care outcomes through cancer research. The NCI report outlines the public face for the NCI and how they present their priorities to congress. In fact, this becomes the Bible for congressional staff, NCI PR and the elevator speech of NCI Leadership.

While this report does not really provide a clue about where the next RFA and investments are coming, being knowledgeable about what they are thinking is important.

Often, our research is featured in this report, but not this year. Still, there are many points of note:
  1. Implementation science has come into its own, and even our basic science mechanism investigators can consider how to best implement impact of their research; even more so for our investigators focused on reducing risks - obesity, smoking, exposures, stress and investigating family risk and genomic issues linked to that risk, as well as recurrent epigenetic changes. For us, we would like to have implementation efforts for our genomics efforts.
  2. A strong appreciation that the R01 pool be funded at the 15% payline up from the current 8%. Let's hope this can be eventuated.
  3. The NCI is proud of their support for the broad pool of education in cancer research. This is a clear shift from the varmus years and correctly reflects the incredible needs to develop high-powered next-generation cancer investigators.
  4. Attention to the world cancer burden and encouragement of international cancer research, especially in population cancer research.
  5. Please note that a priority area is artificial intelligence (AI) with leadership in our scientific computational diagnostics scientific initiative led by Anant Madabhushi.

Please look this over and take from it your talking points. Understanding the NCI will help in your next application!

Member/Center Highlights
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American Society for Radiation Oncology Annual Meeting 2019: Highlights from the Case CCC
The 2019 American Society of Radiation Oncology (ASTRO)  Annual Meeting  will take place Sunday, September 15 through Wednesday, September 18, 2019 at McCormick Place West in Chicago, IL. ASTRO offers interactive sessions with content curated by specialty, purposeful networking opportunities, facilitated break-out sessions and discussion time to allow attendees to engage in multidisciplinary collaboration.

The Case Comprehensive Cancer Center (Case CCC) has  compiled a list  of speakers, poster presentations, session moderators and discussants from Cleveland-based institutions including Cleveland Clinic, University Hospitals Cleveland Medical Center and Case Western Reserve University. We wish the best of luck to all presenters and attendees and safe travels to Chicago!
Madabhushi named to The Pathologist's 2019 Power List
100 of the industry's trailblazers were recently named to The Pathologist's 2019 Power List following reader nominations and expert panel judging. This year's list includes Anant Madabhushi, PhD, Director of the Center for Computational Imaging and Personalized Diagnostics at Case Western Reserve University. His multidisciplinary work spans projects in quantitative image analysis, computer-aided diagnostics, pattern recognition and more. The findings have allowed for machine learning methods that better predict which lung cancer patients will benefit from chemotherapy. Madabhushi is also a member of the Case CCC's Cancer Imaging Program and Chair of the Planning Committee for this October's Artificial Intelligence in Oncology Symposium.
Yu elected to Society of Neuro-Oncology Board of Directors
The Case Comprehensive Cancer Center extends congratulations to Jennifer Yu, MD, PhD on her recent election to the Society of Neuro-Oncology Board of Directors as radiation oncology representative.

Yu is staff at Cleveland Clinic Center for Cancer Stem Cell Research. She is also associate professor of molecular medicine at CWRU School of Medicine and member of the Case CCC ’s Molecular Oncology Program. 
CanSUR Program Seeking Mentors for Summer 2020
The Cancer-focused Summer Undergraduate Research (CanSUR) Program supports 32 undergraduates for a 10-week period (June through August) each summer, as of summer 2019 . The goal of the program is to generate excitement for a future career in cancer research in highly motivated undergraduates and help them prepare for the next stage of their careers.

Cancer Center members who wish to volunteer as mentors for the 2020 program or are interested in hosting additional students next year are encouraged to contact Gena Richmann at .
What's Coming Up
Mark Your Calendar
Cancer Center Special Seminar
September 12, 1p
WRB 2-136

All are welcome to hear from  Jennifer Cullen, PhD, MPH  on Thursday, September 12 at 4 pm in the Wolstein Research Building Conference Room 2-136. Dr. Cullen is the Interim Co-Director of the Center for Prostate Disease Research (CPDR) - a supported program of the Henry M. Jackson Foundation for the Advancement of Military Medicine. She is also Director, Epidemiologic Research at the CPDR and associate research professor of surgery at the Uniformed Services University of the Health Sciences (USUHS). Dr. Cullen will present, "Leveraging a Racially Diverse, Military Cohort to Address Health Disparities in Prostate Cancer Outcomes, 1990-2017."
Cancer Center Seminar Series
September 13, 12p
WRB Auditorium

Our interdisciplinary seminar series addresses cutting-edge clinical, translational, and basic research topics in cancer. Held weekly on Fridays at 12 pm in the Wolstein Research Building Auditorium, 1-413, attendees are able to interact with our speakers and receive CME credit for the educational activity.

Our series returns Friday, September 13, 2019 with Abhishek Chakraborty, PhD presenting, "Exploiting Dioxygenase Dysfunction to Target Cancer" on behalf of the GU Malignancies Program. Dr. Chakraborty is Assistant Staff, GU Malignancies Research Center at Cleveland Clinic Lerner Research Institute.

We look forward to seeing you each week as the academic year begins again.
Racial Equity Institute (REI) Groundwater Training
September 18, 5p-8p
Wolstein Research Building
Researchers and clinicians are invited to join the Case CCC Office of Cancer Disparities Research and the Prevention Research Center for Healthy Neighborhoods (PRCHN) for a learning journey to increase shared understanding of racial inequities that impact health, and to discuss strategies to promote a more equitable society.

  • Inform your catchment area, disparities and/or community-based research
  • Learn how structures (e.g., healthcare, education) lead to inequities
  • Build better community-academic collaborations
  • Improve patient and community engagement
  • Be a part of our institutional transformation

This training is free to attend, but registration is required. Dinner will be provided. Use password CWRU to register below.
MetroHealth logo
MetroHealth Cancer Care Symposium
September 20, 1-5p
MetroHealth Medical Center, R170

Join the MetroHealth System on Friday, September 20 from 1-5 pm in the Rammelkamp Atrium, R170 for the 4th Annual Cancer Care Symposium, "Updates and Advancements in Radiation Therapy."

The agenda includes remarks from Director of the MetroHealth Cancer Center, Benjamin Li, MD, member of the Case CCC's Developmental Therapeutics Program as well as a presentation from David Mansur, MD, Director of Pediatric and Hematologic Radiation Oncology and Vice Chair for Proton Therapy at University Hospitals Seidman Cancer Center and member of the Case CCC Cancer Imaging Program.

Light refreshments will be provided. Registration is required.
Women's Cancers Initiative Mini-Retreat
September 28, 8a-1p
WRB Auditorium

Members: as the Case Comprehensive Cancer Center builds the Women's Cancers Initiative, a mini-retreat will be held Saturday, September 28 to identify investigators, projects and general themes of research strengths and interests.

Our goal is to be as comprehensive as possible to ensure that all aspects of Women's Cancers research being conducted in Cleveland are represented at the retreat and in the initiative. Additional information regarding the retreat structure will be available soon.
Pediatric Cancer Survivorship Symposium
September 28, 2019, 8a-3:30p
Cleveland Clinic Main Campus

Join Cleveland Clinic Children's for the Pediatric Cancer Survivorship Symposium Saturday, September 28, 2019 at Cleveland Clinic Main Campus.

The symposium will feature presentations on . using technology to stay healthy after treatment, future fertility, heart health, the financial impact of cancer treatment and upcoming directions in research for cancer survivorship.

A keynote address will be delivered by Tim Folse who will discuss the Primary Care Perspective on Caring for Cancer Survivors.

Please register for this free event via the button below. Patients may bring up to two guests each.

Questions may be directed to Jasmine Boutros at .
Colorectal Oncology Conference
October 18-19, 2019, 8a-3:30p
Naples, FL

The 6th Annual Multidisciplinary Colorectal Oncology Course will take place October 18-19, 2019 at Naples Beach Hotel & Golf Club in Naples, FL. The national symposium will focus on providing an in-depth and up-to-date review of the multidisciplinary management of colorectal cancers. Oncologists, surgeons, radiation oncologists and nurses with an interest in the management of patients with colorectal cancer should attend this course.

Various continuing education credits are available for the course. The deadline for registration is 5pm (PST), Sunday, October 13, 2019.
Early Bird Registration Extended: Artificial Intelligence in Oncology Symposium
October 24, 2019
Tinkham Veale University Center

The Case Comprehensive Cancer Center and Center for Computational Imaging and Personalized Diagnostics at Case Western Reserve University (CWRU) will host the inaugural  Artificial Intelligence in Oncology Symposium : Advancements in Policy at CWRU on Thursday, October 24, 2019.

The symposium will bring together experts in AI and machine learning as well as clinical, industry and federal agency experts in pathology, radiology, oncology and immuno-oncology to speak on research developments, regulatory policy, reimbursement and ethics surrounding AI.

Symposium Highlights:
  • Focused panel discussions
  • Networking opportunities
  • Exhibitions available throughout the day

  • Sohrab Shah, PhD, Chief, Computational Oncology, Memorial Sloan Kettering Cancer Center

Discounted early bird registration has been EXTENDED through Sunday, September 15.  A discount for students and trainees who wish to attend is available. We look forward to seeing you in October!
Breast Cancer Update: From Detection Through Treatment to Survivorship
November 13, 2019
Independence, OH

The Breast Cancer Update: From Detection Through Treatment to Survivorship will take place Wednesday, November 13, 2019 at the Embassy Suites Hotel in Independence, OH.

This regional symposium will focus on providing an in-depth and up-to-date review of the detection and management of breast cancer. Internal medicine, family medicine, general practice, oncologists, nurses, nurse practitioners, physician assistants and residents/fellows with an interest in the management of patients with breast cancer should attend this course.

Various continuing education credits are available for the course. The deadline for registration is 5pm (EST), Monday, November 11, 2019.
Early Bird Registration and Call for Abstracts: Innovators in AYA Cancer
November 14-15, 2019
Tinkham Veale University Center

The Angie Fowler Adolescent and Young Adult (AYA) Cancer Research Initiative of the Case Comprehensive Cancer Center invites you to attend Innovators in AYA Cancer: Driving Science and Policy toward a Brighter Future for Teens and Young Adults with Cancer this November at Case Western Reserve University.

Call for Abstracts
The Symposium will feature a poster session and Rising Star oral presentations. All students, postdocs, residents, fellows and faculty conducting research in AYA cancer are invited to submit abstracts. Monetary prizes will be awarded. Abstracts must be submitted electronically by Friday, October 18, 2019 at 5pm ET. Learn more>

Be sure to register by October 18, 2019 to secure our discounted early bird registration . A discount for students and trainees who wish to attend is available. We look forward to seeing you in November!
Save the Date: 4th Annual Cancer Disparities Symposium
March 6, 2020
Tinkham Veale University Center

The Case Comprehensive Cancer Center Office of Cancer Disparities Research will present the  4th Annual Cancer Disparities Symposium : Cultivating Science and Community Engagement to Address Cancer Health Disparities on March 6, 2020. 

The symposium will feature keynote presentations by renowned disparities
researchers and community leaders, a poster session highlighting academic research and community programs, networking session and an all-attendee forum.

Call for Abstracts
The  4th Annual Cancer Disparities Symposium  is a premier event for presenting cutting-edge cancer disparities science and related community programs and services. The Office of Cancer Disparities Research will divide abstracts into two tracks:  Scientific Research  and  Community Programs and Services . Scientific Research abstracts are encouraged from multidisciplinary researchers that are focused on various aspects of health disparities and/or community-focused science. Community programs and service abstracts are encouraged from organizations that provide programs and services that benefit the community. Meritorious abstracts will be selected for oral presentation.  Abstracts must be submitted electronically by 5 pm EST on Tuesday, December 3, 2019.   Learn more>

Further registration details will be released soon!
Funding Opportunities
LOI Deadline: September 25
In The News
Technology Networks - Sept 4
A new study looking at incidence of disease data nationwide from 2000 to 2016 found a shift in obesity-associated cancers (OACs) to younger individuals. The team includes Case CCC members Siran Koroukian, PhD and Nathan Berger, MD .
Targeted Oncology - Aug 30
Results of a Phase I/II trial recently published in Clinical Cancer Research for patients with relapsed/refractory acute myeloid leukemia are encouraging. The cross-institutional team led by Anjali Advani, MD includes a number of Case CCC members.
From The NIH
Weekly NIH Funding Opportunities and Notices
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