The Open Science Data Repository Download

Year in Review 2023

Happy New Year! We've had a busy 2023. With the start of a new year, we wanted to highlight some of the amazing work that the Open Science Data Repository team has accomplished in 2023. So come check it out!

AWG Workshop

The Open Science Data Repository (OSDR) team held the 2023 Analysis Working Group (AWG) Workshop at the Capital Hilton in advance of the ASGSR 2023 conference. The workshop was attended by ~125 AWG members both in person and virtually and allowed the AWG community an opportunity to connect in person for the first time since the pandemic started. The workshop was organized into three sessions with a keynote address.

Session 1 focused on collecting feedback from the AWG community on user acceptance on current OSDR development within four specific topics. Listen to Session 1 presentations.

A keynote address had preceded session 2, which was delivered by Keith Siew and presented an insider's perspective into his space nephrology sample and data selection process. It provided insights into how the idea evolved through collaborative efforts and the utilization of resources available within the AWG network and OSDR. Listen to the Keynote Address.

To close off the event, session 3 provided the AWG leads an opportunity to open dialogue within each AWG about their community’s future, how to meet the objectives of the 2023-2032 Decadal Survey, and to develop new projects/collaborations. The leads of the six AWGs provided concise 5-min overview presentations. Listen to Session 3 presentations.

A total of 8 OSDR-enabled publications rocked the space science scene in 2023. Dive into the publications list on the OSDR website to catch up on the stellar stories, and don't miss the latest three that just dropped!

American Geophysical Union (AGU) Hyperwall Talk

Want a quick peek into the latest developments from OSDR? Then check out this latest video from Sylvain Costes presenting a hyperwall talk at AGU titled “Unveiling the Frontier: Open Science and the Future of Space Biology for Human Exploration." This presentation offered a comprehensive exploration of studies conducted with model organisms on the International Space Station (ISS) and explained the pivotal components of the OSDR.

OSDR Team Hosts Two Workshops at American Geophysical Union (AGU)

The OSDR team held two workshops during the AGU 2023 conference. On December 10^th, Amanda Saravia-Butler in collaboration with the National Microbiome Data Collaborative (NMDC) Team moderated the “Enabling Open and Interoperable Science: Multi-Omics Data Processing with Standardized Bioinformatics Workflows for Earth and Space Research” pre-conference half-day workshop. Sylvain Costes and Ryan Scott also supported this workshop. This hands-on learning workshop was designed for individuals eager to delve into the intricacies of multi-omics data processing and master the execution of standardized bioinformatics workflows, thus advancing the practice of open science by enabling data interoperability through these open-source platforms and by promoting the reuse of openly available data.

On December 15^th, Amanda Saravia-Butler, in collaboration with the NMDC team, moderated an innovation session titled “FAIR and Beyond: Ensuring the Future of Findable, Accessible, Interoperable, and Reusable (FAIR) Multi-Omics Data for all Stages of the Sample and Data Lifecycle to Enable Earth and Space Science Innovation and Discovery.” Sylvain Costes, Lauren Sanders, Ryan Scott and James Casaletto also supported this session including two panel discussions. This session discussed the entire sample and data lifecycle and provided novel tools and recommendations for ensuring data is as FAIR as possible. This session showcased NASA GeneLab’s and the NMDC’s capabilities and included open discussions, hands-on activities, and brainstorming the future of FAIR data.

New Series - Success Stories

Welcome to the “Open Science Success Stories”. These short narratives showcase insights garnered from interviews with members of the AWG community who have utilized Open Science datasets as a catalyst for advancing their careers in the field of space biology. Listen to the two newest interviews with Dr Willian Da Silveira of Staffordshire University and Kimberly Washington of Deep Space Bio.

Latest GeneLab Chats

Check out the latest releases of GeneLab Chats on our YouTube channel!

Dr Geraldine Vitry - Muscle atrophy phenotype gene expression during spaceflight is linked to a metabolic crosstalk in both the liver and the muscle in mice

Dr Jian Yang - Designing a Novel Monitoring Approach for the Effects of Space Travel on Astronauts’ Health

Dr Angela Relogio - Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent

Dr Ryo Fujita - Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination

Dr Chandran Sabanayagam - Transcriptomic Signature of the Simulated Microgravity Response in Caenorhabditis elegans and Comparison to Spaceflight Experiments

Dr Richard Barker - Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome

OSDR Summer Students

This summer, Open Science hosted eight summer students—James Rohde, Joanne Thomson, Liam Johnson, Nova Butte, Tasneem Nora Khokhar, Justin Davis, Vishnu Prasad, and Harlan Phillips. The summer students worked on a variety of tasks including standardizing metadata from bioimaging file formats, processing spaceflight datasets as input to the SPOKE biomedical knowledge graph, identifying patterns in microbial response to changes in environmental CO2, creating a metadata visualization dashboard to capture an overview of the studies within the OSDR, working in Science Communications to help expand OSDR’s social media presence, working on documenting a user manual for the visualization portal and the new multi-study visualization feature, and converting analog metadata for 50,000 tissue samples from mice exposed to simulated Galactic Cosmic Radiation into the Laboratory Information Management System (SLIMS) as well as automating the data entry task. On August 10, 2023, the students finalized their summer programs with final presentations showcasing what they had accomplished.

Meet the Expert - Student Edition

The Open Science team hosted the fifth presentation in the "Meet the Expert" series showcasing various career paths ranging from academia to government and industry. This event was focused on summer students at NASA Ames as well as summer students working with the Open Science AWG community. 51 attendees participated in this virtual, hour-long event, where four panelists—Chris Sembroski, Amber Paul, Parag Vaishampayan, and Luis Zea—discussed their career paths followed by a discussion and a virtual networking social where the 27 summer students continued to connect with the experts as well as each other.

GeneLab for High Schools

GeneLab for High Schools (GL4HS) is a four week intensive training program for rising high school juniors and seniors sponsored by NASA’s Ames Research Center. GL4HS provides students an opportunity to immerse themselves in space life sciences with a specific focus on omics-based bioinformatics research, the science of collecting and analyzing complex biological data such as genetic codes, and computational biology. Applications open from January 10 - February 4, 2024.

2024 NASA HRP IWS

Registration is now open for the HRP Investigator's Workshop which will be held on February 13-16, 2024, in Galveston, Texas. Keep a look out for presentations by the Open Science team.

Upcoming AWG Symposium 2024

Pencil us in! The 2024 AWG Symposium will be held in the March/April time frame. So keep a look out for upcoming announcements regarding this event.

COSPAR 2024

Come check out OSDR's Sylvain Costes at COSPAR which will be held on July 13 - 21, 2024 in Korea. Sylvain will be the first speaker in the Interdisciplinary Lecture Session!

In 2023, a total of 75 transcriptomic, 15 genomic, and 3 proteomic/metabolomic, GeneLab datasets have been added to the Open Science Data Repository this year. 

To ensure omics data hosted on the GeneLab Data Repository are accessible to and interpretable by a broad scientific audience GeneLab collaborated with our AWG scientific community to develop and standardize consensus processing pipelines for each omics data type. Standardizing pipelines is necessary to minimize variation in data processing, which enables the integration of data from the diverse array of spaceflight and analog experiments hosted on GeneLab. View the latest 71 processed datasets.

Since January 2023, 33 ALSDA (pheno-physiological-behavioral-imaging) datasets have been released. A sampling of these datasets include: behavioral video from drosophila aboard the International Space Station; immunostaining microscopy of the retinal-blood barrier from RR9; muscle calcium uptake data from spectrofluorometry RR1 and RR9; echocardiogram-ultrasound data from mice exposed to low-dose oxygen ions and protons; and so much more. These first-to-be-released pheno-physio datasets enable multi-hierarchical analytics between the molecular genomic level to the tissue, organ, system, and whole organismal behavioral levels. Sincerest appreciation to the 100+ ALSDA AWG members who provided feedback on assay metadata and tabular/imaging data standards enabling scientific.

This brings the grand total to 470 datasets in the repository!

Stay tuned for more exciting news from Open Science in the Spring 2024 Newsletter!

The Open Science Team