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The latest in substance use disorders and pain management education for healthcare providers

March 2026

Greetings,


Welcome to the March edition of the MACS Monthly newsletter!


This month, we will recognize National Physicians Week (March 25–31) and National Doctors’ Day (March 30). These observances will provide the chance to celebrate the dedication, leadership and clinical expertise of our physician colleagues who work tirelessly to navigate the complexities of addiction medicine. At MACS, we see firsthand how their commitment to evidence-based care saves lives.


The impact of this commitment is backed by compelling data. Recent studies on integrated care models demonstrate that when a primary care physician incorporates addiction medicine into their practice, patients are twice as likely to remain actively engaged in their care and participate in digital health outreach. Furthermore, research indicates that providing office-based buprenorphine alongside harm reduction kits reduces drug-related mortality by 33%. By offering these life-saving medications and practical tools directly within the primary care setting, physicians can significantly lower the risk of fatal overdose while increasing a patient’s life expectancy by an average of 2.7 years.


In addition to celebrating our partners across the healthcare system, we want to extend a special thank you to our own MACS consultants. These physicians and experts serve as a collaborative resource, offering the clinical support and specialized guidance that help enhance the incredible work providers are already doing across Maryland. We are proud to see how their shared expertise helps strengthen the care delivered in our communities every day.


March is also Social Work Month, an opportunity to honor the pivotal role social workers play in treating individuals with substance use disorders (SUDs). These professionals provide a comprehensive continuum of services, ranging from initial screening and assessment to ongoing case management, individual and family counseling, crisis intervention and advocacy. Their work is essential in empowering individuals on their recovery journeys, supporting families affected by substance use and educating the next generation of social workers specializing in addiction treatment.


According to two studies conducted by the National Association of Social Workers, 71% to 87% of social workers have reported working with clients who have SUDs. These figures reinforce the need for robust resources to support these professionals, and MACS is grateful to all of Maryland's social workers providing essential care.


Healthcare providers can access support in caring for patients with SUDs and chronic pain by scheduling an individualized consultation or registering for an upcoming training with MACS. To learn more, call 1-855-337-MACS (6227), email macs@som.umaryland.edu or visit www.marylandmacs.org.


Explore this newsletter and the tools available on the MACS website for additional information about provider education and treatment resources.


– The MACS Team

MACS IN THE MEDIA

MACS Consultant Malik Burnett, MD MBA, MPH, was recently featured on the Tradeoffs podcast and took listeners inside REACH Health Services, where he serves as medical director.


Dr. Burnett has highlighted how REACH integrates addiction treatment with primary care to address patients’ complex needs like diabetes and heart failure alongside opioid use disorder (OUD).

NEW FACT SHEET

In 2023, a “3-day rule” exception to the Narcotic Addict Treatment Act of 1974 was enacted that allows practitioners to dispense up to a 3-day supply of methadone all at once to initiate treatment while a referral is coordinated.


This new fact sheet explores the clinical recommendations for the "3-day rule," which was established to help relieve acute withdrawal while arranging for long-term treatment. It provides guidance on patient and facility/provider eligibility, standardized protocols and specific dosing recommendations. The fact sheet also highlights essential safety monitoring and the importance of pairing medication with harm reduction measures like naloxone.

EDUCATION

Upcoming MACS Training Opportunities

MACS Webinar

Bridging the Gap: Practical Pain Management Across Primary and Specialty Care


Thursday, March 5 | 12:00 p.m. – 1:00 p.m.


Presented by MACS Consultant Sarah Merritt, MD

MACS Webinar

The Role of Telemedicine in Expanding Access to Medications for Opioid Use Disorder (MOUD) Care in Underserved Areas


Monday, April 20 | 12:00 p.m. – 1:00 p.m.


Presented by MACS Medical Director and Consultant Eric Weintraub, MD

Upcoming Trainings of Interest

Yale Program in Addiction Medicine

The Use of Medications for Opioid Use Disorder During Pregnancy


Tuesday, March 3 | 12:00 p.m. – 1:00 p.m.

Substance Abuse and Mental Health Services Administration

Addressing Veteran Substance Use: Promoting Recovery Through Collaboration and Compassion


Tuesday, March 3 | 2 p.m. – 3:30 p.m.

Central East Prevention Technology Transfer Center

Carry On: Preventing Veteran Suicide and Substance Misuse


Wednesday, March 11 | 1:00 p.m. – 2:30 p.m.

Grayken Center for Addiction Training & Technical Assistance

Alcohol Use Disorders 101


Tuesday, March 31 | 9:00 a.m. – 10:30 a.m.

MACS ECHO Sessions

Join our learning communities for continuous case-based discussions and didactic presentations linking expert specialist teams with healthcare providers and their practices. MACS ECHO sessions count toward the required 8-hours of SUD training for DEA license renewal or registration.

Opioid Treatment Program

Sustained Recovery: Extended-Release Buprenorphine to Treat OUD


Bethany DiPaula, PharmD


Wednesday, March 4

12:30 p.m. – 1:30 p.m.

Maternal Health

Birth Outcomes


Katrina Mark, MD, FACOG, FASAM


Tuesday, March 10

12:00 p.m. – 1:00 p.m.

Substance Use Care for the General Practitioner

Providing Addiction Care for the Unstably Housed Patient


Nicholaus Christian, MD


Wednesday, March 18

12:30 p.m. – 1:30 p.m.

Providing MOUD from a Trauma-Informed Perspective

Trauma and Adolescent Substance Use in Rural Communities: Clinical and Systems Implications for Integrated Care


Noah Triplett, PhD


Wednesday, March 25

12:00 p.m. – 1:00 p.m.

CONFERENCES & EVENTS

Society for Research on Nicotine and Tobacco Annual Meeting

Thursday, March 5

Hilton Baltimore Inner Harbor | Baltimore, Maryland

Presentation by MACS Director of Research and Evaluation Bethea Kleykamp, PhD

Tuerk Conference on Mental Health & Addiction Treatment

Wednesday, April 15

Baltimore Convention Center | Baltimore, Maryland

MACS Exhibit Table

Maryland Academy of Advanced Practice Clinicians Pharmacology Update 2026

Saturday, April 18

Doordan Institute Conference Center and Event Space | Annapolis, Maryland

MACS Exhibit Table

Maryland Chapter American College of Emergency Medicine 2026 Educational Conference & Annual Meeting

Thursday, April 30

SMC Campus Center | Baltimore, Maryland

MACS Exhibit Table

NEWS

Assessing the Initial Impact of X-Waiver Elimination on Buprenorphine Prescribing for Opioid Use Disorder


A recent study of over one million electronic health records shows that while the January 2023 X-waiver elimination successfully increased the odds of buprenorphine initiation for new OUD diagnoses by 14%, a significant treatment gap remains. Despite the removal of this regulatory barrier, only 19.6% of newly diagnosed patients received a prescription in the post-waiver period. These findings suggest that while policy changes are a step in the right direction, systemic barriers continue to hinder access to life-saving treatment, underscoring the need for further clinical integration and support.


Read more...

Peer Navigator Intervention and Opioid-Related Adverse Events for Emergency Department Patients



A randomized clinical trial involving 247 New York City emergency department patients found that peer navigator interventions did not significantly reduce opioid-related adverse events compared to standard site-directed care. Over a 12-month follow-up, the data showed no statistically significant differences in the rates of subsequent overdoses or substance-related ED visits between patients paired with "Wellness Advocates" and those who were not. While participants reported high satisfaction with the peer support, the study concludes that current peer-led models may need further refinement to move the needle on long-term clinical outcomes for high-risk populations.


Read more...

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study



A case-control, observational postmortem study has provided a look into the biological changes following decades of alcohol use. By analyzing post-mortem brain tissue from individuals with an average of 35 years of chronic alcohol consumption, the study revealed significant gene expression imbalances within the endocannabinoid system, which is a key modulator of reward, motivation, and impulse control. Notable findings include a 125% increase in CB1 receptor expression in the prefrontal cortex, which is linked to heightened relapse risk, and a 50% decrease in CB2 receptors, which suggests a stripping of the brain's neuroprotective and anti-inflammatory safeguards. These findings offer a neurobiological explanation for the impaired executive control and increased vulnerability to relapse seen in alcohol use disorder (AUD), underscoring the potential for new, targeted therapeutic strategies that address these specific molecular shifts.


Read more...

Travel Time to Methadone Treatment Via Personal Vehicle vs Public Transit


A cross-sectional study investigated how travel times to methadone treatment differ for those using personal vehicles versus public transit, specifically examining variations across demographic groups. The study estimated travel time for 2,702 census block groups in Connecticut to the nearest opioid treatment program (OTP). Median travel times from the areas with the highest per-capita overdose death rates were 8.2 minutes by personal vehicle compared to 37.6 minutes by public transit, with 34% lacking adequate access to the latter. These findings suggest that public transit access to methadone treatment is substantially limited, and areas characterized by high overdose death rates, low car ownership and long transit times should be prioritized for interventions designed to lower travel-based barriers to care."


Read more...

Holidays

MACS Phone Line Will Be Closed

May 25 – Memorial Day

March Observances

Social Work Month

Patient Safety Awareness Week

March 8 – March 14

National Physicians Week

March 25 – March 31

National Doctors' Day

March 30

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RESOURCES

ACF Expands Access to Medications for Opioid Use Disorder for At-Risk Families (U.S. Department of Health & Human Services)

Demand grows for doulas who can help moms with addiction (Stateline)

Integrated care is an opportunity and an imperative (American Psychological Association)

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