-37 patients completed the study, 50% of which were women. 1 patient was African American. Mean arterial pressure (MAP) was 132 mm Hg (120/ 80 mm Hg equals MAP of approximately 93 mm Hg). No other relevant characteristics were provided.
-Top Figure: There was no statistically significant increase in anti-hypertensive effect with escalating chlorthalidone doses.
-Bottom Figure: In a dose dependent fashion, serum potassium declined between 0.4-1.0 mEq/L and serum uric acid rose from 1.2-1.8 mEq/dL.
-Blood urea nitrogen and creatinine did not vary by dose. Episodes of acute kidney injury, changes in fasting blood glucose, and lipid parameters were not reported.
-Symptom questionnaires failed to reveal a difference in the frequency of gout, cramping, or fatigue.