ICTR March 2024 Newsletter                            

March 2024 NEWSLETTER

In This Issue


  • ICTR Pilot Projects Awarded
  • Support the CRTP and ICTR on Einstein Giving Day
  • Biostatistics Resources Available in the BERD House



Funding Opportunities:


  • New Learning Health System and Health Research Equity Training Award
  • PhD in Clinical Investigation Program Applications Due April 1st

ICTR Pilot Grant Awardees Named

We are excited to announce the awardees of the Einstein Montefiore Institute for Clinical and Translational Research (ICTR) Pilot Project Program pilot grants to support translational science projects:

Eric Bouhassira PhD

Production of Therapeutic Engineered Red Blood Cells


A major roadblock to the use of red blood cells as drug delivery vehicles has been the lack of a generalizable, scalable approach to load a variety of cargo into the cells without decreasing their lifespan. Dr. Bouhassira's project aims to address this by using a method to produce genetically modifies red blood cells in culture that his team has recently developed.

Tyler Grove PhD

Oxygen-Sensitive Proteins: Novel Targets for Biology and Medicine


Dr. Grove's project aims to demonstrate the feasibility of implementing robust infrastructure to identify hit compounds targeting O2-sensitive proteins for future development of inhibitors and tool compounds.

Lucas Sjulson PhD

Developing a Method to inactivate AAV-based gene therapies


Gene therapies based on adeno-associated viral vectors (AAVs) hold great promise for treating numerous diseases, but the fact that they are irreversible raises major safety concerns if adverse effects occur. Dr. Sjulson's project will work to develop and validate a method to permanently inactivate AAV-based gene therapies called Recombinase-Enabled Vector Inactivation and Reversal Technology (REVIRT).

Phyu Thwe PhD

Rapid Antimicrobial Susceptibility Testing of Slow-growing Microorganisms Using a Reporter Phage-based System


Dr. Thwe's project aims to use phages as a tool for antimicrobial susceptibility testing (AST) by using non tuberculous Myocobacteria (NTM) as a model and infecting NTM with reporter phages. Her team will optimize and design new phages for specific NTM species and hope to contribute to the development of new testing guidelines for phage-based AST testing applications in clinical laboratories in the future.

Projects supported by this program address a roadblock in translational science research. To learn more about the program, click here.

Learn About Translational Science Here

Support the ICTR and CRTP on Einstein Giving Day

The ICTR is working with the Office of Development for Einstein Giving Day 2024. Today, Pi Day (March 14th), we are taking part in a 24-hour fundraising challenge that brings together our community of alumni, parents, and friends to support the work that we do in the Clinical Research Training Program (CRTP) and the ICTR overall.


Donations will be used to: 

  • Expand data science initiatives
  • Provide pilot funding to advance translational science projects
  • Develop new courses about health equity, community engaged research, and implementation science


Please take a moment today to support the CRTP and ICTR by clicking here.

Biostatistics Resources Available at the BERD House

Look no further than the BERD House for all of your biostatistics resources needs! The BERD House is an online biostatistics resource managed by the Biostatistics, Epidemiology, and Research Design (BERD) core of the ICTR.

 

This resources includes guidelines for preparing a data set, tutorials on statistical testing and analysis, introductory R code, links to statistics software, statistics training opportunities, and other valuable resources.  

 

We invite you to explore the BERD House and take advantage of the wealth of information and tools available. For more methodoloigcal support, a biostatistics virtual walk-in clinic is available every Tuesday between 3-5pm at this Zoom link

Funding and Training Opportunities

Learning Health System and Health Research Equity Training Award LOI Due 3/29

Einstein and Montefiore, in partnership with Columbia University Center for Patient Safety Science invite faculty to apply for a new funding opportunity: The Learning Health System (LHS) and Health Equity Research and Training Award is a 2-year grant from the Agency for Healthcare Research and Quality (AHRQ) that supports faculty in conducting a systemwide research project focused on the intersection of equity and quality in healthcare. This unique opportunity provides 50% protected time, education, training, mentorship, tools, and resources to successfully complete a pilot research project and build a foundation of knowledge and skills to pursue future LHS research. Full application, by invitation only, will be due May 31st.


Interested applicants must submit a Letter of Intent to be considered for this training award by March 29th at 5pm.


Click here to learn more. Questions can be directed to wsouther@montefiore.org.

View EQUIP RFA

Applications to PhD in Clinical Investigation Program due April 1st

The PhD in Clinical Investigation (PCI) is offered as a concentration for predoctoral PhD students enrolled in Einstein’s graduate division and for M.D./Ph.D. students in Einstein’s Medical Scientist Training Program (MSTP). The PCI's program goal is to provide novel, innovative, and forward-looking pre-doctoral training for biomedical investigators seeking to develop careers in translational science, creating new knowledge to help promote human health and prevent or treat disease. 


Applications to the PCI are available and due April 1st. Qualified applicants can find more information about pursuing a PhD in Clinical Investigation through the Einstein Graduate Program in Biomedical Sciences, or the Medical Scientist Training Program/MSTP. For more information on how to apply, click here. Questions should be directed to nancy.marte@einsteinmed.edu.

View PCI Application

Research Community News

Cooperative Research Workshop: Reliance

The Office of Human Research Affairs (OHRA) will be hosting an in-person workshop on Reliance run by an expert in the field, Sehily Carlson (Assistant Director of Cooperative Research at OHRA). This initiative’s objective is to break down reliance in relation to the study review process. This workshop is targeted toward investigators, but open to anyone in the research community. This will take place on the Einstein campus on Wednesday, May 15th from 1-2pm. 


Registration Link: All About Reliance. If there are any questions, please contact Hope McCabe at hope.mccabe@einsteinmed.edu.


To sign up for the OHRA newsletter, click here.

2024-2025 Innovation Biodesign Training Program Call for Applications

The Montefiore Einstein Innovation Leadership Team is excited to announce a call for applications for the Innovation Biodesign Training Program’s 2024-2025 cycle. This one-year program is a unique experience to train the next generation of health technology innovators and encourages the development and validation of health technologies such as digital tools and devices. This initiative is only the sixth Innovation Biodesign Training Program in the United States and the first to focus on chronic conditions and health disparities.

 

Montefiore Einstein faculty and fellows from all departments are encouraged to apply to the Innovation Biodesign Training Program and residents can apply to the Innovation Training Pathway Program. Training will begin on July 1, 2024.

 

This program’s curriculum (3-4 hours required per week) includes: small group sessions, Innovation lab meetings, and a seminar series; a team-based health technology innovation project; mentoring from Montefiore Einstein faculty and external experts; and an end-of-program pitch presentation. All participants are required to have departmental sponsorship.

 

To indicate your interest in applying and to request the application packet, please e-mail Dr. Jariwala (sjariwal@montefiore.org). The application deadline is April 15, 2024.

Biodesign Training Program
Resident Innovation Training Pathway

Early-Stage Investigator Physician Diversity In Clinical Trials Award Program

The Robert A. Winn Diversity in Clinical Trials Career Development Award is is two-year program designed to support the career development of early-stage investigator physicians preparing them to become independent clinical trial investigators engaged in advancing health equity through their research and mentoring. Applications are open until May 13th 2024. To learn more and apply, click here.

Cite the CTSA

The Block Institute for Clinical and Translational Research (ICTR) is part of the Clinical and Translational Science Award (CTSA) program funded by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). Cite NIH funding in manuscripts, press releases, and other communication forums. All publications, press releases, or other documents that result from the utilization of any Einstein Montefiore CTSA resource are required to credit the CTSA grant and comply with NIH Public Access Policy (submission to PubMed Central). To learn more, click here.

Weekly NIH Funding Opportunities and Notices
Non-government, Corporate and Foundation Funding Opportunities
Harold and Muriel Block Institute for Clinical and Translational Research
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