Joseph C. Maroon: A neurosurgeon explains the dangers of marijuana
Post Gazette
June 27, 2024
A few facts: Marijuana comes from the cannabis plant, which produces over 50 different chemicals called cannabinoids. Tetrahydrocannabinol (THC) is the potent cannabinoid that gives marijuana its psychedelic effects. Whether smoked, vaped, or eaten, the THC passes into the brain and affects the connections — or synapses — between neurons. THC makes users feel calmer and less stressed, and it may increase their appetite.
An avalanche of research now confirms that marijuana has serious short-term risks and severe and potentially permanent long-term risks, especially for young users. The 2½-pound human brain with 86 to 100 billion neurons is not fully developed until the mid-20s, which means it remains a major work in progress.
We now know that marijuana actually changes both the chemical makeup and the anatomical structure of the brain during critical developmental stages. A recent study established baseline MRI scans of nearly 800 adolescents (13 to 17) who used marijuana. A follow-up MRI five years later showed actual atrophy — or shrinkage — of the prefrontal cortex, the region of the brain that regulates our thoughts, actions, and emotions.
The tragic irony is that while the dopamine released by marijuana can provide short-term relief from anxiety and depression in young people, its long-term effects can actually make their propensity for mental issues far worse. Why? The brain becomes reliant on the “feel good” dopamine provided by the THC and in turn produces even less dopamine itself.
Advocates for marijuana use have clung to the claim that it’s not addictive. Yet the evidence that the brain is altered by THC, that the brain becomes reliant on THC, and that users experience withdrawal symptoms when they try to stop using it all point to an addiction. And calling this addiction “marijuana use disorder” only minimizes its dangers.
In addition to increasing anxiety and depression, addiction to THC has other deleterious effects. It increases suicidal thoughts and eating disorders. It raises the probability of dropping out of school and having impaired social relationships.
The way it fundamentally alters the brain can also lead to psychotic breaks and to disorders such as schizophrenia and paranoia, especially if there are past personal or family issues with mental health.
Read More Here
|