The P2 Weekly
APRIL 17, 2020 | ISSUE 1
Formulations We Need
WHO and FDA Recommended Hand Sanitizer 
According to the recent relaxed regulations* around compounding hand sanitizer to meet the surge in need caused by COVID 19, there are 2 basic formulations that are permitted for manufacture and distribution by non-FDA approved facilities so long as they register with the FDA and comply strictly with the guidelines. From the guidance:

This hand sanitizer is compounded according to the following formula consistent with World Health Organization (WHO) recommendations:

a)    Alcohol (ethanol) (formulated to 80%, volume/volume (v/v)) in an aqueous solution; or Isopropyl Alcohol (formulated to 75%, v/v) in an aqueous solution.
b)    Glycerin (glycerol) (1.45% v/v).
c)    Hydrogen peroxide (0.125% v/v)
d)    Sterile distilled water or boiled cold water.

The primary virtues of these formulations are their simplicity and their efficacy. They offer next to no moisturization, save a small amount of glycerol to prevent excessive drying-out of the skin. There is explicit guidance that prohibits the use of additional gelling agent, fragrance, or moisturizer. So there it is. The bare-bones, straight to the point Bonus Formulation.

P2 Science registered with the FDA and elected to go with the 80% ethanol formulation. We now are getting as much as we can out to the community, including to critical childcare facilities.
*Policy for Temporary Compounding of Certain Alcohol-Based Hand Sanitizer Products During the Public Health Emergency Immediately in Effect Guidance for Industry : March 2020, updated April 15,