MiTeGen Newsletter

Cryogenic X-ray Crystallographic Studies of Biomacromolecules at Turkish Light Source "Turkish DeLight"

Cryogenic X-ray Crystallographic Studies of Biomacromolecules

Image Source: Atalay, et al. (2022). Cryogenic X-ray Crystallographic Studies of Biomacromolecules at Turkish Light Source "Turkish DeLight".  bioRxiv 2022.09.03.506456; doi:

In an article at BioRxiv, Necati Atalay et al. describes research involving high-resolution structural analysis of biomacromolecules from single crystals at the new X-ray diffraction facility at the University of Health Sciences, Istanbul. "The methods and practice described in the article can be applied to any biological sample for structural studies. Therefore, this article will be a valuable practical guide from sample preparation to data analysis."

Several of our MiTeGen tools were used in the research including our loops, pins and basesUni-pucks, shipping cane, and CX-100 dryshipper.

Read at the article at BioRxiv

New Cryo-EM Grid Clipping Station

The new Nanosoft Cryo-EM Grid Clipping Station provides unmatched ease of use and efficiency for the clipping of cryo-EM grids for Thermo Fisher autoloader-based microscopes.

This new clipping design makes the workflow easier, and a well-designed lid balances ease of use and protection. Furthermore, the Clipping Station is compatible with both NanoSoft and Thermo Fisher clipping tools.

Learn More About the Grid Clipping Station

Webinar - Simplifying Cryo-EM with the Latest Innovative Tools

Are you interested in learning about innovative solutions that can help you overcome the difficulties of sample preparation in cryo-EM? Then register for ThermoFisher Scientific's November 9th edition of Ask the Experts.

Panelists include Dr. Claudia López and Nancy Meyer of the NIH Pacific Northwest Cryo-EM Center as well as MiTeGen's CEO Ben Apker. They will discuss the tools and technologies now available as well as tips and tricks to help you get optimal results from highly difficult proteins.

ThermoFisher Scientific Ask the Experts
Register Today

Have You Tried Our Loops Yet?

If you are using another brand of loops for your crystallography research, we encourage you to give our loops a try.  Our loops are trusted by researchers and have been mentioned in over 2000 research publications.

To start with, visit our loop selection guide.  Then, visit our loop department to choose the loop appropriate for your research. 

We also offer a loop sampler kit that can be customized to your needs by contacting us

Need help in selecting the correct loop for your research? Then please contact us and request a consultation on choosing the appropriate loop for your research.

Contact Us Today
Upcoming Events
At MiTeGen, we sponsor numerous events, conferences, workshops and symposiums throughout the year. These events include fields such as structural biology, crystallography, cryo-EM, beamline research and more. We believe in supporting researchers and our industry. Listed below are two upcoming events you might find interesting.
Annual Buffalo-Hamilton-Toronto (BHT) Crystallography-CryoEM Symposium

The Buffalo-Hamilton-Toronto Crystallography-CryoEM Symposium is November 4th.  Features discussions and the chance to learn about innovative techniques in X-ray crystallography and cryoEM.  We are sponsoring and exhibiting at the symposium.

Learn More
SoCal Cryo-EM Symposium

The 7th Annual Southern California CryoEM Symposium is December 5th at UCLA. Features scientific talks, networking session, poster sessions and vendors booths. We are sponsoring and exhibiting at the symposium.

Learn More
Looking For More Events, Workshops and Conferences

If you are looking for more events visit our events page. It lists conferences, workshops, symposiums, user meetings and more.

Topics include structural biology, material science, crystallography, cryo-EM, beamline research and more.

Visit Our Events Page
Industry Resources and News

Here is a small selection of industry resources and news for your browsing.

  • The ACA (The Structural Science Society) is hosting a series of spotlight sessions on early career members of the ACA. The "goal is to provide an opportunity for early career members to share knowledge, experiences, and ideas." - Learn More
  • IUCrData has launched a new section named Raw Data Letters. This "new section will publish short descriptions of crystallographic raw data sets from X-ray, neutron or electron diffraction experiments, in the biological, chemical, materials science or physics fields, and provide a persistent link to the location of the raw data." - Learn More
  • The Plunge, a new podcast examining the past, present and future of cryo-EM as well as career developments and experiences of experts in the field of cryo-EM. - Learn More
  • Practical Fragments, a blog where Fragment-based Drug Design Practitioners discuss non-confidential issues regarding fragments. - Learn More
  • The Cambridge Crystallographic Data Centre's Structure Solution webpage offers material by "expert crystallographers and educations to help others teach the wonders of crystallography" - Learn More
  • Wellcome has commissioned a survey "to identify new key areas that have the potential to transform the field of bioimaging. The review will cover bioimaging methodologies, tools and technology development across the scales of life – from atoms all the way to humans – that are applicable to discovery research." - Learn More 
  • Canadian Light Source has just released its 2021 Research Report which highlights "new beamline capabilities, science highlights, industry research, education collaborations, and publications." - Learn More
  • HZB has just released its 2021 Highlight Report which "presents compact information on important developments at HZB and a selection of the scientific results published in renowned journals." - Learn More
  • The Summer 2022 Shutdown Recap at Advanced Light Source is now available. - Learn More
  • ThermoFisher Scientific has created a cryo-EM return on investment (ROI) calculator to help determine "how soon cryo-EM can begin providing you with a tangible return on your investment." - Learn More
  • Read about EMSLs (Environmental Molecular Sciences Laboratory) resources for cryo-EM imaging and their proposal mechanisms. - Learn More 
  • New tool at COSMIC2 called Isonet. It is a "generative deep learning tool, for cryoET, that attempts to remove the missing wedge from tomograms." - Learn More
  • On October 16th the Australian Synchrotron is having an open house to the public through which they can learn how synchrotron light can be used for a range of scientific outcomes. - Learn More
  • Article at MAX IV, Creating Tastier Vegan Cheese Using Synchrotron X-rays. - Learn More
  • The proceedings from the CCP4 Study Weekend 2020 on Model Building, Validation and Representation in MX and CryoEM can now be viewed as a virtual issue. - Learn More
  • Advanced Light Source has a call for 2021 and 2022 publications resulting from work done in whole, or in part, at the ALS. - Learn More 
Industry Jobs
MiTeGen Jobs Board
Searching for a new job? Interested in knowing what positions labs and facilities are offering? Then visit our jobs board on which we list recent industry job offerings.

And remember, if you have an industry relevant job, we are happy to list it on our jobs board.
Visit Our Jobs Board
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