Mitegen October Newsletter
Crystallography Cryo-EM and AlphaFold Working Together
Image Source: Luca Jovine (2022). Crystallography, cryo-EM and AlphaFold shed light on key human antibacterial proteins March 11, 2022, 
In an article at, Karolinska Institutet explains how crystallography, cryo-EM and AlphaFold were used to understand, "two similar proteins that prevent bacterial infection in the urinary tract and the gastrointestinal system."

Further in the article it is explained that AlphaFold was used to "make sense of the GP2 X-ray information and fit low resolution cryo-EM maps of UMOD." It is interesting to see how AlphaFold is being used to support traditional methods such as crystallography and cryo-EM.
New Product - Reverse Action Autogrid Tweezers
We now offer the reverse action autogrid tweezers. These tweezers provide grid security by holding the autogrid reliably in the natural "closed" state. The tweezers still provide notched tips, cradling the autogrid & centering it for placement into a cassette
Popular - XP Screens Intelligent Crystal Screens with TEW
One of the more popular products we offer are the XP Screens which promote protein crystallization even for most challenging targets and improve diffraction quality of protein crystals.

The XP Screens are TEW-optimized JBScreen Basics: 96 of the most prominent crystallization conditions complemented with TEW as “glue” for protein molecules. Read about why you should use TEW in Protein Crystallography.
Support the USNC/Cr
The USNC/Cr is looking for support in paying its annual IUCr dues. The dues allow U.S. scientists to serve in leadership roles within the IUCr Executive Committee, the IUCr General Assembly, the scientific commissions of the IUCr, and the editorial boards of IUCr Journals.

Contributions can be made through the National Academy of the Sciences where you can choose the “Other” option and enter the name of this project as “IUCr dues”. Please also inform Joe Ferrara (USNC/Cr Vice Chair) via email,, so he can verify the receipt of your contribution by the USNC/Cr. Joe can also provide instructions on other contribution mechanisms, such as ACH electronic transfers or paper checks. MiTeGen is a proud supporter of the USNC/Cr.
Upcoming Events
At MiTeGen, we sponsor numerous events, conferences, workshops and symposiums throughout the year. These events include fields such as structural biology, crystallography, cryo-EM, beamline research and more. We believe in supporting researchers and our industry. Listed below are two upcoming events you might find interesting.
The Michigan University Cryo-EM summer workshop is June 5th to the 9th at the University of Michigan. The focus of this four-day workshop class is to introduce participants to common image processing packages used to analyze cryo-EM data. We are sponsoring this workshop.
The 2022 inaugural symposium of the Dubochet Center for Imaging is June 8th to the 10th at The University of Geneva & The University of Lausanne / EPFL . Features electron microscopy scientific talks, tour of the DCI Lausanne facility, and more. We are sponsoring this workshop.
Looking For More Events, Workshops and Conferences
If you are looking for more events visit our events page. It lists conferences, workshops, symposiums, user meetings and more.

Topics include structural biology, material science, crystallography, cryo-EM, beamline research and more.
Feedback from Event Organizers
We sponsor many events throughout the year. Listed below is a summary for BioXFEL.

"BioXFEL, a National Science Foundation Science and Technology Center, hosted its 9th annual international conference virtually in February 2022. Scientists and up-and-coming researchers from around the world joined to remember Dr. John Spence, discuss cutting-edge results, and learn new ways to create more diverse and inclusive environments. We were pleased to partner with MiTeGen on this event and information about the 2023 conference will be posted online at"
Industry Resources and News
Here is a small selection of industry resources and news for your browsing.

  • is celebrating 75 years of science with synchrotron light with the #My1stLight campaign. The campaign is inviting all those connected with light source science to share their #My1stLight memories so that they can celebrate the amazing journey that the field has been on during the past 75 years - Learn more
  • ThermoFisher Scientific is offering a talk concerning career paths and new opportunities in cryo-EM April 20th - Learn more
  • New introductory online course to Synchrotron and XFEL Radiation – Techniques and Applications is being offered by École Polytechnique Fédérale de Lausanne (EPFL) - Learn more
  • EMBO is offering a course about theoretical and practical foundations of advanced cryo-electron microscopy - Learn more
  • The Pacific Northwest Cryo-EM Center is offering a Microscope Operation course that provides hands-on sample preparation, microscope operation, daily alignments, user interface, SerialEM and EPU training for automated data collection - Learn more
  • Microscopy Australia offers an interactive training on cryo-EM for those who want to learn about microscopy - Learn more
  • LINXS & MAX IV Laboratory are offering a masterclass in data collection and structure determination in macromolecular crystallography June 6th to the 10th - Learn more
  • Scientists who seek to learn more about cryo-electron microscopy and anticipate using the technique in future research are invited to apply for the inaugural National Cryo-EM Facility Cryo-EM Training Program - Learn more
  • Learn about crystallography in France via an article at IUCr newsletter. Includes a look at facilities, recent activities and teaching in France - Learn more
  • Every Friday Euro-Bioimaging hosts The Virtual Hub a virtual meeting that showcases the success stories and expertise, exciting science, travel grants, new technologies and more for the nodes at Euro-Bioimaging - Learn more
  • Beamline for Schools is an international physics competition for high school students that is organized by CERN - 2 teams of high-school students have a chance to come to CERN & conduct an original physics experiment - Learn more
  • The European XFEL has protein crystal screening proposals and expressions of interest in long-term proposals - Learn More
  • Read the summary recap of the 30th Annual Meeting of the German Society of Crystallography - Learn more
  • Just for fun, Dr Sam Horrell ran the first ever Synchrotron Mug Madness competition on Twitter where light sources competed to determine who had the best mug - Learn more
Industry Jobs
Searching for a new job? Interested in knowing what positions labs and facilities are offering? Then visit our jobs board on which we list recent industry job offerings.

And remember, if you have an industry relevant job, we are happy to list it on our jobs board.
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