The year of 2020 will be remembered for the novel coronavirus global pandemic, a historic national election, the political uprising after the death of George Floyd in the US, and the challenges we all individually faced in the wake of these events. At the Mesulam Center, faculty, staff, and clinicians have navigated these challenges to continue operations, research endeavors, and provide clinical care for those with dementia. We have put together a timeline of 2020 to reflect on the ways we have adapted.