As we approach the end of 2020 and look forward to a new year, I think we can all agree that this year has been unlike any other. In January, we started hearing reports from China about a new respiratory disease and saw it rapidly impact Wuhan, and then escalate to a lock-down in China, before escalating to impact international travel. As I flew from Australia to Hawaii in early February, travel from China to many parts of the world was closing, and when I returned home 2 weeks later the situation was moving fast. We have all now seen national borders close and international travel severely disrupted, and this ultimately impacted our ability to travel to Toronto for the ISDE’s 2020 Congress. I am also aware that I haven’t left my own Australian State since February, and even though Australia has been less affected than Europe and the Americas, it has still been through “lock-downs” and we are yet to return to a situation that resembles what we previously took for granted. Read the full Message from the President.
The Controversies in Gastroesophageal Reflux Disease virtual presentation was held on December 16, 2020. Moderated by Jan Tack, University of Leuven (The Netherlands) and Kerry Dunbar, University of Texas Southwestern Medical Center (USA), this 90-minute presentation is available in three segments on the ISDE Youtube Chanel.
Esophageal adenocarcinoma (EAC) has had the fastest increasing incidence of any solid tumor in the United States in the last 30 years. Long-standing gastroesophageal reflux disease is a well-established risk factor with strong associations with obesity, alcohol and tobacco. However, there are likely additional contributing factors. Viruses such as human papillomavirus, ebstein-barr virus and herpes simplex virus have been implicated in the pathogenesis of esophageal cancer. This review will discuss the known literature linking viruses to esophageal adenocarcinoma and consider future relationships such as identifying prognostic and predictive molecular biomarkers to guide therapies. Read the full Viruses and esophageal cancer article for free.
A less invasive endoscopic therapy has been used as a routine treatment for superficial esophageal squamous cell carcinoma (SESCC). However, lymph node metastasis (LNM) in SESCC limits the effectiveness of this medical procedure. This meta-analysis aimed to screen the risk factors for LNM in SESCC in Asia to provide evidence for clinicians in selecting treatment. We searched the main reference databases for research involving patients who received esophagectomy (open or minimally invasive) with lymph node dissection for SESCC. Meta-analysis was performed using RevMan 5.3 software. Twenty studies including 3983 patients were obtained in this analysis. Read the full Prediction of lymph note metastasis article for free.
Minimally invasive esophagectomy is a complex operation with a long learning curve and the robotic platform has allowed increased utilization of a minimally invasive approach. Find out more in the latest Diseases of the Esophagus Supplement and don't forget to tell us what you think on Facebook or Twitter.
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This second edition of the well-accepted first edition edited by Professor Ando contains up-to-date information on squamous esophageal cancer from a variety of perspectives. This book is recommended as a comprehensive guide to diagnosis and management.