Volume 02 | May 3, 2021

The Digital Collaborative has launched its own website! The site will act as a virtual home to connect all member entities and showcase UCSF’s digital work. The website will increase the visibility and awareness of the exciting work happening within Digital Collaborative member groups.
The Bakar Institute just launched the new version of PatientExploreR - a powerful, user-friendly, research-oriented data exploration tool. PatientExploreR provides an ability to search UCSF de-identified clinical data and explore characteristics of groups of patients with an easy-to-use cohort selection interface. The patient cohorts generated by the PatientExploreR search can be visualized and filtered using the tool's interactive plotting features. Users can view and download data for individual patients, or export detailed data for a cohort to further analyze with other tools. >>More Info
Scholarship Program for EHR Data Extraction Services
The demand for electronic health record (EHR) data for clinical and health services research continues to increase at UCSF. In addition to increasing our staffing to support this demand, CTSI will also be launching new processes, for data access including a new scholarship program to cover the first 8 hours of EHR data extraction for researchers that need it (e.g., faculty or trainee with limited funding, pilot research project prior to a funded grant). This means that Academic Research Systems (ARS) will no longer automatically provide 8 free hours of data extraction per fiscal year per PI. CTSI will continue to provide a first free hour of consultation for all projects. 

The scholarship fund application is brief, and will be available if needed through our usual data extraction request process. >>More Info

Julia Adler-Milstein, PhD, and colleagues provide some of the first national-level data characterizing hospital organizational strategies surrounding EHR adoption and use, and identify which strategies are associated with adoption of advanced EHR functions. 
CTSI’s Research Methods Core Renewal
The recently renewed CTSI has a major focus on digital science in the service of clinical research. Christine Cassel (Senior Advisor for Strategy and Policy in the Department of Medicine) will be working with Barbara Koenig and Ida Sims on Core E, oriented to provide ethics and regulatory understanding and tools to investigators working with patient data in digital science research. Building on the University of California Report, A Justice Based Framework for Health Data Governance, the Core will oversee the development of a new framework for electronic health data use in research and seek innovation in achieving public understanding and support for data use. 
The UC San Francisco Department of Radiology and Biomedical Imaging noted a significant milestone for both the department and the UCSF Center for Intelligent Imaging (ci2): full deployment of an artificial intelligence (AI)-enabled portable x-ray device into our clinical environment.“This is the first example (with many to come) of AI algorithms developed by UCSF Radiology being used in production at UCSF for clinical care,” says John Mongan, MD, PhD, associate professor and associate chair for translational informatics at UCSF Radiology and director of translational informatics at the ci2. >>Read More
Investigators at the UCSF Center for Intelligent Imaging (Ci2) examined the potential of Radiopaedia – a wiki-based international collaborative radiology educational web resource containing reference articles, radiology images and patient cases – to serve as a general radiology corpus to produce radiology specific word embeddings that could be used to enhance performance on an NLP task on radiological text. >>Read More
In early 2021, the Bakar Institute released a new version of the Machine-Redacted Clinical Notes set, now available to UCSF researchers via a streamlined access process. IRB approval is still required to access; however, the certification of this data asset is well underway, which will enable simplified access without IRB approval, with UMLS standard clinical concepts coming this month! Machine-redacted notes can be explored via a user-friendly tool, EMERSE, created at the University of Michigan and implemented for UCSF by the CTSI Research Technology team. >>Read More
On April 30, 2021, UCSF S.O.L.V.E. Health Tech hosted a virtual summit to build agreement across stakeholder groups around the barriers to digital health equity and discuss action-oriented solutions to overcome them. Speakers included the National Coordinator for Health IT, the lead for health equity in the Biden administration, and the clinical lead for Google Health. A recording of the summit will soon be available on the U.C.S.F. SOLVE Health Tech website.
Adler-Milstein J, Raphael K, O’Malley TA, Cross DA. Information Sharing Practices Between US Hospitals and Skilled Nursing Facilities to Support Care Transitions. JAMA Netw Open. 2021;4(1):e2033980. doi:10.1001/jamanetworkopen.2020.33980
Butte AJ. Trials and Tribulations—11 Reasons Why We Need to Promote Clinical Trials Data Sharing. JAMA Netw Open. 2021;4(1):e2035043.
doi:10.1001/jamanetworkopen.2020.35043 >>Full Article
Hsu WY, Rowles W, Anguera JA, Zhao C, Anderson A, Alexander A, Sacco S, Henry R, Gazzaley A, Bove R. Application of an Adaptive, Digital, Game-Based Approach for Cognitive Assessment in Multiple Sclerosis: Observational Study. J Med Internet Res. 2021 Jan 20;23(1):e24356. doi: 10.2196/24356. >>Full Article
Block VJ, Gopal A, Rowles W, Yueh C, Gelfand JM, Bove R. CoachMS, an Innovative Closed-Loop, Interdisciplinary Platform to Monitor and Proactively Treat MS Symptoms: A Pilot Study. Mult Scler J Exp Transl Clin. 2021 Feb 2;7(1):2055217321988937. doi: 10.1177/2055217321988937. >>Full Article
Bardach NS, Lam R, Jasik CB. Assessment of Automated Clinical Trial Recruitment and Enrollment Using Patient-Facing Technology. BMJ Health Care Inform. 2021;28(1):e100076. doi:10.1136/bmjhci-2019-100076 >>Full Article
Odisho A, Singer J, Perez A, Leard L, Shah R, Golden J, Kleinhenz M, Kolaitis N, Maheshwari J, Liu A, Trinh B, Kukreja J, Greenland J, Calabrese D, Hays S. Implementation of a Chatbot Mobile Health Intervention with Home Spirometry to Monitor Lung Transplant Recipients Remotely. The Journal of Heart and Lung Transplantation, 2021. 40(4), S146. doi:10.1016/j.healun.2021.01.446 >>Full Article
Health Informatics Grand Rounds
Health Informatics Grand Rounds is hosted by Russ Cucina, the UCSF Health Chief Health Information Officer, and are attended by an array of physicians, nurses, researchers, trainees and other professionals passionate about health informatics. Contact Dr. Raman Khanna to be added to the calendar invite.

4th Thursdays | 3:30pm – 5:00pm
BIDS-BCHSI Research Xchange Forum
Title: "Digital Health Platform for Corneal Opacities and Cataracts Management"
Speaker: Saeed Seyyedi, PhD, Innovate for Health Fellow

May 4, 12:30 - 1:30 pm
MORE INFO (registration required)

Title: "Bayesian Logistic Regression for Online Recalibration and Revision of Risk Prediction Models with Safety Guarantees"
Speaker: Jean Feng, PhD, Assistant Professor
UCSF Department of Epidemiology & Biostatistics

Title: “Evolutionary Forces Shape the Genetic Architecture of Complex Traits”
Speaker: Ryan Hernandez, PhD, Associate Professor
UCSF Department of Bioengineering and Therapeutic Sciences
Meeting ID: 931 2647 5111 ZOOM LINK
Passcode: 619405