July 2016
Dear Colleagues,

The July edition of Discoveries brings you new research on drug delivery for brain injuries, a therapeutic target for limiting heart attack damage, and other exciting advances. We also have updates on what postdocs are doing and recent high-profile events highlighting the Institute’s prime position in cancer research.

We welcome your feedback!

New technology could deliver drugs to brain injuries

A study led by Erkki Ruoslahti, M.D., Ph.D., describes a technology that could lead to new therapeutics that reduce the damage caused by traumatic brain injuries. The discovery, published in Nature Communications, provides a means of homing drugs or nanoparticles to injured areas of the brain.

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Select Media Coverage: Medical News Today, Tech Times, The Science Explorer,
San Diego Union-Tribune

Science News
Scientific breakthrough may limit damage caused by heart attacks

An advance from the laboratory of Mark Mercola, Ph.D., could lead to new drugs that minimize the damage caused by heart attacks. The research, published in Nature Communications, reveals a key control point in the formation of new blood vessels in the heart.

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Select Media Coverage: FierceBiotech, KPBS

Dietary restriction increases lifespan through effects on the gut

Dietary restriction, or limited food intake without malnutrition, has beneficial effects on longevity. A new study from the research group of Malene Hansen, Ph.D., published in PLoS Genetics, shows that dietary restriction leads to these advantages in part by enhancing autophagy in the intestine. 

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Muscle heat may hold key to promoting weight loss

New research from the laboratory of Muthu Periasamy, Ph.D., could pave the way for treatments that help obese patients burn calories without exercising. An investigation published in the Journal of Biological Chemistry shows that muscle can be stimulated to burn calories as heat.

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Unveiling a tumor survival strategy points to a new drug target

Searching for new ways to keep cancer cells from surviving without oxygen, scientists in the group of Garth Powis, D.Phil., found a double whammy. Publishing in Cancer Research, they identify a target that would both starve the tumor of energy and block responses that would bring it more oxygen.    

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Postdoc Jessica Rusert shares science with the community

At an event organized by the Reuben H. Fleet Science Center, Jessica Rusert, Ph.D., a postdoc in the lab of Robert Wechsler-Reya, Ph.D., recently discussed precision medicine with interested members of the public.
Krissa Smith, former postdoc, now research program manager at Susan G. Komen

Krissa Smith, Ph.D., a postdoc in the laboratory of William Stallcup, Ph.D., from early 2010 to late 2011, now manages the scientific review of grant applications for the Susan G. Komen Foundation.
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Institute News
Celebrating 40 years

On July 7, staff in La Jolla gathered for a commemorative photo in honor of the Institute’s anniversary. The day was named Sanford Burnham Prebys Medical Discovery Institute Day by Mayor Kevin Faulconer.

Welcome to our newest and recently renewed President's Circle Members!
• Alex's Lemonade Stand Foundation for Childhood Cancer
• Gary Chessum
• Bess and Arthur Collias
• Carol and Thomas Dillon
• Joan and Archie Freitas
• Christine Infante
• Jean and Gary Shekhter
President's Circle
Please Donate
Cancer Moonshot satellite summit held at Sanford Burnham Prebys

Our Institute was one of 10 sites selected to co-host an official summit as part of the kick-off for the Vice President's Cancer Moonshot. The event brought together cancer researchers, survivors, and leaders of biotech and pharmaceutical companies to discuss ways to accelerate progress.

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Cancer metabolism symposium highlights hot area in cancer research

Research on cancer metabolism promises to find ways to starve tumors of the fuels and building blocks they need to grow. This strategy is attracting a lot of excitement, leading to the packed house at SBP’s fourth symposium on the topic.

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