November 7, 2025

Edition 106

Editor’s Note: Welcome to Discovery Digest, a biweekly newsletter from Children’s Hospital of Philadelphia Research Institute. Each edition highlights the most recent news in pediatric science featured on the Research Institute's Cornerstone blog. From publications, faculty awards, new grants, and more, keep reading Discovery Digest to find out how our talented research teams are solving the most challenging problems in children’s health.

 
 


Take a peek inside the CHOP-Penn Proteomics Core, a unique, state-of-the-art research resource empowering investigators to study "the molecules that carry out the work of life." Learn more in our latest Tour the Cores Q&A with Technical Director Lynn Spruce.


 
 
 

CHOP and Penn Vet researchers found in a preclinical study that mitochondrial dysfunction in the blood-brain barrier may underlie neuropsychiatric symptoms in some patients with 22q11.2 deletion syndrome. “… our results could have broad therapeutic implications,” said senior author Stewart Anderson, MD, of the Department of Child and Adolescent Psychiatry and Behavioral Services.

 
 
 

A large trial will examine two strategies to increase the implementation of supraglottic airways when a baby needs help breathing immediately after birth. “This trial is a great opportunity to leverage our expertise here at CHOP to advocate for and collaborate with centers that may not have access to the same resources,” said lead Principal Investigator Dr. Elizabeth Foglia of the Division of Neonatology.

 
 
 

The FY26 Faculty Spotlight Series features Elizabeth Sanseau, MD, a faculty member in the Division of Emergency Medicine, who focuses on ensuring that hospitals and clinics serving American Indian and Alaska Native children are prepared for emergencies. “In the long run, my goal is simple: that every child — no matter where they live — receives the best care possible in an emergency,” Dr. Sanseau said.

 
 

Press

Releases


View the latest CHOP press releases to learn more about cutting-edge clinical practices and advances in medical research.

 

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