New study shows significant relationship between changes in vitamin D levels and changes in lipid levels, with decreasing vitamin D linked to worsening lipid profile
Does Increasing Vitamin D Levels Also Raise Cholesterol Levels?

Several questions about vitamin D and cholesterol levels have been asked of us in the past, such as “Does increasing my vitamin D level or supplementing with vitamin D raise cholesterol levels,” or “Do vitamin D levels change with cholesterol levels?” While there have been a small handful of studies and trials on the subject, we have not had any specific answers for those questions up until this point. A paper recently published helps to shed light on the topic, and is reviewed below.
Real-World Data Reveals Relationship between Year to Year Changes in Vitamin D and Lipid Levels
In an effort to further clarify the relationship between vitamin D and lipid levels, Li et al. analyzed data from a real-world setting, using laboratory measurements obtained from an annual employee health program. Their goal was to see if there was a consistent, significant relationship between year-to-year increases or decreases in vitamin D levels and changes in serum lipid levels. They split the data into cohorts according to year:

  • Cohort 1 contained measurements from 5580 individuals for the years 2017 to 2018
  • Cohort 2 contained measurements from 6057 individuals for the years 2018 to 2019
  • Cohort 3 contained measurements from 7249 individuals for the years 2019-2020

Each cohort was split into two different groups – those whose vitamin D level increased by 10 ng/ml (25 nmol/L) or more from one year to the next, and those whose vitamin D level decreased by 10 ng/ml or more. Changes in total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) were also evaluated for each of the two groups within each cohort.
Increasing Vitamin D Levels Linked to Decreased Cholesterol Measures
For each year to year comparison, the authors found a significant decrease in TC, LDL-C, and TG levels among those whose vitamin D level had increased by 10 ng/ml or more. They also found a significant increase in TC, LDL-C, and TG levels among those whose vitamin D level had decreased by 10 ng/ml or more.
As can be seen in the chart above, where orange bars indicate decreasing vitamin D levels and green bars indicate increasing vitamin D levels, TC, LDL-C, and TG levels increased (worsened) when the vitamin D level went down by at least 10 ng/ml (25 nmol/L) over the year, and decreased (improved) when vitamin D level went up by at least 10 ng/ml over the year. For those whose vitamin D levels increased by 10 ng/ml (25 nmol/L) or more, compared to those whose levels decreased, there was an approximate reduction in

  • Total Cholesterol by 10-12 mg/dL
  • LDL-C by 7-8 mg/dL
  • And Triglycerides by 21-28 mg/dL

These changes remained significant even after adjusting for age, sex, race, education, BMI, blood pressure, smoking status, geographical location, vitamin D level at baseline, and lipid level at baseline. While changes in HDL-C were observed, these changes were slight and not statistically significant for all groups.

In summary, this study showed that
“individuals who had year-over-year increases in vitamin D levels tended to have corresponding decreases in levels of TC, LDL-C, and TG. Conversely, individuals who had year-over-year decreases in vitamin D levels tended to have increases in TC, LDL-C, and TG levels.”
These findings support previous research showing that reductions in vitamin D levels are associated with worsening lipid profiles, and with this, the authors suggest that vitamin D supplementation may be of benefit for individuals with dyslipidemia.
Vitamin D is an Easily Modifiable Factor to Help Improve Disease Outcomes – Make Sure You Are Getting Enough
Having and maintaining healthy vitamin D levels, as well as omega-3s and other nutrients, can help improve your health now and for your future. Choose which to measure, including essential minerals such as selenium, magnesium, and zinc, and more, by creating your custom home test kit today.  Take steps to improve the status of each of these measurements to benefit your overall health. You can also track your own intakes, symptoms and results to see what works best for YOU.

Enroll and test your levels today, learn what steps to take to improve your status of vitamin D (see below) and other nutrients and blood markers (such as TSH), and take action! By enrolling in the GrassrootsHealth projects, you are not only contributing valuable information to everyone, you are also gaining knowledge about how you could improve your own health through measuring and tracking your nutrient status, and educating yourself on how to improve it.
What does the Research Say about Vitamin D & COVID-19?
Be sure to educate yourself on the benefits and importance of vitamin D for immune health, and take steps to ensure you and your loved ones are getting enough.

You can review all of the COVID-19 and immune health information shared by GrassrootsHealth on this page.
What Does it Take YOU to Get Your D to 40 ng/ml (100 nmol/L)?
Did you know that everyone responds differently to vitamin D supplement amounts - by up to 6 times!? Your health could be greatly affected by making sure you have a vitamin D level of at least 40 ng/ml (100 nmol/L). Help us help you.
Don't get stuck with low vitamin D levels - learn more about what might affect your level and response to supplementation, and the steps to take through each season to keep levels in your target range.
Children with Diabetes Research Foundation
The mission of CWDRF is to fund research leading to the cure and prevention of Type 1 diabetes. For over 20 years, they have been the venture capitalists of diabetes research, getting new, clinically relevant, innovative research off the ground.

CWDRF is currently funding the D*action Type 1 Diabetes Prevention project with GrassrootsHealth.
Highly Absorbed Magnesium
Dr. Carolyn Dean is a medical doctor, naturopath, and author of over 35 books including best seller The Magnesium Miracle. With 40 years of experience, she offers proprietary, unique formulations that give every individual at any stage of wellness or illness the necessary building blocks for sustained health, vitality and well-being.

Participate in our special Magnesium*PLUS Focus project offered by RnAReSet.
The Helen Knoll Foundation
The Helen Knoll Foundation (HKF) mission is to prevent breast cancer by empowering young women through risk awareness education, advocacy and access to age appropriate screenings. HKF with GrassrootsHealth is launching the Know YOUR Number campaign to help Stop Breast Cancer Before it Starts by working with local groups to provide vitamin D blood spot testing and project enrollment events.
Have a beautiful and HEALTHY day.
Text-to-give: Text Daction to 44321
Carole Baggerly
Director, GrassrootsHealth
A Public Health Promotion & Research Organization Moving Research Into Practice NOW!
315 S. Coast Hwy 101, Suite U-87
Encinitas, CA 92024
(760) 579-8141