Unleashing the Potential of Drugs through Empowered Drug Evaluation

Drug evaluation results have a significant impact on decision-making in biopharmaceutical development. By employing various methodologies and experimental models, drug evaluation helps identify promising drug candidates, optimize potential drugs, and prioritize the most viable candidates for further development. The integration of comprehensive drug evaluation during early drug discovery and preclinical phases accelerates the drug development process, increases the chances of successful clinical outcomes, and ultimately contributes to improving patient healthcare.

ACROBiosystems offers innovative solutions, Pre-formed Fibrils (PFFs), researchers can enhance their understanding of drug behavior, optimize drug candidates, and make informed decisions during early drug discovery and preclinical evaluation.

Pre-formed Fibrils (PFFs) for Disease Modeling

Pre-formed Fibrils (PFFs) are important in modeling neurodegenerative diseases. They are intermediate structures formed during protein misfolding and aggregation. PFFs-based disease models offer improved drug evaluation by recapitulating disease pathology, providing reproducible experimental conditions, targeting disease-specific pathways, assessing drug effects on aggregation kinetics and cellular toxicity, and facilitating high-throughput screening.