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Your monthly news & updates
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ECTS Announcements and Events
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Do not miss the ECTS exciting activities and events. Renew your 2019 ECTS membership
here
- ECTS 2019 pre-congress and congress register with late/onsite fee. See scientific programme here. Register here.
- Recordings of our last 2 webinars on Paget's disease of bone by Federica Scotto di Carlo and Stuart Ralston are now available, check them out if you missed them
- 9th International Conference on Children's Bone Health (ICCBH) - register with standard fee, deadline 24 May 2019. Register here
- ECTS Webinar: Interaction between bone cells and glucose metabolism by Nicolas Bonnet, 30 May 2019 4 pm CEST - Register here
- AMGEN competitive grant program in bone research to improve outcomes of osteoporotic patients. Deadline: 28 June 2019 (11:59 pm PT) Details here
- Bisphosphonates' 50th anniversary meeting, Sheffield, UK 15-17 July 2019 - More information
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ECTS PhD Training Course 2019, 8-10 September 2019, Bologna, Italy -
More information
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ECTS-Mellanby-SVGO Training Course on Diagnostic Tests for Osteoporosis "Bone Turnover Markers",
12 September 2019, Basel, Switzerland -
More information
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Budapest: history and science, a unique opportunity
By István Takács &
Anna Teti
Traces of the first settlements in the area of the city of Budapest today date back to the Stone Age, but many nations alternated throughout history in longer or shorter periods. The first golden age was under the Roman Empire, when the roman town of Aquincum -today part of Budapest - was the capital of Pannonia province from 106 AD until the end of the 4th century. Under the leadership of the famous Attila, Huns advanced in the Pannonian Plain in the 5th century. Later in 896, conquering Hungarian tribes led by Árpád crossed the Carpathians and settled in the area. The coronation of the first king Stephen the 1st in 1000 marks the foundation of the Hungarian state.
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The ECTS PhD Training Course, a privileged meeting for PhD students.
7-10 September 2019, Bologna, Italy
By Claudine Blin
The ECTS PhD training course is specifically dedicated
to students at all stages of their PhD and has been hailed as one of the most innovative and successful courses in the bone field.
Besides promoting general knowledge of bone research, the ECTS PhD training course is a unique opportunity for PhD students to present and discuss their project with specialists and to start building their own scientific network. It also offers complementary training in transferable skills.
This year, the program will cover topics such as ER stress and bone, bone and muscle crosstalk, bone biomechanics and vascular physiology. It will also focus on bone diseases (bone metastasis, osteoporosis, osteopetrosis, Paget disease) from basic research to clinical trials. Speed mentoring sessions will be organized by members of the ECTS academy. And two workshops will be proposed on intellectual property and plagiarism and how to prepare for a presentation.
Whatever the stage of your PhD, don't miss the next ECTS PhD training course!
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3rd ECTS Charity event:
Help us fundraise for the Hungarian Federation of People with Rare and Congenital Diseases
by Carmen Huesa and Petar Milovanovic
At this year's annual meeting, ECTS and ECTS Academy are organizing the ECTS Charity Football (five-a-side) tournament. We invite all interested delegates, members, corporate supporters and friends to join us and help us fundraise for the Hungarian Federation of People with Rare and Congenital Diseases. In addition to being for a good cause, this is also supposed to be fun and a good opportunity to bring together members, corporate supporters and friends. Last year, thanks to your support, we raised more than 1,400€ for Camurati-Engelmann's Disease. So, get your friends and colleagues together to form your team to play in the tournament.
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Yellow, green and red osteoclasts show us their developmental origin and functional maintenance
By Teun J. de Vries.
When asking newcomers to the field of the biology of the multinucleated, bone degrading osteoclasts on how such a multinucleated cell arises and dies, they quickly come up with great hypotheses. For instance, fusion one by one could be a possibility, or fusion of two existing osteoclasts. They could die all of a sudden cell death or not, splitting up or shedding nuclei, fission could occur of already formed osteoclasts. In vitro, this may all be true, but now a recent article in Nature (linked below) has refined our understanding of this myeloid lineage-derived cells in vivo. Using smart mouse osteopetrosis models, Jacome-Galarza et al. were able to show that embryonic erythro-myeloid progenitor (EMP) lineage of resident macrophages give rise to the initial osteoclasts needed for tooth eruption, proper formation of bone marrow cavity and the morphologically normal development of skulls and long bones. With classical parabiosis experiments, forcing a shared blood circulation between two mice, but now in contrast to the 1980's with fluorescent tagged cell models, they were able to show that hematopoietic stem cells (HSC) derived cells contribute to the maintenance of osteoclast by a slow-pace, one-by-one fusion of precursor cells. One cell per two weeks contributed to an existing syncytium, the average size of osteoclast, with 5-7 nuclei per osteoclast, slightly increased over time. Fused contributor nuclei persisted for a long time. Together, it meant that it took up to six months to replace all nuclei from an existing osteoclast. Osteoclasts are once again revisited, now as long-lived, dynamic cells that welcome new nuclei and likely get rid of non-functioning nuclei every fortnight.
© 2018/2019 Springer Nature Publishing AG
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ECTS Announcements and Events
-
Do not miss the ECTS exciting activities and events. Renew your 2019 ECTS membership
here
- ECTS 2019 pre-congress and congress register with late/onsite fee. See scientific programme here. Register here.
- Recordings of our last 2 webinars on Paget's disease of bone by Federica Scotto di Carlo and Stuart Ralston are now available, check them out if you missed them
- 9th International Conference on Children's Bone Health (ICCBH) - register with standard fee, deadline 24 May 2019. Register here
- ECTS Webinar: Interaction between bone cells and glucose metabolism by Nicolas Bonnet, 30 May 2019 4 pm CEST - Register here
- AMGEN competitive grant program in bone research to improve outcomes of osteoporotic patients. Deadline: 28 June 2019 (11:59 pm PT) Details here
- Bisphosphonates' 50th anniversary meeting, Sheffield, UK 15-17 July 2019 - More information
-
ECTS PhD Training Course 2019, 8-10 September 2019, Bologna, Italy -
More information
-
ECTS-Mellanby-SVGO Training Course on Diagnostic Tests for Osteoporosis "Bone Turnover Markers",
12 September 2019, Basel, Switzerland -
More information
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ECTS is thankful to its Corporate Members and other companies that have supported ECTS activities through unrestricted educational grants. These sponsors have in no way contributed to or influenced the content.
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Editor in chief: Teun De Vries (Amsterdam, The Netherlands)
Co-editors: Carmen Huesa (Edinburgh, UK), Cristiana Cipriani (Rome, Italy)
Marco Ponzetti (L'Aquila, Italy)
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