Minneapolis Heart Institute Foundation

Endovascular & Vascular Research

Q2 2025

Research Highlight

Based on the most recent enrollment update from May, we are close to being among the top 5 enrolling sites in the US for ADVANCE.

The trial recently celebrated 3 great milestones:

Site activation phase is complete, with 63 sites active globally.
300th global enrollment completed in Spain.
100th enrollment in the United States at Minneapolis Heart Institute Foundation

Study Spotlight: ADVANCE

Description

The ADVANCE study is a post-market randomized trial comparing the Medtronic Endurant stent graft system vs Gore Excluder/Conformable AAA Endoprosthesis system. It seeks to use the comparison to further understand aneurysm sac regression as a key indicator of long-term EVAR (Endovascular Aneurysm Repair).

Contact

Sara.Behmanesh@allina.com

Principal Investigator

Dr. Jeffery Jim

Enrolling Clinical Studies

Study

Study Summary

PI and Enrolling Sites

ASSETS

Minneapolis Heart Institute Foundation

Hybrid IDE study for surgeon modified fenestrated AAA graft

Dr. Jesse Manunga

ANW

HERCULES

Rijnstate Hospital

Post-market study of endosuture aneurysm repair with Heli-FX EndoAnchor system vs. standard endovascular aneurysm repair in AAA

Dr. Jeffrey Jim

ANW & United

ADVANCE

Medtronic

Post-market randomized trial comparing the Medtronic Endurant stent graft system vs Gore Excluder/Conformable AAA Endoprosthesis system

Dr. Jeffrey Jim

ANW & United

CGUARDIANS II

InspireMD

IDE study to evaluate the CGuard Prime carotid stent system for use in TCAR procedures

Dr. Jeffrey Jim

ANW & United

TRG 23-02AA Gore Registry

W.L.Gore & Associates

Assessment of long term outcomes for the Gore Excluder Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis in real world AAA interventions

Dr. Elliot Stephenson

ANW & United

Pipeline Studies

Serranator POINT FORCE Registry

Cagent Vascular

Post-Market ClINical Follow-up STudy oF the SerranatOR PTA Serration Balloon CathEter

Dr. Mohammad Khasawneh

ANW & United

SKYWARD

Shockwave

Trans-carotid IDE study of a new carotid purpose-built IVL device to treat high-risk patients (prior to stenting) that may not be good candidates for CEA

Dr. Jeffrey Jim

ANW & United

Abbreviations: ANW = Abbott Northwestern Hospital; AAA = Abdominal Aortic Aneurysm; EVAR = Endovascular Aortic Repair; ESAR = EndoSuture Aneurysm Repair; TCAR = Transcarotid Artery Revascularization; IDE = Investigation Device Exemption; IVL = Intra-Vascular Lithotripsy; CEA = Carotid Endarterectomy; PTA = Percutaneous Transluminal Angioplasty

For more information, please contact John Meriwether at john.meriwether@allina.com

Interested in clinical trials from our other areas of cardiovascular research? Visit mplsheart.org/archive for any recent emails you may have missed.