The selection of a target antigen is crucial when developing an ADC strategy. After identifying the antigen, the initial step in an ADC development project involves extensive screening to identify suitable monoclonal antibodies for specific target recognition. We offer products for quick, high-throughput antibody screening suitable for ADC applications.

Recommend products: ADC target proteins; Over-expressed cell lines; inhibitor screening kits

The anticancer activity of ADCs also involves ADCC, ADCP, and CDC effects. The Fab segment of antibodies in certain ADCs binds to the antigen epitope on virus-infected cells or tumor cells, while the Fc segment binds to Fc receptors on the surface of killer cells, mediating direct killing effects.

Recommend products: Report cell lines for ADCC/ADCP functional assay

The antibody, a crucial component of an ADC, ensures target specificity and serves as the carrier for the cytotoxic payload. Diverse conjugation chemistries allow for payload attachment at different sites on the antibody. Our site-specific conjugation kit allows for precise and controlled conjugations, resulting in a narrower drug-to-antibody ratio (DAR).

Recommend products: AGLink ADC site-specific conjugation kit for conjugated GDP-Fuc-vc-PAB-MMAE with your antibody.