Gelucire® 48/16: Polyoxyl-32 stearate

• Water-soluble
• MP: 48°C
• HLB: 12

Gelucire® 44/14: Polyoxyl-32 laurate

• Water-dispersible
• MP: 45°C
• HLB: 11

Gelucire® 59/14: Polyoxyl-32 laurate + PEG 6000

• Water-dispersible
• MP: 59°C
• HLB: 14

Excellent solubility and bioavailability enhancer

• Solubilised / dispersed in water or milled into powder
• Added in binding liquid or as part of dry mix in wet granulation
• Alternative to polysorbates and sodium lauryl sulfate

Comparison with market reference

• Fenofibrate tablets had nice appearance and good hardness
• Good in vitro dissolution similarity
• Good reproducibility in scale-up study
• Stable release for normal and accelerated conditions

Download our CRS poster and contact us for the case study now!

Need further assistance?

Gattefossé can help you select the right lipid

excipients for the intended dosage form and the desired delivery profile