FORTE Fridays

December 2025

www.nrgoncology.org

This special broadcast will be released monthly on Fridays to highlight materials posted on CTSU, along with any updates and upcoming events related to FORTE.

Happy Holidays from FORTE!

Update: Site Network Establishment Funding

Having awarded over 20 Site Network Establishment Funding awards in the years since NRG-CC005 activation, NRG has halted the application process for the one-time start-up application to enhance recruitment. Contact forte@nrgoncology.org with any questions on FORTE funding.

New Enrollment Record!

Thanks to the efforts of the national clinical research teams supporting enrollment to NRG-CC005, the FORTE team is excited to report that the trial set a new record of 143 participants in October 2025.

We’re in the final sprint to accrue 3800 participants by the end of the year, 40% of total enrollment!

FORTE Site Call – March 12, 2026 – Protocol Compliance

Join the quarterly FORTE site calls to hear updates on NRG-CC005 and discuss challenges and solutions with other research professionals working to enroll patients to this clinical trial. Registration for these virtual sessions are in these monthly FORTE Fridays broadcasts.

To kick off Colorectal Cancer Awareness Month, the next FORTE Site Call will be on March 12, 2026. FORTE Protocol Chair, Dr. Robert Schoen, will discuss protocol compliance.

NRG Patient Reported Outcomes (PRO) Compliance Officer, Marcie Ritter, presented on compliance at the last FORTE Site Call. Watch the recording on the FORTE | Research Professionals playlist.

NRG 2026 Winter Meeting

Join NRG Oncology in San Francisco for the NRG 2026 Winter Meeting. The meeting will be held in-person, January 22-24, 2026, with select virtual sessions being held January 12-19, 2026. Registration is now open: https://www.nrgoncology.org/Winter2026Mtg/Register. Register before January 2, 2026, to avoid late fees.

Attend the NCORP Townhall at 10:00 am on Friday, January 23, to hear an update on NRG-CC005 trial progress.

UPDATE: FORTE Patient Trifold Brochures

The FORTE Patient Trifold Brochure is a resource available to NRG-CC005 sites to contact patients about this trial. Patient materials have been updated to reflect the change in eligibility guidelines that allows patients between 45 and 70 years to enroll in FORTE. This brochure can be mailed with introductory information about FORTE to patients to educate them before a phone call. They can also be placed in clinics as reading material, pinned to bulletin boards, included with colonoscopy prep instructions and more.

Request physical copies from the NRG Oncology office in Pittsburgh by emailing forte@nrgoncology.org. Please include the number of brochures and a mailing address for your site in this email.

FORTE Office Hours

Do you have questions on FORTE trial conduct? Join FORTE Office Hours on Microsoft Teams on the second Thursday of every month to ask your questions. Whether they’re related to screening, enrollment, sample collection, or follow-up, no question is off the table!

Next FORTE Office Hours:

December 11

2:00 pm ET

Microsoft Teams

Join the meeting now

Meeting ID: 295 778 582 392

Passcode: bW3Xo25C

Find both CIRB-approved and protocol-related documents on CTSU under NRG-CC005.

FORTE Resource Portal

Bookmark this website, that organizes materials found on CTSU: https://www.nrgoncology.org/Clinical-Trials/NRG-CC005/FORTE-Resource-Portal. You will use the same login information as for CTSU to access this page. Once you gain access, the “FORTE Materials for Research Professionals” section contains many materials to assist you with accruing participants. This website also has contact information for questions you may have while working on NRG-CC005.

Clinical research professionals can sign up for NRG Weekly Broadcasts to receive FORTE Fridays updates directly to your inbox. Click here to sign up.

Contact communications@nrgoncology.org for assistance with signing up for NRG broadcasts.

Questions from Site Research Staff

If research staff have questions about a patient's eligibility or study logistics for the NRG-CC005/FORTE Study, contact the Clinical Coordinating Department (CCD) at: FORTE@nrgoncology.org or 1-800-477-7227.

Follow FORTE on Social Media!