FEATURE ARTICLE:
How Stress and Loneliness Can Increase Susceptibility to COVID-19
By Jeff Fitlow / Rice University

What do stress, loneliness and lack of sleep have in common? They are all factors that can weaken your immune system and make you more susceptible to COVID-19, according to Rice University’s Christopher Fagundes, an associate professor in the department of psychological sciences who studies the link between mental and immune health.

“In my field, we have conducted a lot of work to look at what predicts who gets colds and different forms of respiratory illnesses, and who is more susceptible to getting sick,” Fagundes said. “We’ve found that stress, loneliness and lack of sleep are three factors that can seriously compromise aspects of the immune system that make people more susceptible to viruses if exposed. Also, stress, loneliness and disrupted sleep promote other aspects of the immune system responsible for the production of pro-inflammatory cytokines to over-respond. Elevated pro-inflammatory cytokine production can generate sustained upper respiratory infection symptoms.”And while this previous research has centered on different cold and upper respiratory viruses, he said “there is no doubt” that these effects would be the same for COVID-19