The executive committee catalyzes research and unites dozens of talented scientists from departments across campus. Nelson Freimer, MD is the Director of the DGC. A psychiatrist and geneticist, he has devoted his career to understanding the causation and course of mood disorders, including both major depression and bipolar disorder. Michelle Craske, PhD is a distinguished professor, departments of Psychology and Psychiatry and Biobehavioral Sciences, and Director of the UCLA Anxiety and Depression Research Center, who studies risk factors for depression and anxiety and new, more effective treatment models. She leads the Innovative Treatment Network component of the DGC. Jonathan Flint, MD is a psychiatrist who has led the largest and first successful study of the genetic basis of depression. He moved from Oxford University to UCLA to lead the 100K Study component of the DGC. Larry Zipursky, PhD distinguished professor in Biological Chemistry and Howard Hughes Medical Institute Investigator, leads the discovery neuroscience component of the DGC.