Experiential Learning for Emerging and Novel Technologies (ExLENT)

Through this new initiative, the Directorate for Education and Human Resources (EHR) and the newly established Directorate for Technology, Innovation and Partnerships (TIP) seek to support experiential learning opportunities for individuals from diverse professional and educational backgrounds that will increase access to, and interest in, career pathways in emerging technology fields (e.g., advanced manufacturing, advanced wireless, artificial intelligence, biotechnology, quantum information science, semiconductors, and microelectronics).

Deadline: 3/2/2023

Point-of-Care Technologies Research Network: Technology Research and Development Centers (TRDC) (U54 Clinical Trial Optional)

The purpose of this funding opportunity announcement is to solicit Technology Research and Development Center (TRDC) applications for the Point-of-Care Technologies Research Network (POCTRN). The POCTRN catalyzes innovation in diagnostic technologies through a network model that enhances complementary strengths and builds multidisciplinary partnerships across scientific/technological, clinical, regulatory, and commercialization domains. Each TRDC will accelerate the development, validation, and deployment of point-of-care, home-based and other innovative testing technologies in a specific area of health research. The POCTRN TRDCs will merge scientific and technological capabilities and expertise with clinical need and market demand to address unmet testing, monitoring, and treatment demands. This opportunity is open to all applicants, including the existing POCTRN grantees and new applicants.

AIDS Deadline: 1/7/2023

Toward ElucidAting MechanismS of HIV Pathogenesis within the Mission of the NIDDK (Pathogenesis TEAMS) (R01 Clinical Trial Optional)

This Funding Opportunity Announcement (FOA) seeks to support multidisciplinary research teams with complementary expertise in HIV and pathobiology, pathophysiology, and/or metabolism in organs, tissues, and/or biological systems of specific interest to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). These teams will comprehensively interrogate fundamental biological mechanisms underlying HIV-associated comorbidities, co-infections, and complications relevant to the mission of the NIDDK and advance progress toward preventing or alleviating them.

AIDS Deadline: 3/15/2023

Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed)

The purpose of this funding opportunity announcement (FOA) is to support preclinical HIV/AIDS research using NHP models performed by Early Stage Investigators (ESIs) who are within 10 years of their terminal degree or completion of their residency training but who have at least two years of postdoctoral experience. The goal of this support is to help advance HIV/AIDS researchers using NHP models in preclinical research by providing a degree of independence for these ESIs to develop new research directions and to position these researchers to be competitive for new research funding (e.g., R01). Proposed projects must use NHPs as preclinical models for HIV/AIDS research.

AIDS Deadline: 1/7/2023

Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications that will advance translational research to better understand the emergence, trajectory, and outcomes of schizophrenia and related psychotic disorders in mid- to late-life, and to identify targets for future development of prevention and treatment interventions.

Deadline: 2/22/2023

BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative and Integrative Models of Behavior at the Organismal Level (R34 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) seeks applications with limited scope proposing a set of planning activities that will lay the groundwork for a scientific project aimed at integrating complementary theories and methods to 1) develop, validate, and apply cutting-edge tools and methods for minimally invasive, multi-dimensional, high-resolution measurement of behavior at the level of the organism, with synchronous capture of changes in the organism’s social or physical environment; and/or 2) develop computational methods that allow for integration of multidimensional behavioral and environmental data representing multiple timescales into a conceptual and/or computational model of behavior as a complex dynamic system, designed with the capacity to integrate synchronously recorded neural data and/or inform existing models of neurobehavioral function, such as those developed with the support of the NIH BRAIN Initiative.

Deadline: 2/14/2023

Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and/or clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae.

Deadline: 2/5/2023

Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54 Clinical Trial Optional)

This funding opportunity seeks to support the Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) Program. The CPACHE Program develops and maintains comprehensive, long-term, and mutually beneficial partnerships between institutions serving underserved health disparity populations and underrepresented students (ISUPSs) and NCI-designated Cancer Centers (CCs). The program aims to achieve a stronger national cancer program and address challenges in cancer and cancer disparities research, education, and outreach, as well as cancer's impact on underserved populations.

Deadline: 1/6/2023

Climate Program Office (CPO), Earth System Science and Modeling Research in support of the Disaster

Climate variability and change present society with significant economic, health, safety, and security challenges. As part of the National Oceanic and Atmospheric Administration (NOAA) climate portfolio within the Office of Oceanic and Atmospheric Research (OAR), Climate Program Office (CPO), the Earth System Science and Modeling (ESSM) Division programs address climate challenges by managing competitive research programs that support high-priority science initiatives. CPO/ESSM Programs advance our understanding of the Earth’s climate system and foster the application and use of this knowledge to improve the resilience of our Nation and its partners. Through this announcement, CPO/ESSM is seeking applications for two individual competitions in FY23.

Deadline: 1/26/2023

Evaluating Innovative and Sustainable Treatment Options for Biosolids

The disposition landscape for biosolids has been relatively stable in recent years, with more than half of biosolids land applied and the rest largely either incinerated or landfilled. However, outside pressures and issues (e.g., PFAS, emerging constituents of concern, regulations) may reduce the availability of these existing options, prompting a need for innovative treatment, disposal, and beneficial use alternatives for biosolids. Today, utilities are increasingly seeking options outside the norm to treat their biosolids, especially technologies that can reduce costs, provide high-quality treatment, and potentially generate value

Deadline: 12/13/2022

Cultural and Community Resilience

Resilience is the ability to prepare for, recover from, and adapt to the impacts of our changing climate and world. The CCR program supports community-based efforts to mitigate the impacts of climate change and the COVID-19 pandemic by safeguarding cultural resources and fostering cultural resilience through the identification, documentation, and/or collection of cultural heritage and community experience.  

Deadline: 1/12/2023

Racial Equity in STEM Education (EHR Racial Equity)

This solicitation aligns with the National Science Foundation (NSF) and the Directorate for Education and Human Resources (EHR) long-standing investments in the development of a diverse and well-prepared public and workforce, which was recently reinforced in the NSF Vision: "A nation that leads the world in science and engineering research and innovation, to the benefit of all, without barriers to participation," p. 9, NSF 2022-2026 Strategic Plan (https://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf22068). The NSF Strategic Plan focuses on ensuring that U.S. research is an inclusive enterprise that benefits from the talent of all sectors of American society – a research enterprise that incorporates the rich demographic and geographic diversity of the nation. The strategic plan recognizes that the more people who engage in science, technology, engineering, and mathematics (STEM) research and the more diverse their backgrounds, the richer the range of questions asked. The result is a greater breadth of discovery and more creative solutions to societal challenges.

Deadline: 1/17/2023