Federal Appeals Court Clears Way for Generic Entresto

Products Now Available

On Tuesday, the U.S. Federal Circuit Court of Appeals denied Novartis’s attempt to prevent a generic manufacturer from marketing and selling its generic version of Novartis’s Entresto product. Although the appeal will continue, generic versions are now available pending the appeal. 

Manage Inventory Ahead of Generic Launch

We encourage members to actively manage the inventory of the brand product and return any excess stock they do not anticipate needing. A high conversion rate to the generic is expected, although reimbursement metrics remain uncertain at this time.

This is now a multi-source generic launch, with Alembic positioned as a preferred PRxO supplier, offering more than 60% savings compared to the brand. Alembic product is expected to be auto-shipped, and price protection is anticipated to play a role in this transition.

Alembic Options

10294529-SACUBITRIL-VALSARTAN 97-103 MG TAB 180

10294545-SACUBITRIL-VALSARTAN 24-26 MG TAB 180

10294547-SACUBITRIL-VALSARTAN 49-51 MG TAB 180

10294528-SACUBITRIL-VALSARTAN 97-103 MG TAB 60

10294621-SACUBITRIL-VALSARTAN 49-51 MG TAB 60

10294622-SACUBITRIL-VALSARTAN 24-26 MG TAB 60

Big Changes for Medicare Part D Program

Be Educated, Be Prepared!

The Medicare Part D program will change significantly in 2026. These changes will be seen in the net price you pay for the most popular and expensive Part D brand drugs and how much you get paid for these drugs. Be prepared for a cash flow impact and take steps before January in order to ensure you can receive all of the payments you are entitled to. We have prepared the basics of what you need to know about the Medicare Drug Price Negotiation Program.

American Pharmacies will match contributions to the Tennessee Pharmacists Association’s (TPA) Pharmacy Practice Preservation Fund (PPPF). TPA is alerting pharmacists to a critical legal challenge that could reshape pharmacy practice in Tennessee and beyond. A recent federal ruling in McKee Foods vs. BFP, Inc. (Thrifty Med Plus Pharmacy) struck down portions of Tennessee’s PBM reform laws, citing ERISA preemption. The state has appealed, and TPA—alongside NCPA—is filing an amicus brief in support of that appeal.

This case could set a national precedent for state PBM regulation, making your support more important than ever.



To help advance these vital legal efforts, TPA is encouraging contributions to the Pharmacy Practice Preservation Fund (PPPF)—a dedicated fund created to support legal and policy advocacy on behalf of pharmacy. Both individuals and organizations are invited to contribute.

Donate now to support this urgent legal effort. Stand with us in defense of your profession.

On July 10, the PBM Reform Act was introduced in the U.S. House of Representatives. This bill is a bipartisan effort to stop abusive PBM practices in Medicaid and Medicare Part D.

As a pharmacist, APEX 2024 speaker Rep. Carter (Ga.) knows firsthand how PBMs hurt patients and local pharmacies—and he’s joining with bipartisan group of Congresspersons to take action including APEX 2025 speaker Rep. Diana Harshbarter (Tenn.) and APEX 2023 speaker Rep. Vicente Gonzalez (Tex.). Other sponsors include: Debbie Dingell (Mi.), Greg Murphy (N.C.), Deborah Ross (N.C.), Jodey Arrington (Tex.), Rick Allen (Ga.), Raja Krishnamoorthi (Il.), John Rose (Ten.), Derek Tran (Ca.), and Nicole Malliotakis (N.Y.).

Click the button below to learn more about this bill.

This leading refill adherence program is designed and statistically proven to drive maximum profitability and operational efficiency. 

It leverages key RxCompass tools, including the Refills on Time (Advanced) and Refills on Time Using Pickup Date reports, to help pharmacies stay ahead.

You can access these valuable reports in RxCompass under:

Transactional Reports > Dispensing. 

GUIDED GROWTH

🚀 SURPASSES $11M Milestone 🚀

American Pharmacies’ Guided Growth program is breaking records—now a powerful $11 million initiative thanks to the outstanding efforts of participating APRx members. With over 150,000 total fills captured through concise but impactful patient outreach, pharmacies are seeing real results.

This high-impact program helps members drive Rx volume, boost Star Ratings, increase profit, and address nutrient depletion, all while strengthening patient relationships. Even more impressive, calls are frequently leading to additional prescriptions from other household members—further increasing the value of each interaction.

Guided Growth is proving to be a game-changer. Are you in?

APRx VP of Pharmacy Analytics & Clinical Services Jeff Jacobs, CPhT presents Dave Olsen (right) with the 2025 RxCompass User of the Year Award at APEX. Olsen also earned this honor in 2024.

Join the New APRx Exchange Today—Get $50 Instantly!



We are very excited to announce the launch of the APRx Exchange program!

We have established a new partnership with InStockRx, a trusted pharmacy marketplace, to launch this new initiative.

Learn more about this new partner program

Download the flyer

What this means for you: As a member of APRx you are already enrolled in the APRx Exchange. Registering means that other pharmacies, including other APRx members, can send you cash offers for your surplus inventory! Plus, the APRx Exchange is a great place to source branded and generic meds at a discount compared to NADAC.

When you register, you get access both to the APRx Exchange and to the broader InStockRx marketplace where you can securely trade with every store connected to InStockRx.

How the APRX + InStockRx partner program works

It’s Back: Shop the Annual Buying Event on Cencora Marketplace

Get ready to stock up, save big, and explore new front-end products during the Annual Buying Event on Marketplace — exclusively for Cencora customers.



For the entire month of July, over 9,000 Marketplace items will be discounted, and all Annual Buying Event promotions include 90-day payment terms to help maximize your cash flow.

Extended Offer Just for American Pharmacies Members

• Spend $200+ on Marketplace by July 31st and receive a $50 statement credit* — just enter code APEX50 in the PO field at checkout.
• This credit is in addition to the Annual Buying Event discounts!
• View the full details and instructions here

What’s on Sale?

Social Media: Member, Staff & Industry News in the Spotlight

APRx team exhibits at the Texas Pharmacy Association Conference and Expo 

Caremark hit with $95M judgement for overbilling Medicare Part D

APRx member Cypress Wellness Pharmacy in Fort Myers, FL — named Storytelling Champion at ThoughtSpot 2025!

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