March 8, 2019
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In The News
Developing Wound-Healing Tissue Scaffolds from Protein in Blood
Researchers have found a plasma protein in blood that could help develop a new method for making wound-healing tissue scaffolds. The scaffold can be attached or detached from a surface for tissue studies or direct applications to the body. This research could be pertinent to the future use in wound healing and tissue engineering. Professor Dorothea Brüggemann, lead author from the University of Bremen, says, "The protein we used is called fibrinogen. It is an extracellular glycoprotein found in blood plasma and plays a major role in wound healing by assembling into a fibrous network to form a provisional extracellular matrix (ECM) that helps with wound closure."

Electroceutical Bandages Can Help Heal Wounds Faster 
Bandages infused with electricity can help heal wounds faster than typical bandages or antibiotics--but for years, researchers have not really understood why. A recent study by a team at The Ohio State University is offering new clues about the science behind those bandages, and researchers say the findings could help lead to better wound treatment. The bandages belong to a class of therapies called electroceuticals, which are devices that use electrical impulses to treat medical issues such as wounds. The study, published online recently in the journal Scientific Reports by a research team at The Ohio State University, is the first of its kind to look at the ways electroceutical bandages kill bacteria around a wound, allowing wounds to heal faster. Electroceutical bandages have been used to treat wounds since at least 2013.
New Technology That Prints Human Skin Could Help Hasten Wound Healing
Scientists have developed a new technology that can print human skin, layer by layer, to cover and treat large wounds or burns faster than traditional treatments. A team from Wake Forest Institute for Regenerative Medicine (WFIRM) created the mobile skin bioprinting system that uses a patient's own cells to produce skin tissue that will directly cover wounds, EurekAlert reported Thursday. Researchers said in a report published in the Scientific Reports journal that doctors can easily move the wheeled technology to any place because of its mobility. "The unique aspect of this technology is the mobility of the system and the ability to provide on-site management of extensive wounds by scanning and measuring them in order to deposit the cells directly where they are needed to create skin," Sean Murphy, a WFIRM assistant professor and lead author of the report, said.

The Therapeutic Promise of Apoptosis
Stem cells are classically defined by their unlimited proliferative potential and capacity to differentiate into diverse cell types. For many years, investigations in the stem cell field have focused specifically on the self-renewal and differentiation aspects, leaving the mechanisms of stem cell elimination relatively unexplored (1). What may at first appear to be a trivial question—how can an “immortal” self-renewing stem cell commit cellular suicide?—struck me as biologically important. Are there distinct mechanisms enabling such elimination, I wondered, and, if so, to what extent does this process affect tissue regeneration?

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