NIDDK 75th ANNIVERSARY COLLECTION | | |
In celebration of National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 75th anniversary, a collection of review articles and commentaries is online at Diabetes and Diabetes Care! The series illustrates important scientific and medical progress in understanding, preventing, and treating diabetes.
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIView all articles HERE
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIThe HIRN specific article is HERE
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The Human Islet Research Network (HIRN) announces new funding initiatives to support the use of existing HIRN datasets and resources to explore unique and innovative hypotheses designed to accelerate breakthroughs and advances in type 1 diabetes (T1D) research. The Human Islet Research Network (HIRN) Data Scholars Award (DSA) Program provides:
- Funding for data-science centered or driven projects submitted via a streamlined process to the HIRN Human Islet Research Enhancement Center (HIREC). Projects will use existing datasets from HIRN and related T1D partner programs and/or resources to design studies or create resources that are responsive to specific initiatives in this announcement.
- Opportunities to collaborate with HIRN investigators and programs and efficiently exchange ideas and resources to accelerate innovation in T1D research.
Depending on the initiative (there are currently two opportunities), awardees will receive either $50,000 or $1,000. Learn more HERE.
KEY DATES
Posted Date: April 1, 2025
Application Due Date: May 1, 2025; November 1, 2025
Scientific Review: June 2025; December 2025
Start Date: August 2025; February 2026
| | NIH FUNDING OPPORTUNITIES | | |
RFA-DK-26-009: New Investigator Gateway Awards for Collaborative T1D Research (R03 Clinical Trial Not Allowed)
The New Investigator Gateway Award in T1D Research is designed to support a robust pipeline of innovative projects and talented new investigators in T1D research. Embedding awardees within an established scientific framework in each of these consortia will provide unique opportunities for New and Early Stage Investigators to increase their understanding of key questions in the field, to network, and to establish unique and potentially long-lasting collaborations that will propel their careers forward. Bringing New and Early Stage Investigators into existing collaborative research networks also will benefit the networks by infusing new ideas and perspectives. *Foreign applications not allowed.
Application due dates:
- June 26, 2025
- March 6, 2026
PAR-23-237: Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24, Clinical Trial Not Allowed)
- Application due date: Standard Dates
- Foreign applications allowed
| | HELMSLEY FUNDING OPPORTUNITY | | |
The Leona M. and Harry B. Helmsley Charitable Trust’s (Helmsley) Type 1 Diabetes (T1D) Program currently has an open request for proposals to fund T1D innate immunity projects. The Helmsley T1D Program aims to support the discovery and development of new therapies to prevent or delay T1D and the identification and validation of biomarkers to predict disease initiation and progression.
T1D is a complex autoimmune disease where insulin-producing beta cells in the pancreas are targeted by immune cells. The predisposing factors, triggers, and other elements that affect disease pathogenesis in humans are not yet fully identified. Understanding these drivers of disease could lead to discoveries of new drug targets, guide intervention strategies to halt the disease, or improve prediction of disease development.
To date most T1D preclinical and clinical research has focused on the role T cells play in disease pathogenesis. However, innate immune cells are the first and most abundant type of immune cells in the pancreas, especially in individuals with T1D. Moreover, data, mostly generated from animal experiments, suggests that these cells might play different roles in T1D: from activating T cells and/or recruiting them to the pancreatic islets, to promoting inflammation or inducing immune tolerance. However, what leads to an increase in innate immune cells in the pancreas during T1D, its significance, and what role these cells play in disease in humans is not yet fully understood.
Learn More HERE
Concept notes due: April 30, 2025
Full grant proposal due: July 30, 2025
Funding start date: February 2026
| | NOMINATIONS FOR DIABETES TRAILBLAZERS | | |
Nominate someone for the 2025 class of WIELD Diabetes Trailblazers!
Criteria: Women who exemplify excellence in their contributions to obesity, metabolism, diabetes, or endocrinology as well as excellence in mentoring and service to the scientific community should be nominated! Nominees should be Full or Emeritus Professors (or industry equivalent), with >150 publications and an H- or I-Index > 60 or hold an executive leadership in industry. Self-nominations are accepted!
For more information click HERE and submit nomination HERE.
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Two PanKbase MPIs recently presented webinars for dkNET on the use of knowledge graphs in biomedical research. Dr. Jie Liu presented “Building Knowledge Graphs Towards Transparent Biomedical AI”. Information about the webinar can be found HERE. Dr. Jason Flannick spoke about "Using Knowledge Graphs within Biomedical Knowledge Portals: The Biomedical Translator and the Common Fund Knowledge Center". Information about Dr. Flannick’s webinar is HERE. If you missed them, both talks will soon be available on the dkNET Youtube channel.
PanKbase is going to be at the 85th Scientific Sessions of the American Diabetes Association (ADA) as part of the NIDDK Data Science Corner. If you are coming to ADA, stop by the PanKbase booth to learn more about the platform and meet the PanKbase team. Discover new features of PanKbase, ask questions, and give us feedback. We look forward to interacting with the diabetes community at ADA. See you all in Chicago!
Follow PanKbase on social media for additional updates on the program, including X, Bluesky, and LinkedIn.
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The Virtual Diabetes Research Seminar Series began as an effort to connect investigators and trainees during this time of great change and isolation related to the COVID crisis. This seminar series is organized by several NIDDK-funded Diabetes Research Centers. Each Seminar in the series features an outstanding scientist or panel of scientists discussing the latest in diabetes, obesity, or metabolic research.
Speaker: Darko Stefanovski, PhD, Associate professor of Biostatistics, Department of Clinical Studies, New Bolton Center School of Veterinary Medicine, Associate Professor of Pediatrics, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania.
Title: Beyond Insulin: Glucose Effectiveness as a Therapeutic Target for Obesity and Diabetes.
Date: May 14, 2025, 2:00 pm Eastern
Learn more and register HERE
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Presenter: Avi Ma'ayan, PhD, Mount Sinai Endowed Professor in Bioinformatics, Professor in Department of Pharmacological Sciences, and Director of Mount Sinai Center of Bioinformatics, Icahn School of Medicine at Mount Sinai
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIDate: May 16, 2025, 11 am - 12 pm PT
IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIITo register click HERE
| | The 2025 Rachmiel Levine-Arthur Riggs Diabetes Research Symposium will be held in Pasadena, California from November 14-17, 2025. This year’s symposium will highlight the latest developments in type 1 diabetes research and provide opportunity for trainees to present and receive awards. For more information, scan the QR code below or learn more HERE. | | Below is a summary of the most recent job postings by category (Faculty, Research Staff/Admin, Postdoc). Visit the HIRN Website for a full listing of job opportunities. | | |
Assistant or Associate Professor
The University of Florida Diabetes Institute (UFDI), associated with the Department of Pathology, Immunology, and Laboratory Medicine, is seeking applicants for a full-time tenure-track faculty position at the rank of Assistant or Associate Professor. We are seeking candidates with a strong publication record and history of NIH or foundation grant funding in the area of diabetes research or its complications. Individuals who apply for this position should submit a cover letter, a summary statement outlining the focus and future vision for their research program. The applicant will need to provide at least three letters of recommendation from senior scientists. The letters of reference may be uploaded or sent directly to the Director of the UFDI and search committee chair, Dr. Todd Brusko.
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Professor
The Medical University of Graz is looking for an excellent researcher with great potential to develop an internationally recognized research agenda in the fields of (cellular) (energy) metabolism, signaling, molecular biology and biochemistry. The successful candidate is expected to conduct research and teaching in molecular biology and biochemistry, focusing on the function and health of beta cells. The new Tenure Track Professor position will complement the research activities of the Division of Molecular Biology and Biochemistry at the Gottfried Schatz Research Center Graz. The initial appointment is limited to six years. For more information click HERE.
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Staff Scientist
The Mallone & You satellite laboratory has a Staff Scientist position available for a talented individual with training, knowledge and experience in immunology. As a Staff Scientist, the candidate will run the lab locally and lead the research projects at IBRI. The incumbent will design and perform experiments, critically analyze the results obtained, generate reports and use this information to fine-tune the starting hypotheses and design new experiments. Interested applicants please send a cover letter and curriculum vitae, including the names of three references, to Dr. Roberto Mallone.
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Assistant or Associate Professor
Benaroya Research Institute (BRI) in Seattle, WA seeks to recruit several outstanding investigators for new faculty positions at the Assistant or Associate Member level, equivalent to Assistant or Associate Professor. We seek candidates who use innovative experimental and/or computational approaches to study immune system function in health and disease, with a particular emphasis on autoimmune and immune-mediated diseases. Qualified candidates should send an application package comprising a single pdf document including their curriculum vitae, a research describing their research plan and goals, a cover letter describing how their research fits with the focus of BRI, and the names and contact information for at least 3 references HERE.
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Faculty Recruitment
The University of Alabama at Birmingham (UAB) Heersink School of Medicine (Heersink SOM) and the UAB Comprehensive Diabetes Center (UCDC) are continuing the recruitment of up to 10 investigators for a major strategic portfolio increase across basic, translational, clinical, and population science research efforts in diabetes. Of note, one of the priority focus areas is islet biology.
This an open rank recruitment for faculty applicants with an MD, PhD or MD/PhD and includes academic appointment in one or more of 27 academic departments, many of which rank in the top 10 nationally in NIH funding. Successful candidates will join half a dozen recently recruited faculty as well as the rest of the highly collaborative 200 UCDC faculty members.
For a more detailed position announcement and to apply, please visit HERE.
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The University of Florida Diabetes Institute is looking for highly motivated and team-science minded individual with managerial experience, who will serve as the Operational Director of a series of programs at the University of Florida that utilize tissues obtained from organ donors to address important research questions, largely but not exclusively related to diabetes, including its pathogenesis and disease-related complications.
The individual in this position will be involved in programmatic designs and is responsible for implementing the various strategic plans for each program and ensuring their success. Importantly, this individual will be responsible for monitoring grant budgets, negotiating numerous financial and legal contracts, preparing external reports, and supervising local administrative staff. Interested applicants please apply directly through the UF Jobs or send a cover letter and curriculum vitae, including the names of three references to Dr. Mark Atkinson, Institute Director.
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Postdoctoral Position
The Wortham lab at the University of Colorado Anschutz Medical Campus is recruiting a postdoctoral trainee to study how nutrient metabolism impacts regulation of the epigenome to mediate functional adaptations by pancreatic beta cells. Successful candidates will employ combinations of stable isotope tracing, single cell genomics, and physiological studies in mouse models of diabetes and in primary human islets. Trainees in the lab will benefit from strong technical support including animal surgery, tagging, and genotyping, as well as computational analysis. This position will provide opportunities for career development activities pursuant to the trainee’s goals including presentations at regional and national conferences, collaborations within and beyond CU Anschutz, networking opportunities, and focused training in scientific communication including grantsmanship, manuscript preparation, and public speaking. Prior experience in mouse genetics and strong written communication skills are required. A background in genomic dataset analysis is preferred. Interested candidates should send a CV and brief description of research interests to Dr. Matthew Wortham.
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Postdoctoral Position
We are seeking highly motivated, detail-oriented, and collaborative individuals with excellent writing and verbal communication skills to join our research team. Experience in animal physiology, molecular biology, and cell biology are desired. Additional experience in transcriptomics, metabolomics, or bioinformatics are desirable, but not required. A recent PhD in biology or a related field is required. Projects in the laboratory are centered on elucidating the molecular and transcriptional mechanisms involved in the regulation of beta cell proliferation and mitochondrial metabolism, delta cell function, islet paracrine signaling, and stem cell-derived islet generation.
Interested applicants please send a cover letter and curriculum vitae, including the names of three references, to: Dr. Richard Cox.
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Postdoctoral Position
The Integrative Immunology and Cell Design Laboratory at Penn Medicine is seeking postdoctoral fellows to investigate the molecular mechanisms underlying T cell antigen recognition in autoimmunity, cancer, and infectious diseases. Our research employs high-throughput antigen discovery, single-cell genomics, and synthetic biology to map T cell specificity using platforms such as TScan-I (Cell, 2019), TScan-II (Cell, 2023), and TCR-MAP (Nature Biotechnology, 2024). Successful candidates will join a multidisciplinary team to advance our understanding of T cell-mediated immune surveillance and tolerance while contributing to translational research. Interested applicants should send a cover letter, CV, and reference contacts to: Dr. Mohammad Haj-Dezfulian.
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Postdoctoral Position
At the KU Leuven Diabetes Lab, headed by Professor Dr. Chantal Mathieu and Dr. Conny Gysemans, are dedicated to preventing and treating type 1 diabetes through pioneering research and global collaborations. We are looking for an interdisciplinary scientist that is eager to develop approaches to analyze and integrate mouse and human single-cell, single-nucleus, and spatial data across modalities and apply these methods to further progress our understanding of type 1 diabetes development and propose therapeutic options. Interested applicants please send a cover letter and curriculum vitae, including the names of three references, to Dr. Chantal Mathieu.
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Postdoctoral Position
The University of Michigan Multidisciplinary Training Program in Basic Diabetes Research seeks applicants for an NIH-funded postdoctoral trainee position. The primary goal is to develop trainees to have a deep understanding of the molecular aspects of diabetes and to prepare Ph.D. basic scientists for research careers in Type 1 and Type 2 diabetes. Our training program includes mentors in the area of pancreatic beta cell biology as well as other molecular and cellular aspects of diabetes science. Training is a combination of immersion in specific laboratory-based research projects, formal education, mentorship, and participation in a variety of other research-related educational activities. This program has a track record of success for all of its former trainees. Interested applicants please send a cover letter and curriculum vitae, including the names of three references, to Dr. Peter Arvan.
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