HIRN Network





The following trainees are recipients of the HIRN 2022 Scholarship based on competitive review of abstracts by members of the

HIRN Planning Committee.

Abhishek Kulkarni, PhD

University of Florida

Postdoctoral Research Fellow

CBDS/CHIB (PIs: Mirmira/Brusko)

Gregory Golden, PhD

University of Pennsylvania

Postdoctoral Researcher

CMAI (PI: Betts)

Olha Melnyk, PhD

Indiana University

Postdoctoral Research Fellow

CBDS (PI: Linnemann)

Ali Shilleh

Univ. Colorado Anschutz Campus

Graduate Student

CBDS (PI: Russ)



The following trainees were selected as award recipients based on the posters they presented at the HIRN 2022 Annual

Investigator Meeting.

Cristiane dos Santos, PhD

Vanderbilt University

Postdoctoral Research Scientist

CBDS (PI: Rafael Arrojo e Drigo)

Vrushali Agashe, PhD

Columbia University

Postdoctoral Research Scientist

CMAI (PI: Megan Sykes)

Udi Ehud Knebel

Hebrew University of Jerusalem

Doctoral Student

CBDS (PI: Yuval Dor)

Leslie Wagner

Indiana Univ. School of Medicine

Doctoral Student

CBDS (PI: Amelia Linnemann)


The following individuals received HIRN Catalyst Awards based on competitive review of their proposed applications. The goal of this initiative was to support investigators developing bold, innovative, and challenging projects that will catalyze the field and provide important advances in topics of interest to the network. 

Wen-Hong Li, PhD

Univ. Texas Southwester Med Ctr

Ultra-sensitive Probes for High Resolution Imaging of Hormone Secretion in Islet Cells of Physiological Preparations” (HPAC)

Jeffrey Millman, PhD

Washington Univ. School of Med

Epigenomic Engineering of

Stem Cell-Derived Pancreatic Cells” (CHIB)

Lori Sussel, MD

Univ. Colorado Anschutz Campus

Lactate-mediated Metabolic Reprogramming of Beta Cells in T1D Contributes to their Enhanced Plasticity and Dedifferentiation” (CBDS)

Qizhi Tang, PhD

Univ. California San Francisco

Tregs as Vehicles for Targeted Delivery of Therapeutic Payload to Human Islets” (CTAR)


dkNET is an information hub for the DK community, providing regular updates, webinars and new tools and services to support your research, including funding opportunities available, and to help researchers navigate and comply with new regulations and mandates on resource authentication and data sharing. dkNET will be hosting two Webinars:

"Discovering and Evaluating Antibodies, Cell Lines, Software Tools, and Others." Presented by: Jeffrey Grethe, dkNET Co-Principal Investigator. PhD, University of California San Diego.  October 28, 2022, 11 am - 12 pm PT. Click HERE for more information. 

"The Accelerating Medicines Partnership Common Metabolic Diseases Knowledge Portal: a resource for research into the genetic and genomic basis of diabetes and cardiometabolic disease." Presented by: MacKenzie Brandes, Project Manager, Broad Institute.  November 18, 2022,

11 am - 12 pm PT. Click HERE for more information. 


This Funding Opportunity Announcement (FOA) invites applications for the Consortium on Targeting and Regeneration (CTAR) that supports the development of innovative strategies to increase or protect functional human beta cell mass in patients with Type-1 Diabetes (T1D) through controlled manipulation of beta cell replication or islet cell plasticity, reprogramming of non-beta cells into beta-like cells, or shielding of residual beta cell mass from the autoimmune environment. CTAR is a consortium within the Human Islet Research Network (HIRN).

RFA-DK-22-009: Human Islet Research Network - Consortium on Targeting and Regeneration (HIRN-CTAR) (U01 Clinical Trial Not Allowed)

  • Application due date:  October 27, 2022 
  • Foreign applications are not eligible

RFA-DK-22-018Human Islet Research Network (HIRN) Pancreas Knowledgebase Program (PanKbase) (U24 - Clinical Trial Not Allowed)

  • Application due date: March 31, 2023 
  • Foreign applications are not eligible

RFA-DK-22-022: Integrated Physiology of Exocrine and Endocrine Pancreas in Type 1 Diabetes (R01 - Clinical Trial Not Allowed)

  • Application due date:  February 22, 2023 
  • Foreign applications are not eligible

RFA-DK-21-030: New Investigator Gateway Awards for Collaborative T1D Research (R03 Clinical Trial Not Allowed)

  • Application due date:  March 20, 2023 
  • Foreign applications are not eligible

PAR-20-140: Catalytic Tool and Technology Development in Kidney, Urologic, and Hematologic Diseases (R21 Clinical Trial Not Allowed)

  • Application due date:  Standard dates apply
  • Foreign applications are eligible
The Innovative Science Accelerator Program (ISAC) new funding program.
The ISAC Program supports truly innovative, disruptive, risky research to accelerate breakthrough discoveries.
ISAC provides:
  1. Funding for small high-risk/high reward projects via a streamlined process to support cutting-edge research and accelerate true innovation in scientific areas of interest to the Kidney-Urologic-Hematologic (KUH) research communities.
  2. Collaboration and Events for researchers and trainees to efficiently exchange ideas and resources to accelerate innovation.
Applications can be submitted to the ISAC web portal at any time. The review of submitted applications will occur three times a year and provide a quick turnaround from review to award.
  • Application Final Submission: Dec 15
  • Peer Review: Jan
  • Notification of Award: Feb
Learn more HERE
Below is a summary of the most recent job postings by category (Faculty, Research Staff/Admin, Postdoc). Visit the HIRN Website for a full listing for job opportunities.

iPS Core Manager

A iPS Core Manager position in available at the Kulkarni Lab at Joslin Diabetes Center, Harvard Medical Center. The Core Manager will set up the infrastructure, equipment and supervision of the functionality of generating human iPS cells from patient samples in the long-term goal of generating insulin-secreting beta-like cells for testing in ex vivo and in vitro studies. This role will primarily be responsible for supervising the laboratory as well as having the expertise to undertake hands-on work if necessary, to insure timely progress of the projects. Applicants for the position should provide a brief statement of research interests, CV and the names of three references to Dr. Rohit Kulkarni

Assistant Scientist
The University of Miami, Department of Medicine has an exciting opportunity for a Full-Time Assistant Scientist to work on the UHealth Campus. The Assistant Scientist carries out a particular research agenda in support of the University’s research goals and objectives. Moreover, the Assistant Scientist contributes to the scientific community by publishing research findings and promotes the University’s reputation as a leader in the field. For more information and official job posting, please contact Dr. Werneck de Castro.

Postdoctoral Position

The Integrative Omics Group at PNNL is seeking postdoctoral fellow to join our multi-disciplinary team with a focus on mass spectrometry-based omics analyses. The postdoc will be working across multiple cutting-edge and synergistic NIH-funded projects on human physiology and metabolism. The individual will be performing a single or a combination of deep mass spectrometry-based omics (proteomics, lipidomics, metabolomics, and/or analysis of post-translational modifications) and functional and analyses of cells, tissues, protein complexes, and biofluids to discover and probe novel mechanistic pathways that drive normal human development and dysregulations that contribute to diseases. Interested candidates should send their CV, cover letter, a brief statement of their research interests, and three references to Dr. Ernesto Nakaya

Postdoctoral Position

The laboratory of Dr. Audrey Parent at the University of California, San Francisco is seeking postdoctoral fellows interested in developing immune evasion strategies for beta cell replacement therapy. Our research program is diverse, combining directed differentiation of human pluripotent stem cells into pancreatic beta cells and thymic epithelial cells with genome engineering approaches to study autoimmunity in humanized models. Selected candidates will work in a collaborative and interdisciplinary team and will be encouraged to develop their own research interests. Candidates must have a PhD in biology, immunology, or a related field. Applicants for the position should send a CV, a brief statement of their research interests, and contact information for three references to Dr. Audrey Parent.

Postdoctoral Position

The University of Miami, Department of Medicine, division of Endocrinology is seeking a Post Doctoral Associate that will support investigations that focus on understanding the molecular mechanisms that govern growth and survival of islet b- cells. The candidate will perform scientific research and studies under the supervision of managing staff. They will investigate the molecular and cellular biology of how insulin producing cells grow and die and how they adapt to diabetogenic conditions. Perform a variety of complex technical duties involved in conducting physical, chemical, biological and other research laboratory tests.  For more information and official job posting, please contact

Dr. Werneck de Castro.

Postdoctoral Position

The Almaça lab in the Division of Endocrinology, Diabetes and Metabolism in the Department of Medicine at the University of Miami Miller School of Medicine (UM) is seeking a highly motivated post-doctoral fellow to join their enthusiastic and energetic research team. The overall goal of the Almaça lab is to define the role of blood vessels in the regulation of hormone secretion from pancreatic islets. Much of the work will be focused on studying the physiology of islet pericytes and endothelial cells and examining their impact on endocrine cell function. The successful applicant for this position should have a Ph.D. degree and a background in physiology and functional imaging approaches. Applicants should provide a brief statement of their research interests, CV, and the names of three references to Dr. Joana Almaça.

Postdoctoral Position

The Tang lab at UCSF is looking for two postdoctoral fellows to work on projects on improving beta cell replacement therapy by promoting beta-cell survival in ischemia and developing local immune modulation strategies to avoid systemic immunosuppression. The ideal candidate should have experience in type 1 diabetes research, knowledge of transplant immunology, animal modeling, and enthusiasm for novel therapeutic development. The Tang lab is located in the UCSF Diabetes Center among a group of highly collaborative labs with expertise in immunology, stem cell biology, and beta-cell biology. Please contact Dr. Qizhi Tang for more information.

Postdoctoral Position
The laboratory of Dr. Yumi Imai in Internal Medicine at University of Iowa is recruiting postdoctoral fellows to join a dynamic and innovative research team that is a part of Fraternal Order of Eagles Diabetes Research Center. Research at Imai lab dissects pathogenesis of islet dysfunction in type 2 diabetes with a focus on lipid metabolism. Applications are invited from highly motivated candidates with Ph.D. and/or M.D. degrees. Expertise and skills in islet study, imaging, lipidology, and diabetes are highly relevant, but not required. In this position, you will address how production and clearance of lipids are regulated in pancreatic islets in health and deranged in diabetes using rodent and human islet models in vitro and in vivo. Candidates will also be encouraged to develop their own research projects. Interested candidates should send their CV, cover letter, a brief statement of research interest, and contact information with 3 references to Dr. Yumi Imai.
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