HIRN Network
SEPTEMBER 2019
NEWSLETTER
Get to know our HIRN Projects
Contact PI : Ben Stanger, MD, PhD
University of Pennsylvania (UG3 DK122644 )

Project Summary: The ability to interrupt immune-mediated destruction of beta cells in type 1 diabetes will require a detailed understanding of the underlying cellular and molecular mechanisms. This project aims to use sophisticated “organ-on-a-chip” approaches to model immune-mediated destruction of islets using engineered cells and patient samples.
HIRN Investigator receives 2019 Jacobaeus Prize
Imaging the Pancreas in Diabetes, and Benign and Mailgnant Exocrine Pancreatic Disease

Date: January 13-14, 2020
Location : Natcher Conference Center, Bethesda, MD

Strategies for Clinical Imaging in Diabetes

Date: January 15, 2020
Location : Natcher Conference Center, Bethesda, MD
NIH Requests for Applications (RFAs)

F31 PAR-19-378 : Bioinformatics Interdisciplinary Predoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases  
  • Application Due Date:  Standard dates apply 
  • Foreign applications allowed

F32 PAR-19-379 : Bioinformatics Interdisciplinary Postdoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases 
  • Application Due Date:  Standard dates apply 
  • Foreign applications allowed

RFA-GM-19-001: Methods to Improve Reproducibility of Human iPSC Derivation, Growth and Differentiation (SBIR) (R44 – Clinical Trial Not Allowed) 
  • $500,000 in direct cost per year for 5 years
  • Application due date: January 6, 2020
  • Foreign applications are not allowed

RFA-RM-19-014: Catalyst Award In Diabetes, Endocrinology and Metabolic Diseases  
  • $500,000 in direct cost per year for 5 years
  • Application due date: December 3, 2019
  • Foreign applications are not allowed

RFA-PAR-18-886 : New Par adigms in Tissue Communication-from mediators to metabolic function (RC2 Clinical Trials Optional)
  • Letter of Intent due: Six weeks prior to application due date
  • Application due dates: October 31, 2019; June 2, 2020
  • Foreign applications are not allowed
NIH Requests for Information (RFI)

NOT-DK-19-024 : Bioinformatics/Computational Needs for NIDDK Investigators Engaged in Diabetes, Endocrinology and Metabolic Diseases Research
  • Response Date: October 15, 2019
dkNET Funding Opportunities

  • $50,000 over one year
  • Application due date: December 4, 2019
JOB OPPORTUNITIES
Visit HIRN Website to view full posting details
Postdoctoral Position

The laboratory of Dr. Amelia Linnemann at the Indiana University Center for Diabetes and Metabolic Diseases has an opening for a PhD and/or MD postdoctoral research scientist to develop intravital microscopy techniques for pancreatic islet imaging, to build upon our recently published work (see Reissaus et al , Scientific Reports 2019 ). Interested applicants are encouraged to send an updated CV and names of 3 references to Dr. Amelia Linnemann , PhD, Assistant Professor, Department of Pediatrics, Indiana University School of Medicine.
Program Directors

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is seeking a Clinical Health Psychologist to lead a program of behavioral research on diabetes within the Division of Diabetes, Endocrinology and Metabolic Diseases (DDEM). The DDEM supports and provides leadership for research on the causes, prevention and treatment of diabetes and its complications, as well as other endocrine and metabolic diseases.

The NIDDK is seeking a Ph.D.- level scientist to lead a program of research on the neurobiology of energy balance and metabolic diseases within the Division of Diabetes, Endocrinology and Metabolic Diseases (DDEM). The DDEM supports and provides leadership for research on the causes, prevention and treatment of diabetes and its complications, as well as other endocrine and metabolic diseases.

Physician to Oversee Diabetes Clinical Studies
The NIDDK at the NIH is seeking a talented Physician (M.D. or equivalent) with expertise relevant to type 1 and/or type 2 diabetes research to manage clinical studies and trials related to the prevention and treatment of diabetes and its complications. This position offers unique and exciting opportunities to provide scientific leadership and to administer grants in support of diabetes research in the US.

Faculty Positions

The  Diabetes Center of Excellence at the University of Massachusetts Medical School  invites applications for a SENIOR TENURED or JUNIOR TENURE-TRACK basic science or clinical investigator faculty position. The position will be highly competitive with regard to start-up funds, laboratory space (if needed) and salary. The Center seeks an individual of outstanding research potential relating to diabetes pathophysiology or treatment. 
Faculty Positions

The  University of California, San Diego   Department of Pediatrics is recruiting two tenure track faculty positions. An Associate or Full position in the area of basic biology of diabetes and metabolic disease. This is broadly interpreted to include individuals in the fields of cell biology, stem cells, immunology, genetics, or bioengineering, interested in studying disease-relevant mechanisms.

An Assistant position in the area of basic biology of diabetes and metabolic disease. This is broadly interpreted to include individuals in the fields of cell biology, stem cells, immunology, genetics, or bioengineering, interested in studying disease-relevant mechanisms.
Assistant & Associate Member
The Diabetes Clinical Research Program (DCRP) at  Benaroya Research Institute  seeks to recruit outstanding applicants for a new faculty position. The appointment will be at the at the assistant, associate or full member level, commensurate with experience, training and achievement.
The  University of Miami Miller School of Medicine  Department of of Microbiology and Immunology is accepting applications for Assistant and Associate Professor level for investigators with research interests related to immunotherapy of cancer, autoimmunity, or infectious diseases. Applicants should have a Ph.D., M.D. or equivalent, at least 3 years of postdoctoral training.
Interested in small-molecule discovery and modulating beta-cell phenotypes? The Wagner lab in the Chemical Biology & Therapeutics Science (CBTS) Program at the Broad Institute , is accepting applications for postdoctoral fellow positions. We are looking for researchers interested in studying small molecule-mediated beta-cell proliferation and insulin secretion.
Applications are invited for prospective Post-Doctoral Fellows to train at the Joslin Diabetes Center , Harvard Medical School. Applications are invited from qualified individuals with a PhD or MD or MD PhD degrees and interested in working in the Kulkarni Lab on projects focused on defining pathways and mechanisms that regulate pancreatic (endocrine and exocrine) biology and interrogating inter-organ cross talk in the overall maintenance of glucose homeostasis.
The Tang lab at UCSF is looking for a postdoctoral fellow to join the efforts on optimizing beta cell replacement therapy in preclinical mouse models. 
Postdoctoral position in the Lab of Dr. Sangeeta Dhawan at the  Beckman Research Institute  at  City of Hope , in Los Angeles county, CA to study the epigenetic regulation of pancreatic beta cell mass. The candidate should have a PhD in molecular, cell, or developmental biology. Experience in genetic mouse models, islet biology, physiology, molecular biology, high throughput sequencing is desirable. 
Postdoctoral position in the Lab of Dr. Doris Stoffers in the   Institute for Diabetes, Obesity, and Metabolism  within the  Perelman School of Medicine  at the  University of Pennsylvania . A PhD is required; experience in genetic mouse models, islet physiology, advanced molecular techniques, high throughput sequencing methodologies and bioinformatics, proteomics, metabolomics is helpful. 
Postdoctoral Position
The  Lab of Dr. Abdelfattah El Ouaamari   at  Rutgers University/Robert Wood Johnson Medical School is recruiting self-driven, creative and organized candidates with a PhD in neuroscience, biochemistry or molecular and cellular biology. The candidate must possess skills in manipulating and assessing neuronal activity.