Innovating at the Intersection of Proteogenomics and DNA Analysis.
Touch samples can be critically important to criminal investigations yet are the most challenging to analyze due to degradation or an insufficient amount of deposited DNA.
Though DNA analysis is the gold standard for human identification, the CAG is working to develop new methods based on proteomics.
Our Proteo-ID team, including collaborators from UNT Health Science Center and Ohio State University, has developed a method to co-extract DNA and the more robust proteins found in large quantities in touch samples. The method preserves the DNA for traditional analysis and enables insight from the proteins through proteolytic digestion and analysis via standard liquid chromatography-tandem mass spectrometry-based proteomics.