HUPOST Editor: Aleksandra Nita-Lazar | Staff Editor: HUPO Office | July 2024
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Register Now and Save
Secure your spot at HUPO 2024 and take advantage of our early registration discounts:
- Early Bird Fee: Until July 15
- Regular Fee: Until August 15
- Late Fee: From August 15 onward
Abstract Submissions Closed
HUPO 2024 extends sincere thanks for the numerous contributions to the program. Abstract review is in full progress. Notices will be distributed at the end of July advising if a submission has been accepted as an oral or poster presentation.
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Program is Online!
See the final scientific program here. You can expect a wide variety of outstanding symposia, engaging plenary and keynote talks, pre-workshops, and much more.
Social Program
Be sure to sign-up for a variety of opportunities to mingle and network with colleagues and friends:
- Welcome Networking Reception in Exhibit Hall
- Early Career Researcher Networking Night: Boat Tour on the beautiful River Elbe
- Congress Dinner on the Terrace level of the Maritim Hotel
- Social Networking Event with music, dancing and much more!
Tickets for all events can be purchased during the registration process. More information will follow soon!
Accommodation at Maritim Hotel
Book your stay at the Maritim Hotel with exclusive rates and save time travelling to the congress venue every morning, as the Maritim Hotel is part of the exhibition and program venue.
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HUPO is inviting candidates to serve on the HUPO Council for a three-year term that will begin in January 2025 (2025-2027).
Serving in a leadership capacity as a Council Member increases your connections and professional profile throughout the proteomics community. It's an excellent opportunity to contribute your expertise and ideas to advance the direction of HUPO and its strategic plan. Each councilor must be an active (paid) HUPO member who is a scientist from the public or private sector with professional experience in educational, research, or commercial activities related to the purposes of HUPO.
The current Council list can be seen here.
Deadline for all nominations is July 8, 2024 (23:59 pm PDT).
For questions or further information, please contact the HUPO Office office@hupo.org
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In recognition and appreciation of the significant support, participation and guidance provided by HUPO's Industrial Advisory Board (IAB), one IAB member is highlighted each month. We encourage you to connect with these companies directly for further information about their involvement in HUPO and their products and services. |
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Pelago Bioscience is a CRO supporting all phases of drug discovery, with expertise in target engagement in biologically relevant assay systems. We believe that all drug discovery projects should know their target(s) before entering the clinic. To fulfill this mission, we utilize our patented core technology, CETSA® (Cellular Thermal Shift Assay), essential for early decision-making throughout the entire drug discovery pipeline.
CETSA measures the thermal stability of proteins in response to compound binding in a completely label-free manner. It offers multiple assay formats, from confirming target engagement and validating targets to generating hits for challenging targets and elucidating compound mechanisms of action. CETSA also excels in understanding the selectivity profile of compounds in biologically relevant models.
Target Deconvolution with CETSA: Uncover your drug candidate's interactions with targets through comprehensive, proteome-wide analysis. This combines CETSA with mass spectrometry, delivering unbiased results covering over 7,000 proteins without modifications to your compound or target proteins. Identify both on-target and off-target interactions in biologically relevant cell systems, providing crucial insights for target identification and mechanism of action studies.
Primary Screening with CETSA: Accelerate your lead generation process by identifying high-quality chemical starting points with high-throughput screening. Benefit from rapid assay development, high-throughput screening for challenging targets, and identification of high-quality hits for further development, saving time and money while reducing attrition rates.
Hit Confirmation with CETSA: Validate your selected target protein's binding to a compound in its native state. This service assesses compound binding without modifications to the protein or compound, ensuring accurate target engagement assessment and helping you prioritize promising drug candidates.
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Robust Target Engagement Assessment: Gain confidence in your drug targets, ensuring candidates engage with intended targets in a biologically relevant context.
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Breakthroughs for Challenging Targets: Identify promising drug candidates for targets traditionally deemed "undruggable," unlocking new therapeutic possibilities.
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Deep Mechanistic Insights: Understand the precise mechanisms of action of your compounds, illuminating interactions with targets and broader cellular pathways.
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Comprehensive Selectivity Profiling: Assess compound specificity against potential off-targets in biologically relevant models, minimizing unwanted side effects.
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Pelago Bioscience's team of seasoned scientists collaborates closely with you to deliver actionable insights, enabling confident asset prioritization in your drug discovery pipeline. Our expertise, over a decade of experience with more than 220 customers including leading pharmaceutical companies, and powerful CETSA technology make us your trusted partner in accelerating drug discovery.
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Congratulations to the Finalists of the Manuscript Competition
The manuscript competition is a unique opportunity for early career researchers to gain visibility in the proteomics community, as it serves as a platform to highlight the important contributions that postdoctoral fellows, young clinicians and junior faculty members make to the proteomics field. Three finalists have been selected to present their publications in a dedicated plenary session at HUPO 2024, where an expert committee will evaluate the oral presentations to determine the “Proteomics Highlight of the Year” by an ECR. Congratulations to all finalists:
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Leyuan Li (Beijing Proteome Research Center, CN) - Revealing proteome-level functional redundancy in human gut microbiome using ultra-deep metaproteomics
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Stacy Malaker (Yale University, USA) - Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE
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Marc van Oostrum (Max Planck Institute for Brain Research, Germany) - The proteomic landscape of synaptic diversity across brain regions and cell types
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Join Us for the HUPO Early Career Researchers Networking Night at HUPO 2024 World Congress
Sunday, October 20th 19:30-22:30
Early career researchers and senior scientists are welcome to join this exciting event, which aims to bridge digital, cultural, and continental gaps. The ECR Networking Night provides a fantastic opportunity for early-stage researchers to meet, share, and connect with colleagues and senior researchers.
This year, the evening will feature a scenic boat ride around Dresden, offering stunning views, beverages and a chance to mingle in a relaxed atmosphere. It's the perfect setting to network with peers and mentors from around the world. Be ready to meet new people and participate in engaging activities!
Register here for the ECR Networking Night and reserve your ticket now, as space is limited! |
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Chromosome Team Leadership
Good news: Drs. Allan Stensballe and Louise Bundgaard, both excellent scientists, will lead the Chromosome 2 team representing Denmark. Now all our chromosomes have a team!
C-HPP Workshops
We are announcing two Chromosome-Centre Human Proteome Project (C-HPP) Workshops for 2024 and one for 2025:
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26th C-HPP Workshop: (0.5 day), Dresden, Sunday 20th October 2024, 10:00 AM – 15:00 PM (before HUPO Congress).
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27th C-HPP Workshop on the new Human Proteome Project Portal, China, November 2024.
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28th C-HPP Workshop: The HPP Grand Challenge, Saint-Malo, France, June 13-15, 2025 (before EUPA).
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Date: November 18-19, 2024
Location: Aerial UTS Function Centre, Ultimo, Sydney, Australia
Organized By: Children Medical Research Institute, ProCan
Through this two-day meeting, internationally renowned experts in proteomics, genomics, cancer management, biomarker and drug discovery will share their progress towards addressing the challenges and opportunities of multi-omic data integration in cancer management, with a special focus on the role of proteomics in advancing biomarker development and drug discovery.
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Highlighting a member of HUPO, we invite a diverse group of researchers from different career stages, disciplines, geographical locations, and ethnicities to submit a profile for our monthly spotlight. This initiative aims to improve visibility of HUPO members, advertise research, and enhance the HUPO community. This month we are featuring: |
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Mariette Matondo, Paris, France
What is your current position and location?
How did you get started in the field of proteomics?
I began my journey in proteomics in 2005 as a Master's student with Anne Gonzalez de Peredo in the Mass Spectrometry and Proteomics Laboratory led by Dr. B. Monsarrat at IPBS-CNRS in Toulouse. This was the only research and proteomics facility in Toulouse at the time. I continued in this lab as a Ph.D. student under the supervision of Dr. B. Monsarrat and Dr. O. Burlet-Schiltz. I was fortunate to work with one of the first Orbitrap mass spectrometers. My Ph.D. project focused on determining differentially regulated proteins upon proteasome inhibition in AML cell lines through a combination of large-scale and targeted quantitative proteomics. After earning my Ph.D., I joined Dr. Ruedi Aebersold’s lab at ETH Zurich as a postdoc, where I further specialized in targeted proteomics using SRM and continued my research in the field of MS-based proteomics. Since September 2013, I have been leading the Proteomics Core Facility at the Institut Pasteur.
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The HUPO Education and Training Committee (ETC) and the Early Career Researcher Committee (ECR), as well as other HUPO Initiatives (e.g. B/D HPP, Single Cell) have been hard at work organizing and providing very helpful and interesting webinars for the proteomics community. Recordings of these webinars can be found on the HUPO website here.
If you have any ideas or suggestions for webinar topics, please send an email to the HUPO Office and we’ll be sure to pass them along!
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(South Tyrol, Italy)
(Munich, Germany)
(Lille, France)
(Dresden, Germany)
(Sydney, Australia)
(Saint-Malo, France)
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The job board on the HUPO website is a valuable resource for both employers and individuals seeking ideas and opportunities.
If you have a job posting and would like to advertise it, send your information to office@hupo.org. For more information and job listing details - visit the website here.
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Disclaimer: HUPOST provides general information for subscribers. Submissions are welcomed from HUPO members. Articles are to be submitted to HUPO office by 20th of each month (date subject to change without notice) for review by the Editor for suitability. HUPO assumes no liability for errors or omissions in the contents. |
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