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HaemInsights

Issue 2 | February 2025

Welcome to HaemInsights with a focus on Hereditary Spherocytosis (HS). Hereditary Spherocytosis (HS) comprises a diverse group of disorders characterised by the presence of spherocytes. Clinical manifestations may include anaemia, jaundice, reticulocytosis, and splenomegaly. 

Case Study - Hereditary Spherocytosis:

An overview of the clinical features, laboratory findings, and treatment

See results from a 45 year old female…

Quiz

The Levey-Jennings (L-J) plot is a fundamental tool in laboratory quality control, used to monitor the precision and accuracy of test results over time.

In the context of a Full Blood Count (FBC) analyser, results that trend outside the expected range can indicate systematic errors such as bias or random errors affecting test accuracy. Test your knowledge in this quiz.

Last issue's quiz answer is also revealed here!

Bibliography

• Blood Cells A practical guide – Barbara Bain
• Guidelines for the diagnosis and management of Hereditary Spherocytosis
• A BMJ Guideline publication
• https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1365-2141.2004.05052.x

Editorial Team

Kelly Duffy, Andrew Fisher, HORIBA UK Limited

Back Issues

Past issues of Heme Insights are available on our website.

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