As the new year begins, we take a moment to celebrate what’s ahead in in 2025 and the many opportunities for technology advancement and collaboration in HP C-13 MRI research. In this edition of the newsletter, we gear you up for 2025 with workshop registration reminders, new resources on the website, and great recently released publications.

Our 2025 HMTRC Workshop Early Registration deadline (January 17th) is quickly approaching. Register early using the links below! 

Wishing you a great start to the new year!

The HMTRC team & Collaborators

Hyperpolarized Carbon-13 MRI Technology Development Workshop: April 3-4^th 2025, Pre-meeting Events April 2^nd

Registration Deadlines:

Early Registration: January 17^th

Hands-on Registration Deadline: February 12^th

Those who register by January 17^th will be given priority hands-on session placement. Final hands-on registrations are due by February 12^th. This includes the workshop registration, poster submissions, and pre-meeting registrations.

View Brochure for Full Workshop Details

OR Register Now with links below:

External Registration (non-UC Personnel): HMTRC Workshop Registration Fee: Academic Participant $275, Industry Participant $775. Register Early, for priority hands-on placement (January 17th). Final hands-on registrations due February 12th. No registration at the door. Online registration for external members is available through Eventbrite. VISA, Mastercard, Discovercard and American Express are accepted. The HMTRC Workshop Registration Fee includes hands-on training/demo costs, and related MR scanner, DNP supplies, pharmacy and chemistry costs.

Internal Registration (UC personnel): UC personnel please register through Qualtrics by February 12th. University of California personnel please email hyperpolarizedmri@ucsf.edu if you have any questions.

Pre-meeting Sign-ups (deadline February 12^th): The pre-meeting events will take place on Wednesday April 2^nd which will occur the day before the 2025 HMTRC workshop (on Thursday April 3^rd and Friday April 4^th). Please register (links above) for the workshop to attend the pre-meeting events. Registration deadline is February 12^th. There is no additional fee to attend the Pre-Meeting events. Please see the pre-meeting schedule (below) for a list of events happening, participation, and what to bring.

Poster Presenters Submit Title & Authors (deadline February 12th) : We welcome poster presentations by any participants. To register your poster for the 2025 HMTRC workshop, please provide the title and author information through this link by February 12th 2025 if you would like it to be included in the printed materials. You must be able to print your poster prior to the event and bring it on site. We recommend having posters fit within a 36” x 48” size in a landscape orientation. For any questions email hyperpolarizedmri@ucsf.edu.

Book your Workshop Travel Accommodations: See our recommended nearby hotels: Traveling to the Workshop? Book your hotel accommodations at a discounted rate or choose from one of our recommended hotels within miles to the UCSF Mission Bay Campus or the San Francisco International Airport.

About the Update:

Building upon the simple digital metabolic phantoms in the toolbox, we have implemented new anatomically-derived digital phantoms. Based on open-source atlases, BrainWeb^1-7 and Cardiac Atlas Project^8-11, realistic brain and cardiac phantoms are now available. This realistic phantom framework supports the independent definition of kinetic rates, perfusion and bolus timing for separate tissue compartments. Additional modulation of spatial resolution, simulated coil shading and a variety of phantom models allows for dynamic generation of metabolite images that can be used for testing and validating acquisitions, reconstructions and post-processing pipelines.

Three examples of simulated anatomical brain phantom datasets and two examples of in vivo datasets:

An example of simulated anatomy-derived metabolic heart phantom datasets and an example of in vivo datasets. 

How to Access:

Questions? Problems Accessing? Email: hyperpolarizedmri@ucsf.edu

Collaborate with us:

Have your own realistic phantoms that you would like to share, issues or feature requests? Send an email to hyperpolarizedmri@ucsf.edu.

Supporting Information:

1. Aubert-Broche B, Evans AC, Collins L. A new improved version of the realistic digital brain phantom. NeuroImage. 2006;32(1):138-145. doi:10.1016/j.neuroimage.2006.03.052

2. Berengere Aubert-Broche, Griffin M, Pike GB, Evans AC, Collins DL. Twenty New Digital Brain Phantoms for Creation of Validation Image Data Bases. IEEE Trans Med Imaging. 2006;25(11):1410-1416. doi:10.1109/TMI.2006.883453

3. Cocosco C, Kollokian V, Kwan R, Evans A. BrainWeb: Online Interface to a 3D MRI Simulated Brain Database. NeuroImage. Published online 1997. Accessed April 17, 2024. https://www.semanticscholar.org/paper/BrainWeb%3A-Online-Interface-to-a-3D-MRI-Simulated-Cocosco-Kollokian/2bb7426e6ecdab0f120c89f6a324cf0c2a7266d4

4. Collins DL, Zijdenbos AP, Kollokian V, et al. Design and construction of a realistic digital brain phantom. IEEE Trans Med Imaging. 1998;17(3):463-468. doi:10.1109/42.712135

5. Kwan RKS, Evans AC, Pike GB. MRI simulation-based evaluation of image-processing and classification methods. IEEE Trans Med Imaging. 1999;18(11):1085-1097. doi:10.1109/42.816072

6. Kwan R, Evans A, Pike G. An Extensible MRI Simulator for Post-Processing Evaluation. In: Proceedings of the 4th International Conference on Visualization in Biomedical Computing. Springer-Verlag; 1996:135-140.

7. BrainWeb: Simulated Brain Database. Accessed April 17, 2024. https://brainweb.bic.mni.mcgill.ca/brainweb/

8. Fonseca CG, Backhaus M, Bluemke DA, et al. The Cardiac Atlas Project—an imaging database for computational modeling and statistical atlases of the heart. Bioinformatics. 2011;27(16):2288-2295. doi:10.1093/bioinformatics/btr360

9. Petersen SE, Aung N, Sanghvi MM, et al. Reference ranges for cardiac structure and function using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort. J Cardiovasc Magn Reson. 2016;19(1):18. doi:10.1186/s12968-017-0327-9

10. Mauger C, Gilbert K, Lee AM, et al. Right ventricular shape and function: cardiovascular magnetic resonance reference morphology and biventricular risk factor morphometrics in UK Biobank. J Cardiovasc Magn Reson. 2019;21(1):41. doi:10.1186/s12968-019-0551-6

11. Cardiac Atlas Project: Biventricular PCA Modes (UK Biobank). Accessed June 17, 2024. https://www.cardiacatlas.org/biventricular-modes/

Recent journal articles supported by the center

to inspire & drive your basic and clinical research

 Website  | Email  | BlueSky  

Technology Dissemination |  HP Training Modules | Publications |  Projects   

People  |  Contact Us  | Donate