Hollings Research Headlines // March 2022
Hollings team receives Stand Up To Cancer award
Hollings celebrates getting its first Stand Up to Cancer grant. Leading the study at Hollings are Marvella Ford, Ph.D., and Gerard Silvestri, M.D. They are part of a team recently awarded a $3 million grant that will make Hollings a part of the Southeastern Consortium for Lung Cancer Health Equity (SC3), a group that will focus on why lung cancer continues to be one of the leading causes of death among racially and ethnically diverse populations in the nation. 

The project is a collaboration among Hollings, UNC Lineberger Comprehensive Cancer Center and VCU Massey Cancer Center.
"This is an example of how science can be done in the future."
Dr. Robert Winn, director of VCU Massey Cancer Center and co-investigator, in describing how the study is bringing together a powerhouse of researchers from a wide range of specialties.
Colorectal Cancer Awareness Month
Dr. Raymond N. DuBois looks into a microscope
Study targets better ways to prevent and treat colorectal cancer
A research team led by Hollings Director Raymond N. DuBois, M.D., Ph.D., is working to improve the treatment of colorectal cancer. DuBois' team discovered a series of pathways that shed light on how cancer cells and the immune system work.

“Looking at cancer and immune cell interactions in the early stages of cancer development may provide more answers for the field. Currently, there is very little understanding of what is going on in the immune system in the premalignant stage,” said DuBois.
Research impacting our communities
collage of Hollings Community Health Van sign on van door and middle school boy getting HPV vaccine shot
New study combats HPV vaccine misinformation
Hollings launched its new community health van in Cherokee County, South Carolina. The van provided HPV vaccinations to middle schoolers. It's one way Hollings is hoping to increase vaccination rates.

Hollings researchers were also part of a recent study that looked at ways to combat HPV vaccine misinformation by creating vaccine 'champions.'
Hollings Research Snapshots
New program to increase smoking cessation efforts in 1,500 national cancer centers
Graham Warren, M.D., Ph.D., worked with the American College of Surgeons’ Commission on Cancer (CoC) to develop a smoking cessation study for cancer care centers across the country.

The project, titled “Just ASK,” requires cancer center staff to ask new cancer patients if they smoke and encourages them to help their patients to quit smoking.
Studying ways to improve CAR-T-cell design
Dr. Leo Ferreira in his lab
Leonardo Ferreira, Ph.D., is studying the complex functions of T-cell subsets in anti-cancer and immune tolerance applications. The goal is to lead to the design and development of new immune cell-based therapies.

Ferreira's opinion article was published in Frontiers of Immunology and highlights a weakness in the current CAR-T-cell design.
Multiple myeloma trial explores new approach
Glenn Bachmann stands by a marsh with his wife
The standard of care for multiple myeloma patients after a transplant is to remain on maintenance chemotherapy for the rest of their lives, as long as they tolerate and respond well to it.

Glenn Bachmann is participating in a phase III clinical trial at Hollings that is testing whether a new approach could eliminate the need for maintenance chemotherapy after about two years for patients in deep remission.
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Hollings publications and featured trials
Explore some of our featured trials being offered at Hollings.

Check out the latest publications from doctors and researchers at Hollings.
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