-The 10 RCTs consisted of 800 mostly Caucasian individuals aged 25-50. 30% were women. 90% were normotensive at study onset. Trials lasted between 6-12 weeks.
-The 5 cohorts included 190,000 participants. A single cohort accounted for 155,000 of them. This particular cohort consisted of normotensive, predominately white women, aged 25-55 who drank between 0-6 cups daily.
-Table: Upon adjusting for confounders, daily coffee consumption, irrespective of the volume, had no effect on BP or the risk of developing hypertension.
-In aggregate, the trials were determined to be of low methodological quality and heterogenous. For example, neither cup volume nor its caffeine content was standardized.