Really, a day in Whistler doesn't get any better: talks on the newest results on hypoxia and tumor metabolism from morning till night, and outside the snow falls all day, every day. The joint Keystone Symposia on "Adaptations to Hypoxia in Physiology and Disease" and "Tumor Metabolism: Mechanisms and Targets" in Whistler, British Columbia last week featured both skiing and science, and HypOxygen was honored to be a part of it all.
Joint sessions every day highlighted the many ways in which hypoxia controls gene expression, influences metabolic pathways, and regulates immunological and inflammatory processes, with new data showing how
hypoxia affects the Hallmarks of Cancer. North American HypOxystation users Navdeep Chandel, Nick Denko and Brad Wouters gave talks on respiration, mitochondrial function, and hypoxic regulation of autophagy. European HypOxystation users Almut Schulze, Janine Erler and Ester Hammond spoke about glucose/lipid metabolism, ECM remodeling and DNA replication in hypoxia. Together, a global community of cancer researchers are targeting hypoxia as a key factor underlying tumor genesis and cancer progression.
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Ji Zhang presenting his poster at the Keystone Symposia
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We spoke to many of the Keystone attendees about our i2 Instrument workstation and the H35 HEPA HypOxystation by
Don Whitley Scientific
. The closed workstation format of the HypOxystation provides reliable, contiguous hypoxia down to 0.1% for cells accustomed to the very low oxygen customary in any body tissue, and especially in the tumor microenvironment. Precise oxygen, carbon dioxide, and humidity control within a temperature-controlled environment as well as ample space for cellular manipulation, assays and microscopic observation allow researchers to mimic and monitor physiological conditions. HEPA filtration, sterile steam humidification, and remote parameter monitoring are some of the features that make the HypOxystation so unique.
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Sarah Timpano presenting her poster at the Keystone Symposia
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As Jim Uniacke states in
this
video tutorial on creating physiological oxygen, "It is important to
keep cells in the hypoxia workstation up until the point of lysis, as oxygen can rapidly alter the biochemical properties of these translation factors." His lab has been producing exciting results on translation control at hypoxia with the HypOxystation for several years, earning him the honorary title of "
cancer cells' worst nightmare." Dr. Uniacke and all the other researchers at the Keystone symposia are working on conquering the nightmare of cancer, and HypOxygen wants to assist you in that endeavor where possible.
Visit us at
Hypoxygen.com to find out how our hypoxia workstations can take your cells' breath away.
Want more publications on hypoxia research?
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