ToxTracker is a unique, stem-cell based assay which takes advantage of a Green Fluorescent Protein (GFP) reporter system to identify hazard and mode-of-action (MOA) of potentially genotoxic materials. On July 20th, IIVS was formally awarded ToxTracker Certification by Toxys, a Dutch Biotechnology company and the developers of the assay. The optional ACE (Aneugen-Clastogen Evaluation) extension is able identify test materials genotoxic material which induce polyploidy or interfere with normal cell cycle function.

The Standard Project Submission Form (SPSF) was approved by the OECD in 2017 in expectation of the release of a formal Test Guideline for the assay. Click on the images below for more information or email us at