IIVS August 2023 Newsletter

IIVS, Advancing Science & Animal Welfare Together | August 2023 Issue

IIVS Obtains ToxTracker Certification

ToxTracker is a unique, stem-cell based assay which takes advantage of a Green Fluorescent Protein (GFP) reporter system to identify hazard and mode-of-action (MOA) of potentially genotoxic materials. On July 20th, IIVS was formally awarded ToxTracker Certification by Toxys, a Dutch Biotechnology company and the developers of the assay. The optional ACE (Aneugen-Clastogen Evaluation) extension is able identify test materials genotoxic material which induce polyploidy or interfere with normal cell cycle function.

The Standard Project Submission Form (SPSF) was approved by the OECD in 2017 in expectation of the release of a formal Test Guideline for the assay. Click on the images below for more information or email us at [email protected].

Images kindly provided by Toxys

Visit IIVS at Booth #9 at EUROTOX!

IIVS Receives DEA Approval for Study Conduct with Select Schedule 1 Compounds and Materials

We are pleased to announce that our lab has acquired the State and Federal licenses required to work with several materials and compounds listed on DEA Schedule 1. These include cannabis and Δ⁹-THC and related cannabinoids (DEA Drug Codes 7360 & 7370). Our state-of-the art exposure systems include the Vitrocell^® VC-1 and Cloud which are able to generate smoke and nebulize liquid formulations and permit IIVS to evaluate controlled substance-containing products for many respiratory endpoints, such as cytotoxicity, inflammatory response and oxidative stress. Email [email protected] for more information!

12th Annual World Congress on Alternatives and Animal Use in the Life Sciences

IIVS will be exhibiting and participating in WC12, taking place in Niagara Falls, Ontario from August 27-31. Come find us at booth 40.

IIVS President Amanda Ulrey will be presenting two posters:

*A15: Ensuring the Quality of a Test System Using the Principles of Good In Vitro Method Practices (GIVIMP): A Case Study of Cryopreserved Human Precision-cut Lung Slices (#88)

*A14: Incorporating GIVIMP Recommendations into Method Development, Use, and Transfer (#243)

Finally, IIVS has helped to organize the #UseScienceNotAnimals World Café, taking place Tuesday August 29 from 5:30-7:30. Come join us!

Other Upcoming Events with IIVS Participation

Personal Care Product Council Science Symposium, October 24-25, Arlington, VA

Fragrance Science and Advisory Council Dermal Sensitization Workshop, September 13, Arlington, VA

Research Institute for Fragrance Materials Annual Meeting, September 20, Weehauken, NJ

American Society for Cellular and Computational Toxicology Annual Meeting, October 23-25, Silver Spring, MD

American College of Toxicology Annual Meeting, November 12-15, Orlando, FL

Household and Commercial Products Association Annual Meeting, December 3-6, Orlando, FL

Education & Outreach is a primary component of the Institute’s mission to foster the use and regulatory acceptance of in vitro methods. With more than 25 years of experience in validating and performing non-animal tests in our laboratory, IIVS is uniquely positioned to provide training and science-based advocacy to industry, government and animal protection organizations.

Check out our training options!

The Practical Methods training program provides a variety of education and training opportunities, from in-person intensive hands-on courses to lectures, panel discussions, webinars, and consultations that are relevant across all sectors and can include a range of non-animal methods.

IIVS has recently expanded our training opportunities and created a new training request form. Connect with us to design a training or find out more.

IIVS Holds Hands-On Training

In July, with the support of the PETA Science Consortium International, IIVS hosted four scientists from Brazil for our most recent hands-on Practical Methods training.

Request Training

Advance Registration ends September 15

Find out more and see a draft program

Poster abstracts can still be submitted until September 1

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