Use of Non-animal Skin Sensitization Test Methods
27 May 2020, 10:00am – 11:30am EDT
Co-organized by the PETA International Science Consortium, the US Environmental Protection Agency, and the Physicians Committee for Responsible Medicine, the next webinar in the series will focus on:
- Louis “Gino” Scarano, PhD, US Environmental Protection Agency Office of Pollution Prevention and Toxics (OPPT)
- Hans Raabe, MS, Institute for In Vitro Sciences, Inc (IIVS)
The US EPA Office of Pollution Prevention and Toxics will present an update on their review of non-animal skin sensitization tests received since the release of the 2018 OCSPP draft interim science policy on the use of alternative approaches for skin sensitization.
Hans Raabe will discuss the use of non-animal skin sensitization test methods for US EPA classification. Mr. Raabe will provide an overview of the three currently accepted regulatory test methods (OECD test guidelines 442C, 442D, and 442E) and two Defined Approaches (the AOP “2 out of 3” approach and the KE3/1 sequential testing strategy) accepted by the EPA. He will also discuss standard approaches for chemical ingredient testing as well as assessment of more difficult-to-test mixtures. Emerging methods, such as the SENS-IS test, will also be covered.