IUCr Paper On Adopting Cryo-EM - Reagents Shipping Offer - Are You Attending The IUCr Meeting

MiTeGen - Innovations For Crystallography and Cryo-EM

Making the Leap: Transitioning from X-ray Crystallography to Cryo-EM

As structural biology continues to evolve, many laboratories are integrating cryo-electron microscopy (cryo-EM) alongside traditional X-ray crystallography to tackle large, flexible biomolecular complexes.

In a newly featured IUCr paper, "Breaking barriers: transitioning from X-ray crystallography to cryo-EM for structural studies," researchers provide a practical roadmap of the cryo-EM workflow using the epigenetic regulator ATAD2B as a model system. The authors openly share strategies for overcoming common sample preparation hurdles—including diagnosing heterogeneity, optimizing grid freezing conditions, and removing persistent contaminants such as GroEL.

Whether your lab is just beginning to adopt cryo-EM or looking to refine your vitrification and screening protocols, this paper offers valuable, actionable insights to help streamline your structural determination pipeline.

Read the Full IUCr Paper

Accelerate Your Lab's Adoption of Cryo-EM

Let us help you add cryo-EM to your structural biology toolkit. Tap into our experience helping other labs build successful workflows for solving structures. Schedule a no-obligation virtual meeting where we’ll discuss your research vision, share setup insights, and help you identify the exact tools and instruments you need to achieve reproducible, high-resolution results.

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Stock Up & Save: Limited Time Reagents Shipping Offer

Enjoy free domestic ground shipping or 50% off international economy shipping on all MiTeGen reagents through September 20th. We are making it easier and more cost-effective to stock your lab with the quality reagents your research demands.

Claiming your discount is effortless. When placing orders through our website, your shipping savings are automatically applied at checkout with no coupon code required. For offline purchases or those requiring a purchase order, include the promotional code Discount-Reagents-Shipping on your documentation to ensure our team applies the savings to your invoice.

Shop Reagents Today!

Are You Attending The IUCr Meeting in Calgary?

See the IUCr Floor Plan

Get ready for IUCr 2026 in Calgary! We are proud to be part of this milestone event, where we will showcase our cutting-edge solutions designed to optimize your structural science workflows.

Are you going to the IUCr meeting? Then stop by our booth (#19) to see our newest crystallography and Cryo-EM innovations in action and chat with our team about your lab's unique needs. We can't wait to celebrate the future of crystallography and cryo-EM with you. See you at the booth!

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Did You Know We Are an Official Distributor of Nanosoft Tools?

We are proud of our long-standing relationship as an authorized distributor of Nanosoft products. If you aren’t familiar with Nanosoft, they design, engineer, and manufacture specialized tools and instruments to improve all aspects of cryoEM sample preparation and handling.

Many of these innovations seamlessly complement our MiTeGen line of cryoEM tools and instruments. To ensure you get the best support, our team has received thorough training from Nanosoft on using their products. You can see the full line of Nanosoft tools and instruments by clicking the button below.

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Upcoming Events

$Pittsburgh Diffraction Conference 2026$

The Pittsburgh Diffraction Conference (PDC) is September 15th-18th at SLAC National Accelerator Laboratory. The conference features two parallel scientific sessions, one on life sciences and the other on chemistry and materials science. The conference includes lectures, a poster session, a conference banquet, tours of LCLS and SSRL, and an exhibitors' display. We are sponsoring PDC and exhibiting there.

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The XLEAP Workshop, Synchrotron X-rays for Metals in Plants, Soils, and Environmental Systems, is August 5th-7th at Cornell University. The workshop will explore how advanced X-ray techniques can unlock new insights into complex biological, environmental, and agricultural systems, and discuss the future scientific direction of the XLEAP beamline at CHESS. We are sponsoring XLEAP and exhibiting there.

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Events, Workshops and Conferences

If you are looking for more events, please visit our events page. It lists conferences, workshops, symposiums, user meetings, and more. Attending these events offers an excellent opportunity to learn about new research, techniques, and tools from industry leaders.

Topics include structural biology, material science, crystallography, cryo-EM, beamline research, and more. We sponsor and exhibit at many of these events throughout the year.

Visit The Events Page

Announcing: Yeong Jyi Chemical Apparatus Partnership

To our customers in Taiwan: Yeong Jyi Chemical Apparatus is now formally a distributor of MiTeGen products in Taiwan!

Yeong Jyi and MiTeGen have had a trusted business partnership for many years, and it's our great pleasure to formalize it officially. We strongly believe Yeong Jyi and their staff will represent MiTeGen products with the same level of customer service and care you trust. Their contact details can be found via the link below.

Our International Distributor Page

Have your lab be the first to know. Follow us on social media!