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HemoGenix® has developed several proprietary assays for in vitro immunotoxicity high-throughput screening and testing as well as other immune assays involving T- and B-lymphocytes and subsets. Testing capabilities include the following:
> Lympho-hematopoietic stem cells and lymphopoietic progenitor cells
> Lymphocyte proliferation/cytotoxicity assays
> Mixed lymphocyte culture/reaction (MLC/MLR)
> Cytokine Release Syndrome (CRS) and Cytokine Release Assays (CRA)
> Regulatory T-cell (Tregs) response
> Cytotoxic T-cell (CTL) response
> Antibody-dependent cell-mediated cytotoxicity (ADCC)
> Antibody-drug conjugates (ADC)
> Immunophenotyping
> Macrophage (M1/M2) response
> Phagocytosis, oxidative burst (neutrophils), and migration
> NK activity
> Dendritic cell maturation and co-stimulation
> Cell injury and cell death
> Extracellular markers of activation
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