Important: Respiratory Vaccine Availability Update

Dear Provider,


The Beyfortus 50mg (NDC: 49281-0575-15) product's maximum order size in the MIIS has been increased from 40 doses to 100 doses for non-birthing hospital provider sites. Additionally, the Beyfortus 100mg (NDC:49281-0574-15) product’s maximum order size in the MIIS has been increased from 100 doses to 150 doses for all provider sites.


Sites should be ordering sufficient Beyfortus quantities to immunize all eligible infants seen at their practice. Ordering best practice remains ordering smaller quantities more frequently, such that sites should only be ordering between a 2–4 week supply of the Beyfortus in any given order. Please refer to the updated table below for the current ordering constraints for RSV products.

If your site requires more than the maximum order amount of either Beyfortus product over a 2–4 week timeframe, please contact the Vaccine Management Team at 617-983-6828 and ask if a one-time increase is possible (dependent on remaining allocation available). Due to ongoing allocation timing constraints and prioritization of some Beyfortus 50mg doses for birthing hospitals, nirsevimab orders may experience longer turnaround times for approval and shipment when compared to other Respiratory Vaccine orders.

Novavax Not Currently Orderable



The Novavax COVID-19 vaccine (NDC: 80631-0107-10) is not currently orderable in the MIIS system. Novavax lots expiring on 11/30/2024 were not granted a shelf-life extension. Since it is currently less than 18 days until expiry of CDC’s current inventory, no vaccine shipments of Novavax COVID-19 vaccine will be made until additional inventory with longer dated product is available. Doses currently in provider inventories with an expiration date of 11/30/2024 should continue to be administered until their expiration date.


Once CDC receives Novavax COVID-19 vaccine lots with extended expiration dates, ordering of the Novavax product will re-open in the MIIS system. It is expected that additional doses will be received in the coming weeks. In meantime, refer to the updated table below regarding which COVID-19 products are currently available to order in the MIIS.

Vaccine Management Unit
P: 617-983-6828 | F: 617-983-6924