Topics, Trends & Updates

January 2026

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Top Guidelines in 2025

The Clinical Guidelines Program publishes its guidelines on the program website and on the National Library of Medicine bookshelf, which indexes the guidelines in PubMed. Below are the top guidelines in 2025 on each site based on page view.

  1. PEP to Prevent HIV Infection
  2. Management of IRIS
  3. PrEP to Prevent HIV and Promote Sexual Health
  4. Perioperative Care in Adults With HIV
  5. Screening for Anal Dysplasia and Cancer in Adults With HIV
  1. PEP to Prevent HIV Infection
  2. Doxycycline Post-Exposure Prophylaxis to Prevent Bacterial Sexually Transmitted Infections
  3. Treatment of Alcohol Use Disorder
  4. Mycoplasma genitalium Management in Adults
  5. Substance Use Screening, Risk Assessment, and Use Disorder Diagnosis in Adults

Hot Topics

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Don't Miss

Updated:

PEP to Prevent HIV Infection




Updated:

Primary Care for Adults With HIV


Updated:

Clinical Guidance: Stimulant Use



Viremic—Cases in HIV Podcast

Join Hosts Eileen Scully and Christopher Hoffmann as they present cases, explore quandaries in adult HIV care, and discuss key evidence and guidelines that inform clinical decision-making.



New Episodes

Case 12. Injectable ART Failure: Minor Risk of a Major Event: After 3 years on injectable CAB/RPV, a patient develops viremia, with a viral load of ~1,300 copies/mL. Failure of injectable CAB/RPV occurs in 1% to 2%, despite adherence. What factors have been associated with CAB/RPV failure? Can regimen failure be predicted or prevented? Listen as Chris and Eileen discuss the data, their advice to patients considering a switch to injectable CAB/RPV, and their response when failure occurs. Listen Now

Case 13. Got PrEP? HIV Adjacent Care: Like many in HIV, Chris is also a PrEP provider. In this episode, he presents a case to Dr. Rona Vail to work through the best approach to PrEP for a young, gay Black man. They work through the issues of oral vs. injectable PrEP, dosing schedules for oral PrEP, the studies that support each approach, and this patient’s eligibility for each to determine the best recommendations. They end by discussing barriers to PrEP and the importance of choices now that there are so many PrEP options. Listen Now

We’re open to suggestions! To submit a clinical topic for a Viremic case discussion, email us at viremicpodcast@jh.edu.

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Note that we cannot answer questions about the care or treatment of specific patients and cannot provide clinical advice.