New clues show why gold standard treatment for bipolar disorder doesn’t work for majority of patients
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Lithium is considered the gold standard for treating bipolar disorder, but nearly 70 percent of people with bipolar disorder don’t respond to it, leaving them at risk for debilitating, potentially life-threatening mood swings. Researchers led by Salk Professor and President Rusty Gage have found that the culprit may lie in gene activity—or lack of it. Decreased activation of gene called LEF1 is more common in neurons of people with bipolar disorder who do not respond to lithium, pointing way to potential new treatments.
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Click below for select media coverage:
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Scientists search for ways to lock more carbon in the soil
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San Diego Foundation grants $750K to encourage STEM education
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Salk Institute scientists accelerate COVID-19 research
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Remembering San Diegans who passed in 2020
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How a new AI model mimics the brain’s prefrontal cortex
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Congratulations to the recipients of the 2021 Salk Innovation Grant Awards!
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This opportunity, supported since 2006 by Irwin and Joan Jacobs, supports out-of-the-box ideas that hold significant promise but need critical seed funding to grow into large future support. This year, after a competitive peer-review process, three projects from the labs of Shrek Chalasani, Tony Hunter and Geoffrey Wahl have been selected as the recipients of the 2021 Salk Innovation Awards.
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Season 3 of Where Cures Begin podcast
launches in February!
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The third season of Salk’s award-winning podcast, Where Cures Begin, starts on Wednesday, February 3. Listeners will learn from Salk faculty Ron Evans on how hormone receptors are critical for health; Tom Albright on the neuroscience of vision and architecture; Julie Law on how genes are controlled and why it matters; Satchin Panda on how living in sync with your biological clock can improve your health; and others. For more information, or to tune in, visit: www.salk.edu/podcasts.
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NOMIS Center receives $9.5 million to shape the future of research into health and immunity
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Salk Institute welcomes human resources executive Dennis Driver as new trustee
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The Salk Institute Board of Trustees welcomes its newest member, Dennis Driver, who brings a wealth of experience in business and human resources. Driver is senior vice president and chief human resource officer for Theravance Biopharma, Inc., where he’s known for his innovative approach, sense of urgency and entrepreneurial spirit, as well as being an avid proponent of diversity and inclusion.
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Salk postdoctoral fellow awarded over $1 million by National Institutes of Health
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Congratulations to radiation oncologist Heather McGee, a senior postdoctoral fellow in the lab of Susan Kaech, who has been awarded an NIH “Pathway to Independence” grant from the National Cancer Institute for a 5-year project studying how radiation activates cancer-fighting immune cells in different tumor micro-environments. McGee will conduct the research jointly at Salk and UC San Diego.
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Salk postdoctoral fellow garners prestigious neuroscience award
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Congratulations to Nuttida Rungratsameetaweemana, a postdoctoral fellow in the lab of Terrence Sejnowski, for garnering Cell Press' Anuradha Rao Memorial Award. Rungratsameetaweemana uses computational methods to investigate various dynamics of different types of epileptic seizures, with the goal of identifying unique signatures that could be used to guide personalized patient- and type-specific seizure treatment.
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Report describes Salk’s Harnessing Plants Initiative as cutting-edge approach for carbon dioxide removal
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Salk’s Harnessing Plants Initiative, which recently received a major grant from the Bezos Earth Fund, has been included in a new report from the Energy Futures Initiative, titled “From the Ground Up: Cutting-Edge Approaches for Land-Based Carbon Dioxide Removal.”
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31st Annual March of Dimes High School Science Week - February 22-26
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This year’s March of Dimes High School Science Day will take place virtually, and has been extended from one day to an entire week. The annual outreach event was designed to encourage high school students to consider an exciting career in science and research. This year, students will have the opportunity to visit with Salk scientists about their work, take lab tours and participate in current experiments.
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Teachers and students can register for High School Science Week through February 17th.
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For more information on this program, please contact the Education Outreach Department at education@salk.edu.
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Enjoy Salk science on your devices
Looking for a unique background image for your computer, Zoom meeting, iPad or phone?
This month’s image comes from a recent press release from the lab of Rusty Gage. This image shows iPSC-derived dentate gyrus (DG)-like neurons.
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