Join us for the FA Research Flash Talk Series

In honor of FA Awareness month in May, FARA is proud to present: The third annual FA Research Flash Talks series - featuring Young Investigators from FARA funded laboratories around the world. This four-part series will cover key aspects of FARA funded research from gene silencing and disease mechanisms to therapeutic avenues and clinical insights. Each session will include Flash Talks from five Young Investigators (ie, postdocs and graduate students) and will be moderated by an FA Community member. Each Flash Talk will be limited to a maximum of five minutes and a single PowerPoint slide and will be suitable for a lay audience. We will also allott time for a brief Q&A following the talks. Click the button below to register for one, two, three, or all four of the sessions. You will have the option to select which sessions you wish to attend.

Register for the Sessions

Session #1 May 5, 2022 - 12pm ET Moderated by: Jessica Hawley

Structural and Functional Complementation of Human Supercomplex for [Fe-S] Cluster Assembly by the Dictyostelium discoideum Frataxin Justo Olmos, iB3-FCEN-Universidad de Buenos aires Identification of molecular pathways in the pathophysiology of frataxin deficient proprioceptive neurons Deepika Mokkachamy-Chellapandi, Institut NeuroMyoGène Investigating the role of bioactive sphingolipids in Friedreich’s ataxia Saqlain Suleman, Brunel University London Mitochondrial integrated stress response in Friedreich's Ataxia cardiomyopathy Nicole Sayles, Weill Cornell Medicine CRISPR/Cas9-mediated Gene Editing of Hematopoietic Stem and Progenitor Cells  Anusha Sivakumar, University of California, San Diego

Session #2 May 12, 2022 - 12pm ET Moderated by: Cecilia Estrella

Using lab-grown heart cells as a model to study Friedreich's ataxia Soteroulla Ellina, Imperial College London Improving the Quaternary Addition Strategy: Nanobody-based Affinity Clips for FRDA María Florencia Pignataro, iB3-FCEN-Universidad de Buenos Aires Development of an AAV-based gene therapy for the ocular phenotype of Friedreich’s Ataxia Siddhant Gupte, University of Florida Hepcidin-Ferroportin axis in Friedreich´s ataxia Elisabetta Indelicato, Center for Rare Neurological Disorders Innsbruck MyHeart CHOP: An App to Measure and Monitor Exercise Nicolette Cilenti, Children's Hospital of Philadelphia

Session #3 May 19, 2021 - 12pm ET Moderated by: Caroline Spencer

Finding Structure-Function Relationship in the Iron-Sulfur Cluster Assembly Machinery Karl Ellioth Sewell, iB3-FCEN-Universidad de Buenos Aires Partial frataxin bypass on Fe-S clusters biogenesis in murine cellular model Valentine Mosbach, Institut NeuroMyoGène Frataxin controls ketone body metabolism through regulation of OXCT1 Yi Na Dong, Children's Hospital of Philadelphia Now recruiting: The FA Sweet-Heart Study: Glycemia and Echo Findings in Friedreich’s Ataxia  Camilla Whitesel, Children's Hospital of Philadelphia Development & Validation of the Patient-Reported and Caregiver-Reported FA-Health Indices Anika Varma, University of Rochester

Session #4 May 26, 2021 - 12pm ET Moderated by: Mary Nadon-Scott

Somatic GAA expansions as a potential therapeutic target for Friedreich ataxia Maheswaran Kesavan, Massachusetts General Hospital Manipulation of the Frataxin Expression and Function by CRISPR/Cas9 Genome Editing in Dictyostelium discoideum Hernán Gentili, iB3-FCEN-Universidad de Buenos Aires Modeling Friedreich’s ataxia with iPSC-derived brain cells and correction of the defects by gene editing  Priyanka Mishra, University of California, San Diego Exploring the role of frataxin in the mitochondrial phenotype of Friedreich’s ataxia patients’ cells Davide Doni, University of Padova Nicotinamide Riboside improves mitochondrial function in mouse model of Freidreich's Ataxia Caroline Perry, University of Pennsylvania

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