Soothing infants with food may inadvertently teach children to associate food with emotions
New research findings by Jansen and colleagues provides evidence that the use of food to comfort distressed infants may contribute to unhealthy eating behaviors and body composition throughout middle and late childhood. In this large, population-based birth cohort study, parents of 3960 children reported on the use of food to soothe their 6 mo. old infants, and on child eating behavior at age 4 and 10 y. Emotional feeding was assessed by asking mothers if they had comforted their child by providing food or drink in the last 2 wk. Three answering options were provided: never, sometimes, and often. Body composition, which included measurements of body fat mass, bone mass, and lean mass, was measured at ages 6 and 10 y. Eating behaviors of children were assessed with an eating behavior questionnaire, which included two dimensions: emotional overeating and food responsiveness.

Reference : Jansen PW, Derks IPM, Batenburg A, Jaddoe VWV, Franco OH, Verhulst FC, Tiemeier H. Using Food to Soothe in Infancy is Prospectively Associated with Childhood BMI in a Population-Based Cohort . J Nutr . 2019;149(5):788-94. Commentary : Ferraro AA. Anxious Mothers Need Support to Avoid Emotional Feeding of Infants . J Nutr . 2019;149(5):703-4.
For More Information: To contact the corresponding author, Dr. Jansen, send an e-mail to p.w.jansen@erasmusmc.nl . To contact the corresponding author for the commentary, Dr. Ferraro, e-mail feraro@usp.br

Reducing inflammation improves vitamin B-6 status in rheumatoid arthritis patients
Using a new functional biomarker of vitamin B-6, Sande and colleagues investigated vitamin B-6 status in patients with rheumatoid arthritis before and after established treatment with TNFα inhibitors. The study results reveal that improved vitamin B-6 status may be related to reduction of inflammation by TNFα inhibitors. A total of 106 patients participated in this longitudinal study. Eligible patients, aged between 18 and 75 y, were evaluated at baseline and after 3 mo. treatment with TNFα inhibitors. A total of 28 standard joints were assessed and used to calculate a disease activity score. Ultrasonography scores were calculated by adding the score from 32 joints, each rated between 0 and 3 according to severity of inflammation. Responses to treatment with TNFα inhibitors were classified as good responders, moderate responders, or non-responders. After 3 mo. treatment with TNFα inhibitors, clinical parameters improved for the majority of participants, and better clinical response to treatment was associated with a proportional improvement in vitamin B-6 status. These findings highlight the relevance of monitoring vitamin B-6 status during treatment with TNFα inhibitors.

Reference: Sande JS, Ulvik A, Midttun Ø, Ueland PM, Hammer HB, Valen M, Apalset EM, Gjesdal CG. Vitamin B-6 Status Correlates with Disease Activity in Rheumatoid Arthritis Patients During Treatment with TNFα inhibitors . J Nutr . 2019;149(5):770-75.
For More Information: To contact the corresponding author, Dr. Ulvik, please send an e-mail to Arve.Ulvik@uib.no

Frequent consumption of sugar-sweetened soda increases diabetes risk in Mexican women
Based on a cohort of Mexican women, López-Ridaura and colleagues estimated the association between sugar-sweetened soda consumption and diabetes risk. The study also determined if the association between sugar-sweetened soda and diabetes differs as a result of early life factors and potential genetic susceptibility. Data from the Mexican Teachers’ Cohort, utilized for this study, capture a population of adult women already at high susceptibility for diabetes due to genetic or early life exposures to an obesogenic environment. A food frequency questionnaire assessed sugar-sweetened soda consumption among 72,667 women aged >25 y. Researchers hypothesized that greater consumption of sugar-sweetened soda would be associated with a greater incidence of type 2 diabetes, and that the association between sugar-sweetened soda consumption and diabetes would differ by markers of early lifestyle factors and potential genetic susceptibility.

Reference: Stern D, Mazariegos M, Ortiz-Panozo E, Campos H, Malik VS, Lajous M, López-Ridaura R . Sugar-Sweetened Soda Consumption Increases Diabetes Risk Among Mexican Women . J Nutr . 2019;149(5):795-803. Commentary: Balcazar H and Lizaur ABP. Sugar-Sweetened Soda Consumption in Mexico: The Translation of Accumulating Evidence for an Increasing Diabetes Risk in Mexican Women . J Nutr . 2019;149(5):705-7.
For More Information: To contact the corresponding author, Dr. López-Ridaura, send an e-mail to rlridaura@insp.mx . To contact the corresponding author for the commentary, Dr. Balcazar, e-mail hectorbalcazar@cdrewu.edu .

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